| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.140511 |
| LMO7 | LIM domain 7 | 0.132386 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.128792 |
| MSN | moesin | 0.0944718 |
| PLEC | plectin | 0.0854061 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0814465 |
| LAMC2 | laminin, gamma 2 | 0.0800138 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0594654 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0569687 |
| MYOF | myoferlin | 0.0531532 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0530016 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0510769 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0504368 |
| ASPH | aspartate beta-hydroxylase | 0.0496076 |
| PRSS23 | protease, serine, 23 | 0.0487635 |
| RIGI | RNA sensor RIG-I | 0.0482845 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0478589 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0460897 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0459458 |
| VCL | vinculin | 0.044227 |
| SMAD3 | SMAD family member 3 | 0.0438471 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.043778 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0420539 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0420518 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0419622 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0409836 |
| GOLGB1 | golgin B1 | 0.0404618 |
| INTS6 | integrator complex subunit 6 | 0.039025 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0389965 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0389686 |
| LUZP1 | leucine zipper protein 1 | 0.0386068 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0385311 |
| DIAPH1 | diaphanous-related formin 1 | 0.0373821 |
| RASAL2 | RAS protein activator like 2 | 0.0371858 |
| ANXA1 | annexin A1 | 0.0362639 |
| DSPP | dentin sialophosphoprotein | 0.0360781 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0360294 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.035497 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0344627 |
| RPS2 | ribosomal protein S2 | 0.0335995 |
| ACTN1 | actinin, alpha 1 | 0.0335586 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0333624 |
| AMOTL1 | angiomotin like 1 | 0.0332766 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0330803 |
| TMSB4X | thymosin beta 4, X-linked | 0.0327542 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0324916 |
| MTSS1 | metastasis suppressor 1 | 0.0317716 |
| SQSTM1 | sequestosome 1 | 0.031689 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0315116 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0314894 |
| TPM3 | tropomyosin 3 | 0.0307021 |
| EZR | ezrin | 0.0302236 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0298868 |
| CALB1 | calbindin 1, 28kDa | 0.0294112 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0282244 |
| SEPTIN9 | septin 9 | 0.027987 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278977 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.027498 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0274669 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0271884 |
| RAI14 | retinoic acid induced 14 | 0.0270588 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0266749 |
| SET | SET nuclear proto-oncogene | 0.026491 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0263669 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0261476 |
| CLIC4 | chloride intracellular channel 4 | 0.0260724 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0260057 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0259766 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0259486 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0258912 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0256608 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0254405 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0252955 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0252862 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0246699 |
| TSPAN3 | tetraspanin 3 | 0.024521 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0244951 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0242936 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0240827 |
| SIK3 | SIK family kinase 3 | 0.0239694 |
| RCOR1 | REST corepressor 1 | 0.0237347 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0236515 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0234855 |
| EGFR | epidermal growth factor receptor | 0.0234039 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0233762 |
| SVIL | supervillin | 0.0232251 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0230368 |
| FAM107B | family with sequence similarity 107, member B | 0.0229685 |
| CTBP2 | C-terminal binding protein 2 | 0.0227154 |
| MCL1 | myeloid cell leukemia 1 | 0.0226115 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0225751 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0225245 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0219372 |
| CPNE1 | copine I | 0.0218523 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0218292 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0217424 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0215839 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0214009 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0212704 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0212497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.150325 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138038 |
| FLNB | filamin B, beta | -0.104533 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0990537 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0849778 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0718941 |
| POTEF | POTE ankyrin domain family, member F | -0.0715749 |
| IGF2 | insulin-like growth factor 2 | -0.0713774 |
| PODXL | podocalyxin-like | -0.0661455 |
| PTMA | prothymosin, alpha | -0.0612065 |
| OSMR | oncostatin M receptor | -0.0533089 |
| LAMA5 | laminin, alpha 5 | -0.0514015 |
| S100A10 | S100 calcium binding protein A10 | -0.0502186 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0487113 |
| MEF2A | myocyte enhancer factor 2A | -0.048615 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0484819 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0467092 |
| GNAS | GNAS complex locus | -0.0466721 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0454077 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0444758 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0426112 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0418025 |
| HLA-B | major histocompatibility complex, class I, B | -0.0411419 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0394823 |
| TMEM165 | transmembrane protein 165 | -0.0383355 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0381898 |
| RPS21 | ribosomal protein S21 | -0.037785 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0368517 |
| NRG1 | neuregulin 1 | -0.0367593 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0364743 |
| S100A2 | S100 calcium binding protein A2 | -0.0363311 |
| C4BPB | complement component 4 binding protein, beta | -0.0359896 |
| RPS24 | ribosomal protein S24 | -0.0350544 |
| RIN2 | Ras and Rab interactor 2 | -0.0346015 |
| LDHA | lactate dehydrogenase A | -0.0344705 |
| NEK7 | NIMA-related kinase 7 | -0.0344552 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.034359 |
| CD99 | CD99 molecule | -0.034171 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0337836 |
| RPL27A | ribosomal protein L27a | -0.0327137 |
| RPS25 | ribosomal protein S25 | -0.0319015 |
| SULF1 | sulfatase 1 | -0.0312204 |
| PLAT | plasminogen activator, tissue | -0.0306268 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0305584 |
| KIAA1217 | KIAA1217 | -0.0304461 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.030371 |
| LMAN1 | lectin, mannose-binding, 1 | -0.030367 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0303511 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0303092 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0299317 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0298532 |
| FOXO1 | forkhead box O1 | -0.0297586 |
| HM13 | histocompatibility (minor) 13 | -0.0296685 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0295622 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0295553 |
| TMSB10 | thymosin beta 10 | -0.0295272 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0294446 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0292422 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.029205 |
| H1-0 | H1.0 linker histone | -0.0291811 |
| RPL35A | ribosomal protein L35a | -0.0290917 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0287353 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0282817 |
| RPLP2 | ribosomal protein, large, P2 | -0.0282681 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0282498 |
| RPS13 | ribosomal protein S13 | -0.028113 |
| BCL2L1 | BCL2-like 1 | -0.0280124 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0279062 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0277839 |
| RNF145 | ring finger protein 145 | -0.0273521 |
| RPL36A | ribosomal protein L36a | -0.027159 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0271139 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0268027 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0264771 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.026007 |
| RBM39 | RNA binding motif protein 39 | -0.025908 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0254908 |
| CAVIN1 | caveolae associated protein 1 | -0.025365 |
| BSG | basigin (Ok blood group) | -0.0251753 |
| WASF2 | WAS protein family, member 2 | -0.0250711 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0249093 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0248935 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0248708 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.024849 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0245619 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0241709 |
| EFHD2 | EF-hand domain family, member D2 | -0.0241688 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0241097 |
| ANLN | anillin, actin binding protein | -0.0240201 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0237831 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0236958 |
| GOLGA4 | golgin A4 | -0.023654 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0234872 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0234387 |
| STC1 | stanniocalcin 1 | -0.0233882 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0233601 |
| FOXP1 | forkhead box P1 | -0.0233422 |
| SLMAP | sarcolemma associated protein | -0.0230408 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.022802 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0226312 |
