| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.187438 |
| AHNAK | AHNAK nucleoprotein | 0.149723 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.134794 |
| DSPP | dentin sialophosphoprotein | 0.0802274 |
| PLEC | plectin | 0.0723723 |
| EZR | ezrin | 0.0657088 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.060266 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0585707 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0535364 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0534493 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0532988 |
| RPS2 | ribosomal protein S2 | 0.047897 |
| RPL3 | ribosomal protein L3 | 0.0465678 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0461995 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0455132 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.044969 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0445675 |
| SQSTM1 | sequestosome 1 | 0.0439259 |
| HSPA8 | heat shock 70kDa protein 8 | 0.043818 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0426997 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0418055 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0410477 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0404796 |
| GOLGA4 | golgin A4 | 0.0403027 |
| FTL | ferritin, light polypeptide | 0.0401346 |
| H1-4 | H1.4 linker histone, cluster member | 0.0378716 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0362801 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0343813 |
| OGA | O-GlcNAcase | 0.0339761 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0339654 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0322151 |
| YME1L1 | YME1-like 1 ATPase | 0.0320759 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0315938 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0310282 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0309706 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0308772 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0307278 |
| CANX | calnexin | 0.0304741 |
| IER2 | immediate early response 2 | 0.0292814 |
| CALR | calreticulin | 0.0283625 |
| PPL | periplakin | 0.0278662 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0277981 |
| SEPTIN9 | septin 9 | 0.027749 |
| KLC1 | kinesin light chain 1 | 0.0276833 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0276393 |
| RPL4 | ribosomal protein L4 | 0.0272995 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0272152 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0264734 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0263691 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0258736 |
| WWC1 | WW and C2 domain containing 1 | 0.0258342 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0258199 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0257694 |
| USP47 | ubiquitin specific peptidase 47 | 0.0257612 |
| MCL1 | myeloid cell leukemia 1 | 0.0255653 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0252305 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0249771 |
| KRT18 | keratin 18, type I | 0.0249524 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0249394 |
| HMGB2 | high mobility group box 2 | 0.0249254 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0245343 |
| SFTPA2 | surfactant protein A2 | 0.0245225 |
| GLG1 | golgi glycoprotein 1 | 0.0244672 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0243882 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0243619 |
| TXNRD1 | thioredoxin reductase 1 | 0.024162 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0241144 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0240601 |
| JUN | jun proto-oncogene | 0.023844 |
| TPM3 | tropomyosin 3 | 0.0237541 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0236057 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0235015 |
| GOLGB1 | golgin B1 | 0.0234135 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.023377 |
| AFDN | afadin, adherens junction formation factor | 0.0231532 |
| UTRN | utrophin | 0.0230041 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0226613 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.022553 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0225098 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0224407 |
| GOLGA3 | golgin A3 | 0.0223899 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0223215 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0222521 |
| ZNF638 | zinc finger protein 638 | 0.0222509 |
| RPS3 | ribosomal protein S3 | 0.0222461 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0222306 |
| CD2AP | CD2-associated protein | 0.0221795 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0221213 |
| ATXN7 | ataxin 7 | 0.0220023 |
| RBM5 | RNA binding motif protein 5 | 0.0219277 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0215792 |
| WWC2 | WW and C2 domain containing 2 | 0.0215618 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0213021 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0212629 |
| TENM3 | teneurin transmembrane protein 3 | 0.021216 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0211945 |
| MACROD2 | MACRO domain containing 2 | 0.0211809 |
| RRBP1 | ribosome binding protein 1 | 0.0211272 |
| LMO7 | LIM domain 7 | 0.0209362 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0208499 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.346783 |
| NDRG1 | N-myc downstream regulated 1 | -0.211867 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.141529 |
| TMSB10 | thymosin beta 10 | -0.13673 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.128794 |
| TUBA1B | tubulin, alpha 1b | -0.0957088 |
| POTEF | POTE ankyrin domain family, member F | -0.0839736 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.078438 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0700329 |
| HMGA1 | high mobility group AT-hook 1 | -0.0654166 |
| RPS24 | ribosomal protein S24 | -0.0583087 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0554412 |
| RAD51B | RAD51 paralog B | -0.0547758 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0515505 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0489166 |
| HMGA2 | high mobility group AT-hook 2 | -0.0482816 |
| RPS6 | ribosomal protein S6 | -0.0480842 |
| S100A9 | S100 calcium binding protein A9 | -0.0480236 |
| DIAPH3 | diaphanous-related formin 3 | -0.0439639 |
| PKM | pyruvate kinase, muscle | -0.0430914 |
| RPL35A | ribosomal protein L35a | -0.0425271 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0416944 |
| PERP | PERP, TP53 apoptosis effector | -0.0393055 |
| HMGB1 | high mobility group box 1 | -0.0392594 |
| PFN1 | profilin 1 | -0.0380509 |
| LDHB | lactate dehydrogenase B | -0.0378772 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0377618 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0371832 |
| DIAPH2 | diaphanous-related formin 2 | -0.0365827 |
| DEK | DEK proto-oncogene | -0.0358013 |
| WWOX | WW domain containing oxidoreductase | -0.0354239 |
| RPS21 | ribosomal protein S21 | -0.0352276 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0350504 |
| CBX3 | chromobox homolog 3 | -0.0348232 |
| MKI67 | marker of proliferation Ki-67 | -0.0343228 |
| NOP58 | NOP58 ribonucleoprotein | -0.0333678 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0332171 |
| TUBB | tubulin, beta class I | -0.032375 |
| HELLS | helicase, lymphoid-specific | -0.0322465 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0320025 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.03174 |
| RPLP0 | ribosomal protein, large, P0 | -0.0315327 |
| LDHA | lactate dehydrogenase A | -0.0313986 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0311263 |
| ENO1 | enolase 1, (alpha) | -0.0308921 |
| RPS23 | ribosomal protein S23 | -0.030567 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0303697 |
| S100A6 | S100 calcium binding protein A6 | -0.0299119 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0297723 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0297271 |
| EGR1 | early growth response 1 | -0.0295621 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.029217 |
| YBX1 | Y box binding protein 1 | -0.0290085 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0285843 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.02849 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0283504 |
| BSG | basigin (Ok blood group) | -0.0281765 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0277968 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0274875 |
| MORC4 | MORC family CW-type zinc finger 4 | -0.0274283 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.0271565 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0270804 |
| RPL32 | ribosomal protein L32 | -0.0262388 |
| MT2A | metallothionein 2A | -0.0261572 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0261167 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0257682 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0256466 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0255833 |
| MEF2A | myocyte enhancer factor 2A | -0.0251772 |
| H2AZ1 | H2A.Z variant histone 1 | -0.0251656 |
| ACTG1 | actin gamma 1 | -0.0246633 |
| CLDN7 | claudin 7 | -0.0245157 |
| UBC | ubiquitin C | -0.0240991 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0235625 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0235464 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0235271 |
| TMEM123 | transmembrane protein 123 | -0.0235055 |
| CCNI | cyclin I | -0.0234939 |
| PDE8A | phosphodiesterase 8A | -0.0233626 |
| PRDX2 | peroxiredoxin 2 | -0.0231844 |
| SERINC5 | serine incorporator 5 | -0.023093 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0229969 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.0229452 |
| CCND1 | cyclin D1 | -0.0228872 |
| RRM2 | ribonucleotide reductase M2 | -0.0228446 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0227137 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0227043 |
| NOP56 | NOP56 ribonucleoprotein | -0.0226663 |
| ZNF207 | zinc finger protein 207 | -0.0226483 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0226466 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0226252 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0224248 |
| ZFHX3 | zinc finger homeobox 3 | -0.0224054 |
| EFHD2 | EF-hand domain family, member D2 | -0.0221458 |
| FBL | fibrillarin | -0.0221316 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0219557 |
| TUBA1C | tubulin, alpha 1c | -0.0219176 |
| RPL11 | ribosomal protein L11 | -0.0218427 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0218349 |
| RPL8 | ribosomal protein L8 | -0.0216715 |
