| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.174211 |
| TMSB4X | thymosin beta 4, X-linked | 0.153826 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.124033 |
| RPS12 | ribosomal protein S12 | 0.10799 |
| DST | dystonin | 0.106522 |
| B2M | beta-2-microglobulin | 0.0860698 |
| CAPRIN2 | caprin family member 2 | 0.0854371 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0843134 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0807114 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0804779 |
| HLA-B | major histocompatibility complex, class I, B | 0.0752303 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0715293 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.07125 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0703057 |
| RPL26 | ribosomal protein L26 | 0.0649739 |
| RUNX1 | runt-related transcription factor 1 | 0.0588746 |
| SET | SET nuclear proto-oncogene | 0.0582764 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0581266 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0581008 |
| RPS3 | ribosomal protein S3 | 0.0565874 |
| TXNIP | thioredoxin interacting protein | 0.0546964 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0525149 |
| RPL37A | ribosomal protein L37a | 0.0513722 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0496587 |
| RPL12 | ribosomal protein L12 | 0.0491075 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.048585 |
| RPL36 | ribosomal protein L36 | 0.0481791 |
| RPL37 | ribosomal protein L37 | 0.0471142 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0467939 |
| TPI1 | triosephosphate isomerase 1 | 0.0467844 |
| RPL23 | ribosomal protein L23 | 0.0458006 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0456853 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0456053 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0455046 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0449653 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0443378 |
| TPM3 | tropomyosin 3 | 0.0443153 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0423743 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0419591 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0411064 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.041065 |
| HLA-A | major histocompatibility complex, class I, A | 0.0399451 |
| ZNF644 | zinc finger protein 644 | 0.0389596 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0377868 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0372624 |
| RPS2 | ribosomal protein S2 | 0.0372359 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0365926 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0363615 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0360261 |
| VCL | vinculin | 0.0353986 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0350431 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0348937 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0348766 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0344954 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0344351 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0341878 |
| RPL34 | ribosomal protein L34 | 0.0340218 |
| OPTN | optineurin | 0.0333344 |
| INTS6 | integrator complex subunit 6 | 0.032764 |
| PLK2 | polo-like kinase 2 | 0.0326397 |
| RPS17 | ribosomal protein S17 | 0.0324681 |
| PLEC | plectin | 0.0319699 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0319214 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0315513 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0315158 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0309503 |
| YME1L1 | YME1-like 1 ATPase | 0.0299204 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0298915 |
| SLK | STE20-like kinase | 0.0298786 |
| KLF6 | Kruppel-like factor 6 | 0.0295338 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0289549 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0289447 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0285808 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0284478 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.028336 |
| GOLGB1 | golgin B1 | 0.028115 |
| S100A9 | S100 calcium binding protein A9 | 0.02777 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0276145 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0273624 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0269565 |
| SQSTM1 | sequestosome 1 | 0.0269158 |
| RPL3 | ribosomal protein L3 | 0.0263667 |
| PFN1 | profilin 1 | 0.0258189 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0253926 |
| LYST | lysosomal trafficking regulator | 0.0250701 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0249382 |
| CPNE1 | copine I | 0.0248642 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0248617 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0247582 |
| CEP290 | centrosomal protein 290kDa | 0.0246727 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0246548 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0245409 |
| SFTPA2 | surfactant protein A2 | 0.0245399 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.024458 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0242943 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0242688 |
| RPL36A | ribosomal protein L36a | 0.024182 |
| GOLGA4 | golgin A4 | 0.0241417 |
| SON | SON DNA binding protein | 0.0241355 |
| IER2 | immediate early response 2 | 0.0240718 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.343737 |
| TXNRD1 | thioredoxin reductase 1 | -0.137811 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.116879 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0896863 |
| RAI1 | retinoic acid induced 1 | -0.0845935 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.073253 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0706274 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0668307 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0620854 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0609327 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0580141 |
| BMERB1 | bMERB domain containing 1 | -0.0568413 |
| FLNB | filamin B, beta | -0.0529477 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0512003 |
| POTEF | POTE ankyrin domain family, member F | -0.0510457 |
| FTL | ferritin, light polypeptide | -0.0498168 |
| EMP1 | epithelial membrane protein 1 | -0.0492229 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0464223 |
| USP34 | ubiquitin specific peptidase 34 | -0.0440449 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.042942 |
| RTN4 | reticulon 4 | -0.0426759 |
| SBF2 | SET binding factor 2 | -0.0412988 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0401126 |
| TP63 | tumor protein p63 | -0.0400884 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0391327 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0386018 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0381728 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0379379 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0376417 |
| UPP1 | uridine phosphorylase 1 | -0.0374644 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0372574 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0370429 |
| RPL5 | ribosomal protein L5 | -0.0369762 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0367624 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0357364 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0351589 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0346165 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0340052 |
| CDCP1 | CUB domain containing protein 1 | -0.033999 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0328741 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0328314 |
| PRDX1 | peroxiredoxin 1 | -0.0318951 |
| EHBP1 | EH domain binding protein 1 | -0.0310803 |
| TAPBP | TAP binding protein (tapasin) | -0.0309613 |
| ANXA1 | annexin A1 | -0.0306672 |
| CD44 | CD44 molecule (Indian blood group) | -0.0302768 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0302453 |
| NAV2 | neuron navigator 2 | -0.0301051 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0293465 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0286534 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0283735 |
| S100A10 | S100 calcium binding protein A10 | -0.0282337 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0278624 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0277558 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0273597 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0272333 |
| RBM25 | RNA binding motif protein 25 | -0.026927 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0269042 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0263591 |
| AK4 | adenylate kinase 4 | -0.0262415 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0257572 |
| CEP170 | centrosomal protein 170kDa | -0.025335 |
| DNER | delta/notch-like EGF repeat containing | -0.0248725 |
| LOXL2 | lysyl oxidase-like 2 | -0.0248723 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0247467 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0247118 |
| ACTG1 | actin gamma 1 | -0.0244622 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0244035 |
| MKI67 | marker of proliferation Ki-67 | -0.0243368 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0242592 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0239534 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0238426 |
| GAN | gigaxonin | -0.0237092 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0234795 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0231109 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0227673 |
| PODXL | podocalyxin-like | -0.0227396 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0227367 |
| NBEAL1 | neurobeachin-like 1 | -0.0225572 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0225306 |
| HMOX1 | heme oxygenase 1 | -0.0224528 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0224116 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0219032 |
| NF1 | neurofibromin 1 | -0.0217948 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0217088 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0217024 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0215887 |
| PGK1 | phosphoglycerate kinase 1 | -0.021552 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0214842 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0214757 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0213812 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0213234 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0211351 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0211021 |
| RLF | rearranged L-myc fusion | -0.0210365 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0210358 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0206776 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0205065 |
| YBX1 | Y box binding protein 1 | -0.020417 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0204155 |
