| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.184693 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.172465 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.155545 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0834039 |
| MCL1 | myeloid cell leukemia 1 | 0.0691648 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.062108 |
| TPI1 | triosephosphate isomerase 1 | 0.0615629 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.059471 |
| TPM3 | tropomyosin 3 | 0.0589615 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0587519 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0536935 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0501263 |
| HOMER1 | homer scaffolding protein 1 | 0.0494402 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0492113 |
| INTS6 | integrator complex subunit 6 | 0.0488821 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0484525 |
| KRT18 | keratin 18, type I | 0.0475691 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0475524 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.045164 |
| TPM2 | tropomyosin 2 (beta) | 0.0427671 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.041528 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0414436 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0404634 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0403763 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0401053 |
| PLEC | plectin | 0.0400367 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0394106 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0391079 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0388611 |
| RPL3 | ribosomal protein L3 | 0.0381937 |
| CPNE1 | copine I | 0.0380391 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0379798 |
| RPL23 | ribosomal protein L23 | 0.0378535 |
| RPS3 | ribosomal protein S3 | 0.0375094 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0358818 |
| CTTN | cortactin | 0.0357731 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0354261 |
| BRD2 | bromodomain containing 2 | 0.033403 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0333861 |
| ASPH | aspartate beta-hydroxylase | 0.0332597 |
| DSPP | dentin sialophosphoprotein | 0.0327439 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0319626 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0317645 |
| VCP | valosin containing protein | 0.0317401 |
| TMSB10 | thymosin beta 10 | 0.0310845 |
| DST | dystonin | 0.0309091 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0309064 |
| PTMA | prothymosin, alpha | 0.0304349 |
| YBX3 | Y box binding protein 3 | 0.0292614 |
| CLTC | clathrin, heavy chain (Hc) | 0.0290672 |
| ACTG1 | actin gamma 1 | 0.0288316 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0285453 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0282087 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0279403 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0279051 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0278186 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0275445 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0264339 |
| STK4 | serine/threonine kinase 4 | 0.0261805 |
| CEP250 | centrosomal protein 250kDa | 0.0261793 |
| CLTA | clathrin, light chain A | 0.0257865 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0256763 |
| STC1 | stanniocalcin 1 | 0.0253824 |
| IER2 | immediate early response 2 | 0.0251498 |
| TRIM59 | tripartite motif containing 59 | 0.0250166 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0249698 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0249556 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.02462 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0241736 |
| SET | SET nuclear proto-oncogene | 0.0241009 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.023871 |
| RPS8 | ribosomal protein S8 | 0.0237248 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0235991 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0235569 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0233986 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0233569 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0233219 |
| AHNAK | AHNAK nucleoprotein | 0.0232028 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0231976 |
| CAVIN1 | caveolae associated protein 1 | 0.0230821 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0228479 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0228165 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0226641 |
| SRSF7 | serine/arginine-rich splicing factor 7 | 0.0223757 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0222823 |
| RPL26 | ribosomal protein L26 | 0.0219934 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0219919 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0219853 |
| NONO | non-POU domain containing, octamer-binding | 0.0219795 |
| RPS21 | ribosomal protein S21 | 0.0218808 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0216865 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0216788 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0216612 |
| RPL41 | ribosomal protein L41 | 0.0216429 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.021568 |
| RPS2 | ribosomal protein S2 | 0.0213175 |
| AEBP2 | AE binding protein 2 | 0.0212228 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0206007 |
| RPL7A | ribosomal protein L7a | 0.0205904 |
| RPS17 | ribosomal protein S17 | 0.0202825 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.212735 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0933493 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0851765 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0766271 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0743413 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0724377 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0722728 |
| RAD51B | RAD51 paralog B | -0.0722526 |
| EGR1 | early growth response 1 | -0.0720025 |
| POTEF | POTE ankyrin domain family, member F | -0.0673298 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0621086 |
| TMEM165 | transmembrane protein 165 | -0.0606843 |
| RSF1 | remodeling and spacing factor 1 | -0.0591964 |
| PDE10A | phosphodiesterase 10A | -0.0582514 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.055795 |
| OSMR | oncostatin M receptor | -0.0546714 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0541638 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0540061 |
| PTK2 | protein tyrosine kinase 2 | -0.0520702 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0504176 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0477672 |
| SBF2 | SET binding factor 2 | -0.0469518 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0465746 |
| NF1 | neurofibromin 1 | -0.0442498 |
| EXOC4 | exocyst complex component 4 | -0.0434959 |
| LATS2 | large tumor suppressor kinase 2 | -0.0434001 |
| TAPBP | TAP binding protein (tapasin) | -0.042883 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0425462 |
| BBX | bobby sox homolog (Drosophila) | -0.0420089 |
| USP34 | ubiquitin specific peptidase 34 | -0.0419397 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0419138 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0413808 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0409923 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0406 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0388189 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0383111 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0379884 |
| IGF2 | insulin-like growth factor 2 | -0.0379596 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.037559 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0374933 |
| ATXN1 | ataxin 1 | -0.0368958 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0353963 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0353248 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0351573 |
| SMAD3 | SMAD family member 3 | -0.034902 |
| ZNF292 | zinc finger protein 292 | -0.0348522 |
| PHF21A | PHD finger protein 21A | -0.0346881 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0344957 |
| BSG | basigin (Ok blood group) | -0.0342913 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0341338 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0340032 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0335221 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0334675 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0330796 |
| EGFR | epidermal growth factor receptor | -0.0329569 |
| SETD5 | SET domain containing 5 | -0.0324478 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.032284 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0320756 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0320642 |
| THOC2 | THO complex 2 | -0.0317381 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.031402 |
| NOP58 | NOP58 ribonucleoprotein | -0.0313353 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0306337 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0306157 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0305288 |
| NCOR1 | nuclear receptor corepressor 1 | -0.030401 |
| PFN1 | profilin 1 | -0.030287 |
| COG5 | component of oligomeric golgi complex 5 | -0.0301106 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0300874 |
| TXNRD1 | thioredoxin reductase 1 | -0.0298864 |
| SRPK1 | SRSF protein kinase 1 | -0.0298485 |
| MMP12 | matrix metallopeptidase 12 | -0.029583 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0295753 |
| HMGA2 | high mobility group AT-hook 2 | -0.0295742 |
| NBAS | neuroblastoma amplified sequence | -0.0293635 |
| WASF2 | WAS protein family, member 2 | -0.0288953 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0285524 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0282927 |
| RNF38 | ring finger protein 38 | -0.0282814 |
| GOLGA4 | golgin A4 | -0.0281809 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0281782 |
| COPA | coatomer protein complex, subunit alpha | -0.0278492 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.02764 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0274144 |
| TFG | TRK-fused gene | -0.0274128 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0272988 |
| HMGA1 | high mobility group AT-hook 1 | -0.0272352 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0271609 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0269602 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0262413 |
| PLSCR1 | phospholipid scramblase 1 | -0.02617 |
| EHBP1 | EH domain binding protein 1 | -0.0261515 |
| CCNL1 | cyclin L1 | -0.0256514 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.025624 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0256101 |
| ATXN2 | ataxin 2 | -0.0255376 |
| ICAM1 | intercellular adhesion molecule 1 | -0.025504 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0254885 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0251119 |
| FOXJ3 | forkhead box J3 | -0.0250253 |
