| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL3A1 | collagen, type III, alpha 1 | 0.0694617 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0500507 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.043935 |
| TENM3 | teneurin transmembrane protein 3 | 0.041587 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0368992 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0368567 |
| MED13L | mediator complex subunit 13-like | 0.0365247 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0350319 |
| MED12L | mediator complex subunit 12-like | 0.0346626 |
| SQSTM1 | sequestosome 1 | 0.0339899 |
| PTMA | prothymosin, alpha | 0.032261 |
| USP53 | ubiquitin specific peptidase 53 | 0.0313148 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0312591 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0303998 |
| H1-0 | H1.0 linker histone | 0.0294766 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0291818 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.029051 |
| LYST | lysosomal trafficking regulator | 0.0289045 |
| SEPTIN7 | septin 7 | 0.0287592 |
| EPHA5 | EPH receptor A5 | 0.0284311 |
| DIDO1 | death inducer-obliterator 1 | 0.0273863 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0272092 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0260054 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0255042 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0254419 |
| ZNF385D | zinc finger protein 385D | 0.0253139 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0248248 |
| PEG10 | paternally expressed 10 | 0.0244958 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0243509 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0242769 |
| HMCN1 | hemicentin 1 | 0.0237683 |
| UTRN | utrophin | 0.0236095 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0235279 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0234081 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0232196 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0229817 |
| ASPH | aspartate beta-hydroxylase | 0.022528 |
| PCBP3 | poly(rC) binding protein 3 | 0.0223401 |
| SAMD11 | sterile alpha motif domain containing 11 | 0.0221552 |
| FMNL2 | formin-like 2 | 0.0216701 |
| PHF3 | PHD finger protein 3 | 0.0213953 |
| VCL | vinculin | 0.021167 |
| RPL37A | ribosomal protein L37a | 0.0209482 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0208898 |
| CCDC91 | coiled-coil domain containing 91 | 0.0207884 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0205719 |
| H1-4 | H1.4 linker histone, cluster member | 0.0205574 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0205572 |
| TMSB4X | thymosin beta 4, X-linked | 0.0200574 |
| RNF216 | ring finger protein 216 | 0.0199691 |
| PGPEP1L | pyroglutamyl-peptidase I-like | 0.0199521 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0196285 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0196231 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0196188 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0195255 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0194807 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0192825 |
| CAVIN1 | caveolae associated protein 1 | 0.0192132 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0190553 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0189931 |
| TLK1 | tousled-like kinase 1 | 0.0189731 |
| CCDC138 | coiled-coil domain containing 138 | 0.01895 |
| NBEA | neurobeachin | 0.0189385 |
| PHF14 | PHD finger protein 14 | 0.0188727 |
| SRP54 | signal recognition particle 54kDa | 0.018785 |
| KIF1B | kinesin family member 1B | 0.0187034 |
| RRBP1 | ribosome binding protein 1 | 0.0185952 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0185259 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0183305 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0182004 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0181912 |
| PRR16 | proline rich 16 | 0.018058 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0178275 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0177597 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.0177243 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0177123 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0176358 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0176111 |
| OTOGL | otogelin-like | 0.017583 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0174702 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0173978 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0173839 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0173533 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0172108 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.017202 |
| ZNF638 | zinc finger protein 638 | 0.0171631 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0170896 |
| TPTE | transmembrane phosphatase with tensin homology | 0.0170607 |
| GPC6 | glypican 6 | 0.0169485 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0169421 |
| TOP1 | topoisomerase (DNA) I | 0.0168791 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0168738 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0167317 |
| FOXN3 | forkhead box N3 | 0.0166355 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0166227 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0166066 |
| UVRAG | UV radiation resistance associated | 0.0164268 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0164155 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0163291 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0163107 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.1371 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0909878 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0837067 |
| TMSB10 | thymosin beta 10 | -0.082788 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.079926 |
| NRG1 | neuregulin 1 | -0.0795026 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0764956 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0747879 |
| ITGAV | integrin, alpha V | -0.0612777 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0608775 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0565277 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0554602 |
| PLPP1 | phospholipid phosphatase 1 | -0.0535774 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0531489 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0529447 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0527947 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0521896 |
| RPS6 | ribosomal protein S6 | -0.0500394 |
| PCDH9 | protocadherin 9 | -0.0490851 |
| PHIP | pleckstrin homology domain interacting protein | -0.0473415 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0468049 |
| PRTG | protogenin | -0.046594 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0451365 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0442057 |
| POTEF | POTE ankyrin domain family, member F | -0.0440904 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0426993 |
| ACTG1 | actin gamma 1 | -0.0426099 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0421542 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0413552 |
| RPS16 | ribosomal protein S16 | -0.0406566 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0406477 |
| RPL11 | ribosomal protein L11 | -0.0394739 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0387605 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0384674 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0384114 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0380235 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0362767 |
| FIGN | fidgetin | -0.0353025 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0349051 |
| CCN2 | cellular communication network factor 2 | -0.0341752 |
| NTM | neurotrimin | -0.0332692 |
| CENPE | centromere protein E, 312kDa | -0.0331658 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0329525 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0329208 |
| TUBA1B | tubulin, alpha 1b | -0.0323333 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0320382 |
| RBM20 | RNA binding motif protein 20 | -0.0319937 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0319931 |
| ANK2 | ankyrin 2, neuronal | -0.031954 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0317613 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0316881 |
| DACH1 | dachshund family transcription factor 1 | -0.0315841 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0311538 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0307324 |
| FOXP2 | forkhead box P2 | -0.0306883 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0302991 |
| MKI67 | marker of proliferation Ki-67 | -0.0302452 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0295625 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0295529 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0291918 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0291345 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0289412 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0289184 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0288828 |
| KPNB1 | karyopherin (importin) beta 1 | -0.028532 |
| CBX3 | chromobox homolog 3 | -0.0281163 |
| VIM | vimentin | -0.0280486 |
| RTN4 | reticulon 4 | -0.0280035 |
| SETD5 | SET domain containing 5 | -0.0277702 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0276927 |
| PFN1 | profilin 1 | -0.0276574 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0272018 |
| DMD | dystrophin | -0.0268291 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0267899 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0267757 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0267145 |
| TUT4 | terminal uridylyl transferase 4 | -0.0263135 |
| NUP153 | nucleoporin 153kDa | -0.0261666 |
| LRRC4C | leucine rich repeat containing 4C | -0.0261002 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0259823 |
| SIK2 | salt-inducible kinase 2 | -0.0259357 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0258039 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0256096 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0253954 |
| WASF2 | WAS protein family, member 2 | -0.0248826 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0248403 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0247076 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.024671 |
| RPL30 | ribosomal protein L30 | -0.0245536 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0244197 |
| EMP1 | epithelial membrane protein 1 | -0.0242725 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.0242266 |
| THBS1 | thrombospondin 1 | -0.024107 |
| SRPK2 | SRSF protein kinase 2 | -0.0240602 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0237703 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0236987 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0235896 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0235896 |
| TCF12 | transcription factor 12 | -0.0235245 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | -0.0233044 |
