| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.141266 |
| MT2A | metallothionein 2A | 0.137887 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0918768 |
| TMSB10 | thymosin beta 10 | 0.074781 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0600361 |
| RPL35A | ribosomal protein L35a | 0.0496899 |
| PLEC | plectin | 0.0479319 |
| RPS19 | ribosomal protein S19 | 0.0465366 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0438085 |
| FLNA | filamin A, alpha | 0.0429695 |
| TJP1 | tight junction protein 1 | 0.0424246 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.041253 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0410116 |
| LAMB3 | laminin, beta 3 | 0.0389851 |
| RPL23 | ribosomal protein L23 | 0.0374103 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0357286 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0342836 |
| RPS12 | ribosomal protein S12 | 0.0326977 |
| RPL12 | ribosomal protein L12 | 0.0324022 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0316385 |
| INTS6 | integrator complex subunit 6 | 0.0313476 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0308406 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0307723 |
| CENPF | centromere protein F, 350/400kDa | 0.0305459 |
| SMAD3 | SMAD family member 3 | 0.0294433 |
| ACTN4 | actinin, alpha 4 | 0.0294428 |
| RPS2 | ribosomal protein S2 | 0.0290901 |
| B2M | beta-2-microglobulin | 0.0277674 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.026722 |
| RPL9 | ribosomal protein L9 | 0.0262912 |
| H1-4 | H1.4 linker histone, cluster member | 0.0261993 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.0261921 |
| MT1X | metallothionein 1X | 0.0257282 |
| RPS3 | ribosomal protein S3 | 0.0252516 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0249302 |
| TPI1 | triosephosphate isomerase 1 | 0.0245719 |
| RPL3 | ribosomal protein L3 | 0.0244955 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0243413 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0227844 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0224956 |
| RPS8 | ribosomal protein S8 | 0.0218929 |
| ECT2 | epithelial cell transforming 2 | 0.0216186 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.021199 |
| RPL18 | ribosomal protein L18 | 0.0211687 |
| CBX3 | chromobox homolog 3 | 0.0211082 |
| RPSA | ribosomal protein SA | 0.0208735 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0207658 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0207415 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0205617 |
| RPL26 | ribosomal protein L26 | 0.0205377 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0205319 |
| COG6 | component of oligomeric golgi complex 6 | 0.0202697 |
| AFDN | afadin, adherens junction formation factor | 0.0198142 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0194231 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.019347 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0193282 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0192359 |
| SETX | senataxin | 0.0191052 |
| ASPH | aspartate beta-hydroxylase | 0.0190366 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0187182 |
| RPS9 | ribosomal protein S9 | 0.0186607 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0182802 |
| IER2 | immediate early response 2 | 0.018059 |
| RPL35 | ribosomal protein L35 | 0.0179845 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0178893 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0177093 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0176916 |
| MAMLD1 | mastermind-like domain containing 1 | 0.0176415 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0176242 |
| RPL11 | ribosomal protein L11 | 0.0173721 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0172413 |
| CIP2A | cellular inhibitor of PP2A | 0.0171101 |
| APOL1 | apolipoprotein L, 1 | 0.0170697 |
| RPL34 | ribosomal protein L34 | 0.0169466 |
| RPS27A | ribosomal protein S27a | 0.0167695 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0166522 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0166394 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0166243 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0165963 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0165592 |
| RPL37A | ribosomal protein L37a | 0.0163337 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0163302 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0162837 |
| HMGB2 | high mobility group box 2 | 0.0162246 |
| CPNE1 | copine I | 0.0160014 |
| RPS21 | ribosomal protein S21 | 0.0157111 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0156488 |
| BCL2L1 | BCL2-like 1 | 0.0156196 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0155644 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0153945 |
| HMGB1 | high mobility group box 1 | 0.0153318 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0150515 |
| RPL23A | ribosomal protein L23a | 0.0150328 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | 0.0150126 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.014999 |
| ACTN1 | actinin, alpha 1 | 0.0147918 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0147875 |
| COX6C | cytochrome c oxidase subunit VIc | 0.0145421 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0145242 |
| ATP5MK | ATP synthase membrane subunit k | 0.014519 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.155036 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139995 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135082 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.108432 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.107662 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0979229 |
| AHNAK | AHNAK nucleoprotein | -0.0925232 |
| LDHA | lactate dehydrogenase A | -0.0909841 |
| ANXA2 | annexin A2 | -0.0879817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.08755 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0842208 |
| EGFR | epidermal growth factor receptor | -0.083577 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.08011 |
| FLNB | filamin B, beta | -0.0786336 |
| APP | amyloid beta (A4) precursor protein | -0.0767992 |
| TPM4 | tropomyosin 4 | -0.0734258 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0720689 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0700616 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0670153 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0668215 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0651787 |
| SSH2 | slingshot protein phosphatase 2 | -0.0641232 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0635881 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0616754 |
| ZNF292 | zinc finger protein 292 | -0.0615922 |
| NDRG1 | N-myc downstream regulated 1 | -0.0604393 |
| RAD51B | RAD51 paralog B | -0.0604009 |
| NF1 | neurofibromin 1 | -0.0589238 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.058204 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0564044 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0561052 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0533529 |
| CCND1 | cyclin D1 | -0.0530964 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.052374 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0522829 |
| BBX | bobby sox homolog (Drosophila) | -0.051633 |
| FNIP1 | folliculin interacting protein 1 | -0.0514669 |
| SBF2 | SET binding factor 2 | -0.0512961 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0503168 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0500803 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0487168 |
| MAP4 | microtubule-associated protein 4 | -0.0485415 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0474973 |
| JMJD1C | jumonji domain containing 1C | -0.0474403 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0466901 |
| TXNRD1 | thioredoxin reductase 1 | -0.0463584 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0460956 |
| CANX | calnexin | -0.0456778 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0447362 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0441322 |
| PTK2 | protein tyrosine kinase 2 | -0.0438451 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0438214 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0431899 |
| TAOK1 | TAO kinase 1 | -0.0427167 |
| PKM | pyruvate kinase, muscle | -0.0406644 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0405204 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0399872 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0392057 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0391658 |
| LAMA4 | laminin, alpha 4 | -0.039106 |
| CDCP1 | CUB domain containing protein 1 | -0.0386208 |
| HELZ | helicase with zinc finger | -0.0383655 |
| TPD52 | tumor protein D52 | -0.0380542 |
| RLF | rearranged L-myc fusion | -0.0374158 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0369445 |
| CLINT1 | clathrin interactor 1 | -0.0369199 |
| RUNX1 | runt-related transcription factor 1 | -0.0367724 |
| EREG | epiregulin | -0.0365967 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0364964 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.036238 |
| ACACA | acetyl-CoA carboxylase alpha | -0.03606 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0359398 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0355269 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0348142 |
| SETD2 | SET domain containing 2 | -0.0347556 |
| EMP1 | epithelial membrane protein 1 | -0.034717 |
| PCED1B | PC-esterase domain containing 1B | -0.0346584 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0344149 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0338447 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0338083 |
| PARD3 | par-3 family cell polarity regulator | -0.0336239 |
| ZNF609 | zinc finger protein 609 | -0.0330171 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0329743 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0318683 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0317573 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0315958 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0314894 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0314562 |
| SLMAP | sarcolemma associated protein | -0.0312003 |
| CALR | calreticulin | -0.0310068 |
| UBC | ubiquitin C | -0.0307439 |
| ENO1 | enolase 1, (alpha) | -0.0305213 |
| SVIL | supervillin | -0.0305 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0303518 |
| WDR45B | WD repeat domain 45B | -0.0300881 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0300473 |
| RHOA | ras homolog family member A | -0.0298233 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0296334 |
| MATR3 | matrin 3 | -0.0295145 |
| LOC112694756 | uncharaterized LOC112694756 | -0.029464 |
