| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEC | plectin | 0.104667 |
| SMAD3 | SMAD family member 3 | 0.100116 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0921478 |
| CTBP2 | C-terminal binding protein 2 | 0.087848 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0693672 |
| AHNAK | AHNAK nucleoprotein | 0.0653037 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0628984 |
| EPS8L1 | EPS8-like 1 | 0.0623429 |
| HYOU1 | hypoxia up-regulated 1 | 0.0605096 |
| INTS6 | integrator complex subunit 6 | 0.0594251 |
| FNDC3B | fibronectin type III domain containing 3B | 0.057314 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0529254 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.051349 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0492258 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0481339 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0429943 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0429827 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0405169 |
| PPL | periplakin | 0.0397197 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0383569 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0373421 |
| FAM13A | family with sequence similarity 13, member A | 0.0359513 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0357176 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0353717 |
| SMYD3 | SET and MYND domain containing 3 | 0.0353057 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0350979 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0349629 |
| FAT1 | FAT atypical cadherin 1 | 0.0348268 |
| UTRN | utrophin | 0.0345425 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0334924 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0333276 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0332737 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0327295 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0323263 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0321644 |
| SETX | senataxin | 0.0321083 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0317235 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0315127 |
| SEPTIN9 | septin 9 | 0.0312793 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0311295 |
| KRT8 | keratin 8, type II | 0.0310334 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0304292 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0303482 |
| EGFR | epidermal growth factor receptor | 0.0301869 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0298964 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0296598 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0294284 |
| GOLGA3 | golgin A3 | 0.0293575 |
| KRT18 | keratin 18, type I | 0.0285449 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0281371 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.027831 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0276738 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.027486 |
| YAP1 | Yes-associated protein 1 | 0.0273411 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0271112 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0269492 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0268791 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0268753 |
| NEBL | nebulette | 0.0262083 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0255762 |
| DOCK1 | dedicator of cytokinesis 1 | 0.025546 |
| MLPH | melanophilin | 0.0253912 |
| FLNA | filamin A, alpha | 0.0252619 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0248774 |
| VIM | vimentin | 0.0247776 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0247495 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0245063 |
| OGA | O-GlcNAcase | 0.0241759 |
| WLS | wntless Wnt ligand secretion mediator | 0.0241448 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0240661 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0239759 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0238834 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0237408 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0236354 |
| ATXN1 | ataxin 1 | 0.0236009 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0235675 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0234044 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0232985 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0232002 |
| KIAA0232 | KIAA0232 | 0.0231632 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0230359 |
| PGM3 | phosphoglucomutase 3 | 0.0227737 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0227015 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0224774 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0223975 |
| RPL3 | ribosomal protein L3 | 0.0222958 |
| LMO7 | LIM domain 7 | 0.0222126 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0221932 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0220113 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0217191 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0212525 |
| FLNB | filamin B, beta | 0.0210358 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0208784 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0208403 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.020833 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0207493 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0206931 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.020623 |
| SETD5 | SET domain containing 5 | 0.0205381 |
| DIDO1 | death inducer-obliterator 1 | 0.0205244 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ANXA2 | annexin A2 | -0.147964 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.128322 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.122227 |
| EGR1 | early growth response 1 | -0.119148 |
| TXNRD1 | thioredoxin reductase 1 | -0.113758 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.110154 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0927555 |
| FTL | ferritin, light polypeptide | -0.089928 |
| KRT20 | keratin 20, type I | -0.0877619 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0844501 |
| TRIB1 | tribbles pseudokinase 1 | -0.0834249 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0823648 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0776794 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0771793 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0752012 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0744058 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0727221 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0694409 |
| RPLP1 | ribosomal protein, large, P1 | -0.0645988 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0616362 |
| VCL | vinculin | -0.0613622 |
| DIAPH2 | diaphanous-related formin 2 | -0.0608059 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.058951 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0583197 |
| KLF6 | Kruppel-like factor 6 | -0.0577237 |
| S100A6 | S100 calcium binding protein A6 | -0.0569836 |
| PTMA | prothymosin, alpha | -0.0567057 |
| FRY | furry homolog (Drosophila) | -0.055752 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0554204 |
| TMEM123 | transmembrane protein 123 | -0.0546808 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0541695 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0535082 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0532845 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0531068 |
| RPLP0 | ribosomal protein, large, P0 | -0.0526169 |
| RPS19 | ribosomal protein S19 | -0.0512193 |
| RPS6 | ribosomal protein S6 | -0.0510999 |
| RPL23 | ribosomal protein L23 | -0.0509981 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0505617 |
| MUC13 | mucin 13, cell surface associated | -0.0502751 |
| LDHA | lactate dehydrogenase A | -0.0502613 |
| ACTG1 | actin gamma 1 | -0.0499381 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0475648 |
| ETV6 | ets variant 6 | -0.0466405 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.046633 |
| JUP | junction plakoglobin | -0.0459394 |
| CLDN4 | claudin 4 | -0.0447532 |
| RPS24 | ribosomal protein S24 | -0.0429242 |
| LIMA1 | LIM domain and actin binding 1 | -0.0425237 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0425128 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0421977 |
| CD2AP | CD2-associated protein | -0.0419395 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0416668 |
| EZR | ezrin | -0.0416134 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.041538 |
| LYZ | lysozyme | -0.0408049 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0403448 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0398886 |
| RPS3 | ribosomal protein S3 | -0.0395149 |
| TJP1 | tight junction protein 1 | -0.0392054 |
| RPL12 | ribosomal protein L12 | -0.0387879 |
| RPL34 | ribosomal protein L34 | -0.0385356 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0379126 |
| EPCAM | epithelial cell adhesion molecule | -0.0375858 |
| RPS16 | ribosomal protein S16 | -0.0373483 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0368717 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0360165 |
| RPL18 | ribosomal protein L18 | -0.0348693 |
| WASF2 | WAS protein family, member 2 | -0.034657 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0345928 |
| HMGA1 | high mobility group AT-hook 1 | -0.0344387 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0343467 |
| TMSB10 | thymosin beta 10 | -0.034196 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.033725 |
| TMEM65 | transmembrane protein 65 | -0.033715 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0336898 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0335556 |
| RTN4 | reticulon 4 | -0.0335146 |
| RPS12 | ribosomal protein S12 | -0.0331445 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0328305 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0327039 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0326203 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0324124 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.031932 |
| B2M | beta-2-microglobulin | -0.0316603 |
| POTEF | POTE ankyrin domain family, member F | -0.0316534 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.031649 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0315849 |
| KIF5B | kinesin family member 5B | -0.0309318 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0309169 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0308901 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0308292 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0304337 |
| RACK1 | receptor for activated C kinase 1 | -0.0300631 |
| RNF213 | ring finger protein 213 | -0.0300432 |
| DGKH | diacylglycerol kinase, eta | -0.0300124 |
| FOSL1 | FOS-like antigen 1 | -0.0299704 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.029807 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0297729 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0296772 |
