| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.12426 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.108117 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.107614 |
| PTMA | prothymosin, alpha | 0.105061 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.097442 |
| KRT18 | keratin 18, type I | 0.0923305 |
| FAT1 | FAT atypical cadherin 1 | 0.0910554 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0869533 |
| LMO7 | LIM domain 7 | 0.0857196 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0734977 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0684119 |
| MYO1E | myosin IE | 0.0678243 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.066462 |
| AHNAK | AHNAK nucleoprotein | 0.0622587 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0532442 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.049599 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0488881 |
| VCL | vinculin | 0.0461182 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0452982 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0428789 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0427167 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0424163 |
| PLEC | plectin | 0.0418762 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0418562 |
| KRT8 | keratin 8, type II | 0.0404251 |
| EGFR | epidermal growth factor receptor | 0.0401877 |
| TPM4 | tropomyosin 4 | 0.0392396 |
| H1-0 | H1.0 linker histone | 0.0384145 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0384097 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0377802 |
| TFF1 | trefoil factor 1 | 0.0373889 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0370133 |
| ASPH | aspartate beta-hydroxylase | 0.0367312 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0354878 |
| H1-4 | H1.4 linker histone, cluster member | 0.0341609 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0336165 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.032532 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0323159 |
| TMSB4X | thymosin beta 4, X-linked | 0.0315172 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.031155 |
| DSPP | dentin sialophosphoprotein | 0.0303272 |
| HYOU1 | hypoxia up-regulated 1 | 0.0296142 |
| MED13 | mediator complex subunit 13 | 0.0284713 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0283799 |
| MYO5B | myosin VB | 0.0281678 |
| RAB10 | RAB10, member RAS oncogene family | 0.0274924 |
| IER3 | immediate early response 3 | 0.0272477 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.026456 |
| PKP2 | plakophilin 2 | 0.0261127 |
| B2M | beta-2-microglobulin | 0.0255784 |
| ONECUT3 | one cut homeobox 3 | 0.02546 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.025396 |
| SMAD2 | SMAD family member 2 | 0.0252146 |
| USP53 | ubiquitin specific peptidase 53 | 0.0250125 |
| RPL7A | ribosomal protein L7a | 0.0245938 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0245061 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0243046 |
| EPCAM | epithelial cell adhesion molecule | 0.0242789 |
| CD44 | CD44 molecule (Indian blood group) | 0.0242661 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0241097 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0240778 |
| PDE10A | phosphodiesterase 10A | 0.0238823 |
| RPS8 | ribosomal protein S8 | 0.0236883 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.023231 |
| MUC13 | mucin 13, cell surface associated | 0.023083 |
| CLTC | clathrin, heavy chain (Hc) | 0.0230064 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0226444 |
| TPM1 | tropomyosin 1 (alpha) | 0.0225627 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0220365 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0220166 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0218131 |
| BRD2 | bromodomain containing 2 | 0.0217417 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0216791 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0216278 |
| AREG | amphiregulin | 0.0216249 |
| LAMB3 | laminin, beta 3 | 0.0214636 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0213587 |
| RIGI | RNA sensor RIG-I | 0.0213241 |
| LAMA4 | laminin, alpha 4 | 0.0209855 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0200889 |
| GAK | cyclin G associated kinase | 0.0198747 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0198192 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0195369 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0194681 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0191901 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0189554 |
| ACTG1 | actin gamma 1 | 0.0184385 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0181878 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0181516 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0178859 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0178748 |
| CUX1 | cut-like homeobox 1 | 0.0178061 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0176697 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0176342 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0176037 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0173267 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0173265 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0172315 |
| DST | dystonin | 0.0172245 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0171751 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.207782 |
| NPSR1 | neuropeptide S receptor 1 | -0.149408 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.128874 |
| NDRG1 | N-myc downstream regulated 1 | -0.099052 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.08294 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0779302 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0695616 |
| EZR | ezrin | -0.0693421 |
| FLNB | filamin B, beta | -0.0691562 |
| CALB1 | calbindin 1, 28kDa | -0.0691376 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0660229 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0622903 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0617779 |
| ZNF292 | zinc finger protein 292 | -0.0603357 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0591622 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.055664 |
| FAM13A | family with sequence similarity 13, member A | -0.0520835 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0507822 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0484434 |
| GPHN | gephyrin | -0.0483931 |
| PTK2 | protein tyrosine kinase 2 | -0.0468386 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0460326 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0455409 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0436855 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.043631 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0436014 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0429642 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0417313 |
| MED13L | mediator complex subunit 13-like | -0.0411897 |
| GOLGA4 | golgin A4 | -0.0409682 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0408657 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0408168 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0406092 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0401304 |
| ANXA2 | annexin A2 | -0.0392628 |
| RNF217 | ring finger protein 217 | -0.0392332 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0389924 |
| TXNIP | thioredoxin interacting protein | -0.0387446 |
| ITGA6 | integrin, alpha 6 | -0.0387368 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0385498 |
| NFIA | nuclear factor I/A | -0.0383638 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0382986 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0382271 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0381878 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0377345 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0373304 |
| PHKB | phosphorylase kinase, beta | -0.0371113 |
| ITGB4 | integrin, beta 4 | -0.0368636 |
| PTEN | phosphatase and tensin homolog | -0.0360592 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0357847 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0354918 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0354611 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0353899 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0350763 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0345621 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0345185 |
| SBF2 | SET binding factor 2 | -0.0340827 |
| CCNY | cyclin Y | -0.0339058 |
| ERBIN | erbb2 interacting protein | -0.0338583 |
| PHIP | pleckstrin homology domain interacting protein | -0.0335486 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0333993 |
| COG5 | component of oligomeric golgi complex 5 | -0.0328052 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0327401 |
| TNS4 | tensin 4 | -0.0326863 |
| VEGFA | vascular endothelial growth factor A | -0.0324812 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0323702 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0323128 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0320098 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0319567 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.031661 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0314492 |
| PERP | PERP, TP53 apoptosis effector | -0.0312823 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0308279 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0307217 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0307174 |
| FTL | ferritin, light polypeptide | -0.0306895 |
| RIN2 | Ras and Rab interactor 2 | -0.0301541 |
| RPL36 | ribosomal protein L36 | -0.030037 |
| RPS6 | ribosomal protein S6 | -0.0299313 |
| RPL11 | ribosomal protein L11 | -0.0297473 |
| RPLP1 | ribosomal protein, large, P1 | -0.029357 |
| FNBP1L | formin binding protein 1-like | -0.0293109 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0291912 |
| RTN4 | reticulon 4 | -0.0287277 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0286391 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0283761 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0281984 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0280423 |
| POTEF | POTE ankyrin domain family, member F | -0.0278834 |
| TMEM165 | transmembrane protein 165 | -0.0277697 |
| USP34 | ubiquitin specific peptidase 34 | -0.0276291 |
| MUC17 | mucin 17, cell surface associated | -0.0275799 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0275698 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0274326 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0274007 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0273308 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0272999 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.02729 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0270422 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0270323 |
