| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.181545 |
| EXT1 | exostosin glycosyltransferase 1 | 0.109765 |
| INTS6 | integrator complex subunit 6 | 0.0876598 |
| ERBIN | erbb2 interacting protein | 0.077849 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0755657 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0616278 |
| ASPH | aspartate beta-hydroxylase | 0.0604191 |
| TLE4 | transducin-like enhancer of split 4 | 0.056676 |
| MSN | moesin | 0.0539645 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0507789 |
| DST | dystonin | 0.0498175 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0490937 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0464162 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0457923 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0428539 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0426033 |
| PLEC | plectin | 0.0425173 |
| VCL | vinculin | 0.042047 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0411384 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0406631 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.0404466 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0397599 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0373923 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0372301 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0369036 |
| ACTN1 | actinin, alpha 1 | 0.036543 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0356248 |
| FLNA | filamin A, alpha | 0.0355285 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0343859 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0339323 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0335575 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0320872 |
| AHNAK | AHNAK nucleoprotein | 0.0317144 |
| CALD1 | caldesmon 1 | 0.0306151 |
| NAV2 | neuron navigator 2 | 0.0304364 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0303682 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0302588 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0301911 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0297626 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.029485 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0294367 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0292336 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0288073 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0282849 |
| TPM3 | tropomyosin 3 | 0.027711 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0276277 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0274706 |
| SMYD3 | SET and MYND domain containing 3 | 0.0274316 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0268088 |
| SET | SET nuclear proto-oncogene | 0.0267764 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0267714 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0266962 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0264042 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0258689 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0257544 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0257442 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0252904 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0251835 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0247066 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0245783 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0243352 |
| CTBP2 | C-terminal binding protein 2 | 0.0242675 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0242007 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0240388 |
| CLIC4 | chloride intracellular channel 4 | 0.0240202 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0237068 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0236509 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0235994 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.023205 |
| CAVIN1 | caveolae associated protein 1 | 0.0231761 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0228661 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0228169 |
| AEBP2 | AE binding protein 2 | 0.0227112 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0226079 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0225348 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0221883 |
| RPS2 | ribosomal protein S2 | 0.021692 |
| CPNE1 | copine I | 0.0214087 |
| RBBP6 | retinoblastoma binding protein 6 | 0.02131 |
| SMAD3 | SMAD family member 3 | 0.0210997 |
| H1-4 | H1.4 linker histone, cluster member | 0.0210554 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0209561 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0205209 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0204633 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0204368 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0204111 |
| ATXN1 | ataxin 1 | 0.0203063 |
| ANKRD11 | ankyrin repeat domain 11 | 0.020213 |
| MTAP | methylthioadenosine phosphorylase | 0.0202102 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0200948 |
| E2F3 | E2F transcription factor 3 | 0.0200888 |
| EXOC4 | exocyst complex component 4 | 0.020055 |
| RASAL2 | RAS protein activator like 2 | 0.0200386 |
| DIAPH3 | diaphanous-related formin 3 | 0.0198953 |
| RB1 | retinoblastoma 1 | 0.019879 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0197382 |
| PRELID2 | PRELI domain containing 2 | 0.0195674 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0195005 |
| NABP1 | nucleic acid binding protein 1 | 0.0194145 |
| ADIPOR2 | adiponectin receptor 2 | 0.0193648 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.280675 |
| FN1 | fibronectin 1 | -0.237453 |
| FTL | ferritin, light polypeptide | -0.211926 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.169562 |
| HLA-B | major histocompatibility complex, class I, B | -0.167094 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.160271 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.136385 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.10446 |
| NDRG1 | N-myc downstream regulated 1 | -0.103011 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0930467 |
| DEK | DEK proto-oncogene | -0.091136 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0895069 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0791745 |
| MT1X | metallothionein 1X | -0.0703228 |
| ANXA2 | annexin A2 | -0.0640587 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0637166 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0627048 |
| LDHA | lactate dehydrogenase A | -0.0615709 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0606043 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0599095 |
| GOLGA4 | golgin A4 | -0.0580556 |
| ARF4 | ADP-ribosylation factor 4 | -0.0538564 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0509432 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0483951 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0469209 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0427312 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0415017 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0409156 |
| ANXA1 | annexin A1 | -0.0404972 |
| FOSL1 | FOS-like antigen 1 | -0.0402247 |
| CALR | calreticulin | -0.040175 |
| UBC | ubiquitin C | -0.0400541 |
| PLIN2 | perilipin 2 | -0.0394317 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0387779 |
| CTSD | cathepsin D | -0.038304 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0381689 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0381513 |
| LOX | lysyl oxidase | -0.0370286 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0366581 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0357991 |
| POSTN | periostin, osteoblast specific factor | -0.035582 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0353205 |
| RLF | rearranged L-myc fusion | -0.0347122 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0343322 |
| ZNF292 | zinc finger protein 292 | -0.0336422 |
| OSMR | oncostatin M receptor | -0.0332501 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0327349 |
| WDR45B | WD repeat domain 45B | -0.0324482 |
| HLA-E | major histocompatibility complex, class I, E | -0.032315 |
| ZFR | zinc finger RNA binding protein | -0.0321761 |
| MMP12 | matrix metallopeptidase 12 | -0.0318804 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0308852 |
| PGK1 | phosphoglycerate kinase 1 | -0.0307411 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0306815 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0305521 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0305157 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0300875 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0297455 |
| HLA-A | major histocompatibility complex, class I, A | -0.0295906 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0293268 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0292622 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0288214 |
| B2M | beta-2-microglobulin | -0.0286686 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.028253 |
| PFN1 | profilin 1 | -0.0280537 |
| TXNRD1 | thioredoxin reductase 1 | -0.0280321 |
| SEC24A | SEC24 family member A | -0.0277047 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0276184 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0275523 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.027238 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0271547 |
| TRAM1 | translocation associated membrane protein 1 | -0.0270603 |
| PDE10A | phosphodiesterase 10A | -0.0264658 |
| TUBB | tubulin, beta class I | -0.0263157 |
| NOP58 | NOP58 ribonucleoprotein | -0.0260749 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0259995 |
| DENND4C | DENN/MADD domain containing 4C | -0.0254646 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0253988 |
| RPLP1 | ribosomal protein, large, P1 | -0.0253667 |
| NUP58 | nucleoporin 58 | -0.0253111 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0250407 |
| KIAA1958 | KIAA1958 | -0.0249297 |
| MTDH | metadherin | -0.0248525 |
| SUCO | SUN domain containing ossification factor | -0.0247499 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.024436 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0243697 |
| ATP13A3 | ATPase type 13A3 | -0.0243056 |
| DTNA | dystrobrevin, alpha | -0.0241796 |
| TMSB10 | thymosin beta 10 | -0.0237019 |
| TPD52 | tumor protein D52 | -0.0236287 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0235836 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0233142 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0230115 |
| S100A6 | S100 calcium binding protein A6 | -0.0229431 |
| RIOK3 | RIO kinase 3 | -0.022817 |
| SULF1 | sulfatase 1 | -0.0227707 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0226734 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.022174 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0221165 |
| INSIG2 | insulin induced gene 2 | -0.0219484 |
