| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0804459 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0759804 |
| GLCCI1 | glucocorticoid induced 1 | 0.0750381 |
| FAM20C | family with sequence similarity 20, member C | 0.0657988 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0600675 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0600602 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0600239 |
| CD44 | CD44 molecule (Indian blood group) | 0.0598297 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0563149 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0557135 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0553525 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0484142 |
| IFI44L | interferon-induced protein 44-like | 0.0441305 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0437393 |
| SMAD3 | SMAD family member 3 | 0.0436077 |
| HMGA2 | high mobility group AT-hook 2 | 0.0433096 |
| STK38L | serine/threonine kinase 38 like | 0.041297 |
| MT2A | metallothionein 2A | 0.0398634 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0387459 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0383619 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0381279 |
| AHNAK | AHNAK nucleoprotein | 0.0375209 |
| ASPH | aspartate beta-hydroxylase | 0.0358838 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0345351 |
| SEPTIN9 | septin 9 | 0.0344289 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0327521 |
| ECE1 | endothelin converting enzyme 1 | 0.0325471 |
| FTL | ferritin, light polypeptide | 0.0322677 |
| ANGPTL4 | angiopoietin-like 4 | 0.0320084 |
| EFNA5 | ephrin-A5 | 0.0309652 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0305757 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0282889 |
| PKM | pyruvate kinase, muscle | 0.0280155 |
| INTS6 | integrator complex subunit 6 | 0.0278997 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.027726 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0269273 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0267493 |
| RPLP1 | ribosomal protein, large, P1 | 0.0265 |
| PTK2 | protein tyrosine kinase 2 | 0.0260406 |
| RPS19 | ribosomal protein S19 | 0.0259943 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0255961 |
| RPS8 | ribosomal protein S8 | 0.0253715 |
| MYO10 | myosin X | 0.0253308 |
| NAV2 | neuron navigator 2 | 0.0250106 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0248331 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0244469 |
| ACTN4 | actinin, alpha 4 | 0.0243306 |
| KSR1 | kinase suppressor of ras 1 | 0.0242378 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0239455 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0236805 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0234816 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0234038 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0233908 |
| PLEC | plectin | 0.0231018 |
| RPL23 | ribosomal protein L23 | 0.0228797 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0226917 |
| NRP1 | neuropilin 1 | 0.0224492 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0224181 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0223454 |
| NAV1 | neuron navigator 1 | 0.0223404 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0222952 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0222545 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0222092 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0218848 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0215087 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0213816 |
| ATXN1 | ataxin 1 | 0.021215 |
| PRSS3 | protease, serine, 3 | 0.0208937 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0205501 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0203421 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0203028 |
| SQSTM1 | sequestosome 1 | 0.0198412 |
| RPL34 | ribosomal protein L34 | 0.0198391 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0197315 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0194587 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0192301 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0188943 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0186487 |
| TOP1 | topoisomerase (DNA) I | 0.0185788 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0182359 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0181896 |
| RPS17 | ribosomal protein S17 | 0.0181685 |
| TGM2 | transglutaminase 2 | 0.0180689 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0179391 |
| PCDH7 | protocadherin 7 | 0.0179147 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0179064 |
| RPL37A | ribosomal protein L37a | 0.0178499 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0178461 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0178216 |
| WWOX | WW domain containing oxidoreductase | 0.0176448 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0174855 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0172804 |
| SP100 | SP100 nuclear antigen | 0.0172633 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0168747 |
| FHL2 | four and a half LIM domains 2 | 0.0165915 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0165062 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0164806 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0163232 |
| ANXA10 | annexin A10 | 0.0162778 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0162024 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.17305 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.144562 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.138232 |
| GOLGA4 | golgin A4 | -0.125494 |
| USP34 | ubiquitin specific peptidase 34 | -0.092623 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0857908 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.070589 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0684537 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0684521 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0665185 |
| GPC6 | glypican 6 | -0.0657101 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0619825 |
| PCBP2 | poly(rC) binding protein 2 | -0.0536868 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0531007 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0530307 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0525682 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0521875 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0511093 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0510596 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0494641 |
| SEC24A | SEC24 family member A | -0.0491309 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0489053 |
| RBM39 | RNA binding motif protein 39 | -0.0479736 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0463218 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0462267 |
| ARF4 | ADP-ribosylation factor 4 | -0.0461351 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0460707 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0449995 |
| MEF2A | myocyte enhancer factor 2A | -0.0426356 |
| SRP54 | signal recognition particle 54kDa | -0.0417388 |
| RUNX2 | runt-related transcription factor 2 | -0.0416652 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.040475 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0399943 |
| LOX | lysyl oxidase | -0.0396647 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0393572 |
| COPA | coatomer protein complex, subunit alpha | -0.0392232 |
| ZNF292 | zinc finger protein 292 | -0.0389781 |
| FAM13A | family with sequence similarity 13, member A | -0.0388378 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0382178 |
| RAI14 | retinoic acid induced 14 | -0.0381574 |
| ETV6 | ets variant 6 | -0.0381215 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.037998 |
| NF1 | neurofibromin 1 | -0.0378604 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.037806 |
| EGR1 | early growth response 1 | -0.0377939 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.037407 |
| DENND4A | DENN/MADD domain containing 4A | -0.037328 |
| OSMR | oncostatin M receptor | -0.0372608 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0368938 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0366009 |
| TMEM165 | transmembrane protein 165 | -0.0363141 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0361639 |
| SBF2 | SET binding factor 2 | -0.0360703 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0358347 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0356161 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0355444 |
| TBC1D15 | TBC1 domain family, member 15 | -0.0353883 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.035376 |
| FNIP1 | folliculin interacting protein 1 | -0.0351237 |
| SPAG9 | sperm associated antigen 9 | -0.0342431 |
| MORF4L2 | mortality factor 4 like 2 | -0.0332104 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0330781 |
| LMAN1 | lectin, mannose-binding, 1 | -0.032174 |
| EXOC4 | exocyst complex component 4 | -0.0317632 |
| HDAC9 | histone deacetylase 9 | -0.031486 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0312613 |
| COG5 | component of oligomeric golgi complex 5 | -0.0311671 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0308863 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0308618 |
| YME1L1 | YME1-like 1 ATPase | -0.0306021 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0304215 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0303921 |
| SYT1 | synaptotagmin I | -0.0303838 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.030348 |
| LRRC49 | leucine rich repeat containing 49 | -0.0303046 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.030279 |
| SYAP1 | synapse associated protein 1 | -0.0302639 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0300902 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0299371 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0299123 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0293779 |
| AAK1 | AP2 associated kinase 1 | -0.0292982 |
| DYM | dymeclin | -0.0291869 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0290075 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0290047 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0285445 |
| ATP13A3 | ATPase type 13A3 | -0.0284275 |
| CALU | calumenin | -0.0282058 |
| EREG | epiregulin | -0.0279111 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0278823 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0275825 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0271651 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0270854 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0269734 |
| ZFP91 | ZFP91 zinc finger protein | -0.026575 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0265348 |
| SETD5 | SET domain containing 5 | -0.0265238 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0264356 |
| TMEM263 | transmembrane protein 263 | -0.0263698 |
| VRK2 | vaccinia related kinase 2 | -0.0263598 |
