| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.214338 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.200377 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.187608 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.134301 |
| MT2A | metallothionein 2A | 0.124536 |
| PLEC | plectin | 0.115193 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.11089 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.110711 |
| COL6A3 | collagen, type VI, alpha 3 | 0.105687 |
| MSN | moesin | 0.103608 |
| COL5A1 | collagen, type V, alpha 1 | 0.0994493 |
| MAP1B | microtubule-associated protein 1B | 0.0899122 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0885427 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0879469 |
| MYO10 | myosin X | 0.0877774 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0849724 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.082113 |
| SEPTIN9 | septin 9 | 0.0797165 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0783474 |
| ASPH | aspartate beta-hydroxylase | 0.07762 |
| DST | dystonin | 0.0770797 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0673878 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0652748 |
| TMSB10 | thymosin beta 10 | 0.0652207 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0647491 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0621655 |
| TPI1 | triosephosphate isomerase 1 | 0.0610029 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0592315 |
| AHNAK | AHNAK nucleoprotein | 0.0578039 |
| TPM3 | tropomyosin 3 | 0.0577149 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0575504 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0544695 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.054469 |
| NAV1 | neuron navigator 1 | 0.0530061 |
| ANGPTL4 | angiopoietin-like 4 | 0.0527748 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0524147 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0522696 |
| MT1X | metallothionein 1X | 0.050744 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.050413 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0499694 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0498168 |
| HSPA8 | heat shock 70kDa protein 8 | 0.047692 |
| ACTN1 | actinin, alpha 1 | 0.0473923 |
| ENO1 | enolase 1, (alpha) | 0.0472691 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0469883 |
| CD44 | CD44 molecule (Indian blood group) | 0.0465631 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0462721 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0455416 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0449162 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0445938 |
| STC1 | stanniocalcin 1 | 0.0442844 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0440487 |
| PRSS23 | protease, serine, 23 | 0.043858 |
| LAMB3 | laminin, beta 3 | 0.0426487 |
| RRM2 | ribonucleotide reductase M2 | 0.0425647 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0418672 |
| CLIC4 | chloride intracellular channel 4 | 0.0412172 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0411585 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0409637 |
| WWOX | WW domain containing oxidoreductase | 0.0403933 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0401741 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0394074 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0389734 |
| TNS1 | tensin 1 | 0.038794 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.038269 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0380225 |
| MCL1 | myeloid cell leukemia 1 | 0.0378651 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0378628 |
| CENPF | centromere protein F, 350/400kDa | 0.0369533 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0364798 |
| G0S2 | G0/G1 switch 2 | 0.0363796 |
| CAPRIN2 | caprin family member 2 | 0.0362128 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0360589 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0355006 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0354309 |
| DSPP | dentin sialophosphoprotein | 0.0348894 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0347623 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0343983 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0342091 |
| SFPQ | splicing factor proline/glutamine-rich | 0.034182 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0341111 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0334664 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0334645 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0331594 |
| RPL3 | ribosomal protein L3 | 0.0329763 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0325868 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0324055 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0322422 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0314973 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.031385 |
| SET | SET nuclear proto-oncogene | 0.0311415 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0310411 |
| EGFR | epidermal growth factor receptor | 0.031038 |
| LMNA | lamin A/C | 0.0309124 |
| FAM13A | family with sequence similarity 13, member A | 0.0307618 |
| JUN | jun proto-oncogene | 0.0304397 |
| RPS6 | ribosomal protein S6 | 0.0302345 |
| B2M | beta-2-microglobulin | 0.0299759 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0297071 |
| FAT1 | FAT atypical cadherin 1 | 0.0296301 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.239279 |
| FN1 | fibronectin 1 | -0.172127 |
| VIM | vimentin | -0.159313 |
| IGF2 | insulin-like growth factor 2 | -0.131967 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.104308 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0870466 |
| CDH13 | cadherin 13 | -0.0827716 |
| CDCP1 | CUB domain containing protein 1 | -0.0636248 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0580364 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0501939 |
| LOX | lysyl oxidase | -0.0498172 |
| SBF2 | SET binding factor 2 | -0.048712 |
| PDE10A | phosphodiesterase 10A | -0.0463194 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0438623 |
| OSMR | oncostatin M receptor | -0.0428123 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0423818 |
| GLIS3 | GLIS family zinc finger 3 | -0.0415215 |
| NDRG1 | N-myc downstream regulated 1 | -0.0406133 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0404125 |
| COL1A1 | collagen, type I, alpha 1 | -0.0382055 |
| CD109 | CD109 molecule | -0.0374394 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0366534 |
| TENM2 | teneurin transmembrane protein 2 | -0.0350901 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.034395 |
| NGLY1 | N-glycanase 1 | -0.0343837 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0341894 |
| ANKRD12 | ankyrin repeat domain 12 | -0.033998 |
| RPS24 | ribosomal protein S24 | -0.033581 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0334826 |
| RPLP1 | ribosomal protein, large, P1 | -0.0329334 |
| HMGA2 | high mobility group AT-hook 2 | -0.0328976 |
| TMEM165 | transmembrane protein 165 | -0.032752 |
| GOLGA4 | golgin A4 | -0.0322704 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0320027 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0307088 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0304416 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0302586 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0290673 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0276802 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.026255 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0261599 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0259533 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0254175 |
| RPL38 | ribosomal protein L38 | -0.0253831 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0252699 |
| ANXA2 | annexin A2 | -0.0248683 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0247597 |
| RPS16 | ribosomal protein S16 | -0.0246202 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0245837 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0238151 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0236952 |
| FMN1 | formin 1 | -0.0233747 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0233235 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0232875 |
| RPL35A | ribosomal protein L35a | -0.0231406 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0229707 |
| TNNC1 | troponin C type 1 (slow) | -0.0229373 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0227037 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0225191 |
| WDR45B | WD repeat domain 45B | -0.0223085 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0222699 |
| SGO2 | shugoshin 2 | -0.0221971 |
| CLMP | CXADR-like membrane protein | -0.0220444 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0215488 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0213719 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0209111 |
| TMEM263 | transmembrane protein 263 | -0.0202679 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.020236 |
| RNF149 | ring finger protein 149 | -0.0201529 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0200073 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0198541 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0198221 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0196724 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0194958 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0193934 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0193064 |
| RPL39 | ribosomal protein L39 | -0.0192822 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0192025 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -0.0187617 |
| ACTG1 | actin gamma 1 | -0.0186978 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0185343 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0183945 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0182905 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0182243 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0181195 |
| PCNX4 | pecanex 4 | -0.0179937 |
| FOXJ3 | forkhead box J3 | -0.0179351 |
| CEP350 | centrosomal protein 350kDa | -0.0179085 |
| POM121 | POM121 transmembrane nucleoporin | -0.0177271 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0174985 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0173481 |
| ENOSF1 | enolase superfamily member 1 | -0.0172934 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0171882 |
| OGA | O-GlcNAcase | -0.0171789 |
| FNIP1 | folliculin interacting protein 1 | -0.017159 |
| TAOK1 | TAO kinase 1 | -0.0169886 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0169781 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.016762 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0167605 |
| SERINC2 | serine incorporator 2 | -0.0166314 |
