| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.0438137 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0406899 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0390116 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0387557 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0363851 |
| PLEC | plectin | 0.029814 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.027568 |
| AEBP2 | AE binding protein 2 | 0.0264948 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0260459 |
| VCL | vinculin | 0.0258282 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0241613 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0224359 |
| CPNE1 | copine I | 0.0205314 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0204443 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0202686 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0189808 |
| FLNA | filamin A, alpha | 0.0185599 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0176502 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0173031 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0173005 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0169342 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0168496 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0164094 |
| HMGA2 | high mobility group AT-hook 2 | 0.0161203 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0160985 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0160107 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0159441 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0159051 |
| NABP1 | nucleic acid binding protein 1 | 0.0158425 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0158342 |
| H1-4 | H1.4 linker histone, cluster member | 0.0150247 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0149914 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0149528 |
| RCC1 | regulator of chromosome condensation 1 | 0.0149101 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0148419 |
| PUM3 | pumilio RNA binding family member 3 | 0.0147357 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0146775 |
| RPL23 | ribosomal protein L23 | 0.0144651 |
| ZNF638 | zinc finger protein 638 | 0.0135174 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0132751 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0131739 |
| CORO1C | coronin, actin binding protein, 1C | 0.0130903 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0125872 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0125317 |
| RASA3 | RAS p21 protein activator 3 | 0.0125038 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.012452 |
| KLHL29 | kelch-like family member 29 | 0.0123616 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.012277 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0121343 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0120898 |
| GCNA | germ cell nuclear acidic peptidase | 0.0120494 |
| SECISBP2 | SECIS binding protein 2 | 0.0117511 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0116839 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0115958 |
| TLE4 | transducin-like enhancer of split 4 | 0.0115797 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0114879 |
| CD163L1 | CD163 molecule-like 1 | 0.0114409 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0113873 |
| HDAC9 | histone deacetylase 9 | 0.011357 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | 0.0113423 |
| ACTN1 | actinin, alpha 1 | 0.0113208 |
| SKI | SKI proto-oncogene | 0.0112187 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0111867 |
| H1-2 | H1.2 linker histone, cluster member | 0.0111518 |
| AJAP1 | adherens junctions associated protein 1 | 0.0111171 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0109969 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0106802 |
| TOP1 | topoisomerase (DNA) I | 0.0105558 |
| SP100 | SP100 nuclear antigen | 0.0104848 |
| PRKCE | protein kinase C, epsilon | 0.0103234 |
| NEK10 | NIMA-related kinase 10 | 0.0103194 |
| MOK | MOK protein kinase | 0.0103156 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0102236 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0101048 |
| PSPC1 | paraspeckle component 1 | 0.00992729 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00990409 |
| AVIL | advillin | 0.0098811 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.00975545 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.00967895 |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 0.00964206 |
| RBM19 | RNA binding motif protein 19 | 0.00952401 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | 0.00946731 |
| NLK | nemo-like kinase | 0.00942449 |
| DUSP5 | dual specificity phosphatase 5 | 0.00933438 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.00932781 |
| NME7 | NME/NM23 family member 7 | 0.00917977 |
| AMOTL2 | angiomotin like 2 | 0.00914741 |
| TUT7 | terminal uridylyl transferase 7 | 0.00913034 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.00912542 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.00901586 |
| RPS9 | ribosomal protein S9 | 0.00890902 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00887139 |
| CCDC138 | coiled-coil domain containing 138 | 0.00884606 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.00883189 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00881352 |
| PRKCA | protein kinase C, alpha | 0.00878609 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.00876958 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.00865342 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00863176 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00856675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.383651 |
| VIM | vimentin | -0.31323 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.211879 |
| MMP12 | matrix metallopeptidase 12 | -0.133117 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.105445 |
| LSAMP | limbic system-associated membrane protein | -0.101806 |
| RPS6 | ribosomal protein S6 | -0.0997628 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0997129 |
| DTNA | dystrobrevin, alpha | -0.0986676 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0903043 |
| EFNA5 | ephrin-A5 | -0.0865706 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0838337 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0826435 |
| GPC6 | glypican 6 | -0.0806628 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0767792 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0745697 |
| CD109 | CD109 molecule | -0.0736584 |
| LDHA | lactate dehydrogenase A | -0.0709731 |
| ANXA2 | annexin A2 | -0.0659667 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0655869 |
| PTMA | prothymosin, alpha | -0.0653245 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0652246 |
| TMSB10 | thymosin beta 10 | -0.0632633 |
| TPM4 | tropomyosin 4 | -0.0620978 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0529097 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0515136 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0508466 |
| JMJD1C | jumonji domain containing 1C | -0.050004 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0494493 |
| SBF2 | SET binding factor 2 | -0.0492783 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0489562 |
| NDRG1 | N-myc downstream regulated 1 | -0.0486239 |
| TXNRD1 | thioredoxin reductase 1 | -0.0475324 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0474274 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0464525 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0464327 |
| RTN4 | reticulon 4 | -0.0461258 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0447507 |
| PKM | pyruvate kinase, muscle | -0.0437623 |
| PGK1 | phosphoglycerate kinase 1 | -0.0428252 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0418684 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.041664 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0413763 |
| ZNF292 | zinc finger protein 292 | -0.0405341 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0404953 |
| EGR1 | early growth response 1 | -0.0403886 |
| HMGA1 | high mobility group AT-hook 1 | -0.0392475 |
| SPAG9 | sperm associated antigen 9 | -0.0379667 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0378787 |
| CTSB | cathepsin B | -0.0371396 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0368049 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0366552 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0353306 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0352102 |
| FN1 | fibronectin 1 | -0.035118 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0349708 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0346123 |
| CDH13 | cadherin 13 | -0.034545 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0338488 |
| PTK2 | protein tyrosine kinase 2 | -0.0336494 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0332088 |
| KIAA1549L | KIAA1549-like | -0.0329062 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0324042 |
| WDR45B | WD repeat domain 45B | -0.032342 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0323118 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0321079 |
| RPLP1 | ribosomal protein, large, P1 | -0.0320682 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0320044 |
| CD44 | CD44 molecule (Indian blood group) | -0.0320014 |
| JUN | jun proto-oncogene | -0.0319096 |
| YBX3 | Y box binding protein 3 | -0.0319086 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0318714 |
| LIMA1 | LIM domain and actin binding 1 | -0.0317426 |
| HELZ | helicase with zinc finger | -0.0311601 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0310218 |
| FTL | ferritin, light polypeptide | -0.0308859 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0307045 |
| MAP4 | microtubule-associated protein 4 | -0.0304384 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.030269 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0302495 |
| RUNX1 | runt-related transcription factor 1 | -0.0302084 |
| RPS13 | ribosomal protein S13 | -0.0296184 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0295793 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0294335 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0290117 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0289403 |
| CSTB | cystatin B (stefin B) | -0.0286904 |
| RPS8 | ribosomal protein S8 | -0.028581 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0284875 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0283662 |
| RAI14 | retinoic acid induced 14 | -0.0283518 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0280761 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0275571 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0275418 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0273573 |
| ACTG1 | actin gamma 1 | -0.0273446 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0272186 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0271128 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.026772 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0264806 |
