| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.188589 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.168413 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.152694 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0981409 |
| PTMA | prothymosin, alpha | 0.097047 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0821304 |
| RPS12 | ribosomal protein S12 | 0.0791928 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0778074 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0766032 |
| RPS3 | ribosomal protein S3 | 0.0759067 |
| RPS2 | ribosomal protein S2 | 0.0732226 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0713095 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0704481 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0690388 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0675306 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0649529 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.058863 |
| INTS6 | integrator complex subunit 6 | 0.0574804 |
| CENPF | centromere protein F, 350/400kDa | 0.0574784 |
| MT2A | metallothionein 2A | 0.0567302 |
| PLEC | plectin | 0.0546326 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0544668 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0542077 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0532441 |
| SET | SET nuclear proto-oncogene | 0.0528026 |
| B2M | beta-2-microglobulin | 0.0519812 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0511611 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0509566 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0504681 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0503031 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0477311 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0460433 |
| RPL37A | ribosomal protein L37a | 0.0438694 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0437548 |
| SEPTIN9 | septin 9 | 0.0435347 |
| MSN | moesin | 0.0435231 |
| RPS17 | ribosomal protein S17 | 0.0432933 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0428034 |
| RPL23 | ribosomal protein L23 | 0.0426834 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0423892 |
| SPAG9 | sperm associated antigen 9 | 0.0418544 |
| RPS8 | ribosomal protein S8 | 0.0406692 |
| TPM3 | tropomyosin 3 | 0.0388315 |
| ANGPTL4 | angiopoietin-like 4 | 0.0378523 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0377936 |
| GOLGB1 | golgin B1 | 0.0374916 |
| ASPH | aspartate beta-hydroxylase | 0.0371478 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0366796 |
| OGA | O-GlcNAcase | 0.0366167 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0364907 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0362473 |
| DSCAM | Down syndrome cell adhesion molecule | 0.03615 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0359597 |
| BRD2 | bromodomain containing 2 | 0.0358172 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.03553 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.0352306 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0351986 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0347104 |
| SEPTIN7 | septin 7 | 0.0345997 |
| PRELID2 | PRELI domain containing 2 | 0.0344435 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0340132 |
| RPL11 | ribosomal protein L11 | 0.0338148 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0331753 |
| RRM2 | ribonucleotide reductase M2 | 0.0329898 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0327276 |
| TPR | translocated promoter region, nuclear basket protein | 0.0322739 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0320961 |
| CALR | calreticulin | 0.0319791 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.031765 |
| AFDN | afadin, adherens junction formation factor | 0.0317479 |
| MCL1 | myeloid cell leukemia 1 | 0.0302213 |
| CTBP2 | C-terminal binding protein 2 | 0.029842 |
| VCL | vinculin | 0.029839 |
| TPM2 | tropomyosin 2 (beta) | 0.0295944 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0295365 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.029428 |
| RPL12 | ribosomal protein L12 | 0.0292672 |
| RPS19 | ribosomal protein S19 | 0.029177 |
| RACK1 | receptor for activated C kinase 1 | 0.0291 |
| SMC4 | structural maintenance of chromosomes 4 | 0.028982 |
| RPL3 | ribosomal protein L3 | 0.0286676 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0286645 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0286045 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0285482 |
| RPL26 | ribosomal protein L26 | 0.0285102 |
| HMGB2 | high mobility group box 2 | 0.0283893 |
| RPL35A | ribosomal protein L35a | 0.0277632 |
| CANX | calnexin | 0.0274557 |
| RPLP2 | ribosomal protein, large, P2 | 0.0273635 |
| TPI1 | triosephosphate isomerase 1 | 0.0271848 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0270431 |
| CPNE1 | copine I | 0.0265185 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0263693 |
| HYOU1 | hypoxia up-regulated 1 | 0.0262938 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0262269 |
| ENO1 | enolase 1, (alpha) | 0.0260832 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0259414 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0259208 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0258868 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.025615 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.223074 |
| VIM | vimentin | -0.197943 |
| RPS16 | ribosomal protein S16 | -0.106335 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.10441 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.10142 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.100816 |
| CD44 | CD44 molecule (Indian blood group) | -0.0810171 |
| ZFP36 | ZFP36 ring finger protein | -0.071634 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0619385 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.058446 |
| EGFR | epidermal growth factor receptor | -0.0581322 |
| TMEM123 | transmembrane protein 123 | -0.0579843 |
| RTN4 | reticulon 4 | -0.0575461 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0567315 |
| ANXA2 | annexin A2 | -0.0548947 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0544797 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0514113 |
| CTSD | cathepsin D | -0.048517 |
| SBF2 | SET binding factor 2 | -0.0464643 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0447898 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0388775 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0380533 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0377248 |
| ZNF780B | zinc finger protein 780B | -0.0366959 |
| MAP1B | microtubule-associated protein 1B | -0.0339031 |
| EGR1 | early growth response 1 | -0.0310008 |
| FHL2 | four and a half LIM domains 2 | -0.0309201 |
| CDCP1 | CUB domain containing protein 1 | -0.0306973 |
| TMEM41B | transmembrane protein 41B | -0.0302832 |
| TAPBP | TAP binding protein (tapasin) | -0.0287159 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0285364 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0281763 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0269466 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0268534 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0262237 |
| ACTG1 | actin gamma 1 | -0.026178 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0255917 |
| FBXO17 | F-box protein 17 | -0.0254894 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0254486 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0252786 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0248071 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.024422 |
| AFAP1 | actin filament associated protein 1 | -0.0243792 |
| POTEF | POTE ankyrin domain family, member F | -0.0243111 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0242466 |
| OSMR | oncostatin M receptor | -0.02343 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0232801 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.0232054 |
| ATG7 | autophagy related 7 | -0.0230515 |
| EHBP1 | EH domain binding protein 1 | -0.0228763 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0222574 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0220697 |
| PTEN | phosphatase and tensin homolog | -0.0218858 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0218429 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0213343 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0212365 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0211366 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0210289 |
| JMJD1C | jumonji domain containing 1C | -0.0206223 |
| HMGA1 | high mobility group AT-hook 1 | -0.0205439 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0204667 |
| MEF2A | myocyte enhancer factor 2A | -0.0201192 |
| RASAL2 | RAS protein activator like 2 | -0.0198813 |
| WASF2 | WAS protein family, member 2 | -0.0195935 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0194221 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0194096 |
| PHF14 | PHD finger protein 14 | -0.0190817 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0189141 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0187538 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0187302 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0178837 |
| PDE10A | phosphodiesterase 10A | -0.0178663 |
| CD109 | CD109 molecule | -0.0177827 |
| RIN2 | Ras and Rab interactor 2 | -0.0177154 |
| HMGA2 | high mobility group AT-hook 2 | -0.0175963 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0175222 |
| REEP3 | receptor accessory protein 3 | -0.0170495 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0169786 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0168447 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0164614 |
| CD47 | CD47 molecule | -0.0164138 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0162518 |
| VMP1 | vacuole membrane protein 1 | -0.0160366 |
| MYADM | myeloid-associated differentiation marker | -0.0160331 |
| ZNF546 | zinc finger protein 546 | -0.01597 |
| AXL | AXL receptor tyrosine kinase | -0.0155906 |
| CDK19 | cyclin-dependent kinase 19 | -0.0155461 |
| H1-0 | H1.0 linker histone | -0.0152098 |
| RPL39 | ribosomal protein L39 | -0.0151782 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0151703 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0151481 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0151128 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0146561 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0146417 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -0.0145889 |
| RPS24 | ribosomal protein S24 | -0.0144034 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0143539 |
| TMEM165 | transmembrane protein 165 | -0.014264 |
| EFNA5 | ephrin-A5 | -0.0141896 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0141558 |
