| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.356582 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.143976 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.143097 |
| PLEC | plectin | 0.095363 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0861922 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0833748 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0736389 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0605904 |
| KYNU | kynureninase | 0.0602473 |
| ASPH | aspartate beta-hydroxylase | 0.0572168 |
| COL5A1 | collagen, type V, alpha 1 | 0.0571315 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0505243 |
| FTL | ferritin, light polypeptide | 0.0449931 |
| AHNAK | AHNAK nucleoprotein | 0.0440845 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0422868 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0394654 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0384345 |
| GRB10 | growth factor receptor-bound protein 10 | 0.037983 |
| PRSS23 | protease, serine, 23 | 0.0367768 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0365661 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0339917 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0333863 |
| FSTL1 | follistatin-like 1 | 0.0328175 |
| ADM | adrenomedullin | 0.0325152 |
| APP | amyloid beta (A4) precursor protein | 0.0322896 |
| RPS2 | ribosomal protein S2 | 0.0319665 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0314017 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0313801 |
| DGKI | diacylglycerol kinase, iota | 0.0298819 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0297507 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0297128 |
| SDC4 | syndecan 4 | 0.029209 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.02907 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0290527 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0288466 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0286642 |
| H1-4 | H1.4 linker histone, cluster member | 0.0283591 |
| ACTN1 | actinin, alpha 1 | 0.0282286 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0279041 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0278309 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0277009 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0271059 |
| SQSTM1 | sequestosome 1 | 0.0270561 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.026558 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.026407 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0262418 |
| RPL3 | ribosomal protein L3 | 0.0253836 |
| HELZ | helicase with zinc finger | 0.0252962 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0250502 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0242643 |
| TFG | TRK-fused gene | 0.023762 |
| RPLP0 | ribosomal protein, large, P0 | 0.0235593 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0228748 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0226467 |
| HYOU1 | hypoxia up-regulated 1 | 0.0221579 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0221136 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0220745 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0220396 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0220087 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0219114 |
| RPS3 | ribosomal protein S3 | 0.0217379 |
| WDR1 | WD repeat domain 1 | 0.0217255 |
| CORO1C | coronin, actin binding protein, 1C | 0.0217109 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0217029 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0216698 |
| RIGI | RNA sensor RIG-I | 0.0213074 |
| GRAMD1B | GRAM domain containing 1B | 0.0211106 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0209263 |
| MT1X | metallothionein 1X | 0.020773 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0207316 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.020714 |
| TFRC | transferrin receptor | 0.0205007 |
| CUL4B | cullin 4B | 0.0204277 |
| FGF13 | fibroblast growth factor 13 | 0.0201502 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0200884 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0198091 |
| INTS6 | integrator complex subunit 6 | 0.0198016 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.019672 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0194403 |
| HDAC4 | histone deacetylase 4 | 0.0193792 |
| SETBP1 | SET binding protein 1 | 0.0193047 |
| H1-5 | H1.5 linker histone, cluster member | 0.0190523 |
| SKI | SKI proto-oncogene | 0.0188765 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0188118 |
| AEBP2 | AE binding protein 2 | 0.0187212 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0185286 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0184232 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0183655 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0182288 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0181995 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.018187 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0180719 |
| NPTN | neuroplastin | 0.0180478 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.017945 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0179261 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0178407 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.017736 |
| VCL | vinculin | 0.0175627 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0175208 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0174143 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.161319 |
| NDRG1 | N-myc downstream regulated 1 | -0.129065 |
| VIM | vimentin | -0.126805 |
| SBF2 | SET binding factor 2 | -0.101931 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0951034 |
| TMSB10 | thymosin beta 10 | -0.0925108 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.084709 |
| TPM4 | tropomyosin 4 | -0.0822096 |
| RTN4 | reticulon 4 | -0.0784978 |
| TNS3 | tensin 3 | -0.0751237 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0734665 |
| MAP1B | microtubule-associated protein 1B | -0.0724029 |
| EGFR | epidermal growth factor receptor | -0.067491 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0607285 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0570897 |
| CD44 | CD44 molecule (Indian blood group) | -0.0551828 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0543138 |
| POTEF | POTE ankyrin domain family, member F | -0.053793 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0508391 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0503183 |
| GOLGB1 | golgin B1 | -0.049606 |
| GLIS3 | GLIS family zinc finger 3 | -0.0495474 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0482814 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0471427 |
| CALD1 | caldesmon 1 | -0.0467392 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0458949 |
| RPS6 | ribosomal protein S6 | -0.0456069 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0454845 |
| TNNC1 | troponin C type 1 (slow) | -0.0453064 |
| CADM1 | cell adhesion molecule 1 | -0.0445475 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.043748 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0432006 |
| RNF216 | ring finger protein 216 | -0.04317 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0426158 |
| ENO1 | enolase 1, (alpha) | -0.0424467 |
| HLA-B | major histocompatibility complex, class I, B | -0.0419683 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0415359 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0402017 |
| MT2A | metallothionein 2A | -0.040015 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.039369 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0389118 |
| NF1 | neurofibromin 1 | -0.0388864 |
| COG5 | component of oligomeric golgi complex 5 | -0.0378381 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0376018 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0370282 |
| CD99 | CD99 molecule | -0.0364649 |
| ATXN1 | ataxin 1 | -0.0361892 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0357091 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0354903 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0347958 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0343867 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0340768 |
| PHF21A | PHD finger protein 21A | -0.0340696 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0334454 |
| USP47 | ubiquitin specific peptidase 47 | -0.0334155 |
| ATF4 | activating transcription factor 4 | -0.0330386 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0327749 |
| RPL35A | ribosomal protein L35a | -0.0327728 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.031975 |
| SMAD3 | SMAD family member 3 | -0.0319719 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0319147 |
| HMGA1 | high mobility group AT-hook 1 | -0.0318825 |
| QSER1 | glutamine and serine rich 1 | -0.0316002 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.031426 |
| ANXA2 | annexin A2 | -0.0312763 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0312629 |
| SEC24D | SEC24 family member D | -0.0309961 |
| CBX3 | chromobox homolog 3 | -0.0308764 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0307534 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0306934 |
| CDK6 | cyclin-dependent kinase 6 | -0.0304061 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0303938 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0302328 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0300859 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0300044 |
| FN1 | fibronectin 1 | -0.0296017 |
| NAV3 | neuron navigator 3 | -0.0293416 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0292284 |
| YEATS2 | YEATS domain containing 2 | -0.0290304 |
| UBXN4 | UBX domain protein 4 | -0.0286764 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0285382 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0282049 |
| ZNF652 | zinc finger protein 652 | -0.0281184 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0281022 |
| AK1 | adenylate kinase 1 | -0.0278093 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0276943 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0275341 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0274038 |
| COL5A2 | collagen, type V, alpha 2 | -0.0273248 |
| GPC6 | glypican 6 | -0.0273201 |
| IGF2 | insulin-like growth factor 2 | -0.0271204 |
| RPS8 | ribosomal protein S8 | -0.0269927 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0268163 |
| OSMR | oncostatin M receptor | -0.0267758 |
| INHBA | inhibin, beta A | -0.026723 |
| LRRC49 | leucine rich repeat containing 49 | -0.0267038 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0267034 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0266417 |
| FAF2 | Fas associated factor family member 2 | -0.026517 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0265074 |
