| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.126693 |
| LAMB3 | laminin, beta 3 | 0.112677 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.111423 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0991837 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0895213 |
| LMO7 | LIM domain 7 | 0.0855611 |
| LAMC2 | laminin, gamma 2 | 0.0847226 |
| SMAD3 | SMAD family member 3 | 0.0839353 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.08182 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0724541 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0644278 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0642786 |
| NAV2 | neuron navigator 2 | 0.0630533 |
| TJP1 | tight junction protein 1 | 0.0620266 |
| MYO5B | myosin VB | 0.0606934 |
| PLEC | plectin | 0.0564445 |
| SQSTM1 | sequestosome 1 | 0.0557256 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0541173 |
| AFDN | afadin, adherens junction formation factor | 0.0520889 |
| DSPP | dentin sialophosphoprotein | 0.0505516 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0494887 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0478983 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0445267 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0442911 |
| SVIL | supervillin | 0.0433802 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0423012 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0411464 |
| HDAC9 | histone deacetylase 9 | 0.0400683 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0394099 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0387944 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.038685 |
| FMNL2 | formin-like 2 | 0.038434 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0383063 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0373017 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0371557 |
| ACTN1 | actinin, alpha 1 | 0.0370546 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0366626 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0364508 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0361195 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0352888 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0352801 |
| CPNE1 | copine I | 0.0349619 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0346091 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0344878 |
| EFNB2 | ephrin-B2 | 0.0338004 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0337746 |
| GOLGB1 | golgin B1 | 0.0333098 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0332838 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0332212 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0329528 |
| VCL | vinculin | 0.0327685 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0326544 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0325892 |
| DST | dystonin | 0.0320434 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0319211 |
| AHNAK | AHNAK nucleoprotein | 0.0318554 |
| FLNA | filamin A, alpha | 0.0310375 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0308384 |
| SIK3 | SIK family kinase 3 | 0.0308353 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0300949 |
| FAM107B | family with sequence similarity 107, member B | 0.0296809 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0296671 |
| TLE4 | transducin-like enhancer of split 4 | 0.029267 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0292565 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0291051 |
| DUSP10 | dual specificity phosphatase 10 | 0.0289378 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0286635 |
| AEBP2 | AE binding protein 2 | 0.0284641 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0284229 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0281636 |
| RNF213 | ring finger protein 213 | 0.0281293 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.027823 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0277672 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0276612 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0273487 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0267918 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0265413 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0265294 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.026457 |
| BRD2 | bromodomain containing 2 | 0.0262187 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0259162 |
| SEPTIN9 | septin 9 | 0.0258522 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0258181 |
| ATF3 | activating transcription factor 3 | 0.0258038 |
| IRS2 | insulin receptor substrate 2 | 0.0257569 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0254826 |
| KLC1 | kinesin light chain 1 | 0.0253407 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0252178 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0251458 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0250928 |
| CAPRIN2 | caprin family member 2 | 0.0248905 |
| RBM39 | RNA binding motif protein 39 | 0.024762 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0243548 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0242632 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0242367 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0241581 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0234457 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0233816 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.023326 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0232911 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.334904 |
| MUC4 | mucin 4, cell surface associated | -0.162007 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.126481 |
| HMGA1 | high mobility group AT-hook 1 | -0.108804 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0985505 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0828964 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0816603 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0790149 |
| POTEF | POTE ankyrin domain family, member F | -0.0723544 |
| LDHA | lactate dehydrogenase A | -0.0711063 |
| ANXA2 | annexin A2 | -0.069235 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.068191 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0628084 |
| MUC16 | mucin 16, cell surface associated | -0.0627826 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0613855 |
| RPS6 | ribosomal protein S6 | -0.0596816 |
| TPM4 | tropomyosin 4 | -0.0581811 |
| PLAT | plasminogen activator, tissue | -0.0567592 |
| TMEM123 | transmembrane protein 123 | -0.0559616 |
| PTMA | prothymosin, alpha | -0.0559597 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0544269 |
| KRT7 | keratin 7, type II | -0.0524001 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0500897 |
| TMSB10 | thymosin beta 10 | -0.0489686 |
| DSG2 | desmoglein 2 | -0.0489072 |
| S100A6 | S100 calcium binding protein A6 | -0.0482262 |
| TGM2 | transglutaminase 2 | -0.0477991 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0471731 |
| KRT19 | keratin 19, type I | -0.0467462 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0460232 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0456314 |
| OSMR | oncostatin M receptor | -0.0456059 |
| TAPBP | TAP binding protein (tapasin) | -0.044444 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0436936 |
| TC2N | tandem C2 domains, nuclear | -0.0430956 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0428575 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0413539 |
| CD2AP | CD2-associated protein | -0.0408556 |
| FOSL1 | FOS-like antigen 1 | -0.0397026 |
| HLA-E | major histocompatibility complex, class I, E | -0.0393712 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0392322 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0392211 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0384087 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0380522 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0378301 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0373836 |
| RIOK3 | RIO kinase 3 | -0.0372904 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0372692 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0366401 |
| HLA-B | major histocompatibility complex, class I, B | -0.0358349 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0352049 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.034555 |
| RPS24 | ribosomal protein S24 | -0.0335703 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0333009 |
| KRT17 | keratin 17, type I | -0.0318193 |
| HLA-C | major histocompatibility complex, class I, C | -0.0317042 |
| CDCP1 | CUB domain containing protein 1 | -0.0309867 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0307577 |
| RPLP1 | ribosomal protein, large, P1 | -0.030736 |
| ANLN | anillin, actin binding protein | -0.0307281 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0293042 |
| WDR45B | WD repeat domain 45B | -0.0288833 |
| RPL35A | ribosomal protein L35a | -0.0284632 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0282916 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.028246 |
| ATP11A | ATPase, class VI, type 11A | -0.0281831 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.028138 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0281318 |
| WWC1 | WW and C2 domain containing 1 | -0.0280969 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0278729 |
| RACK1 | receptor for activated C kinase 1 | -0.0278503 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0277143 |
| RPL28 | ribosomal protein L28 | -0.0275478 |
| NDRG1 | N-myc downstream regulated 1 | -0.0272776 |
| RPS23 | ribosomal protein S23 | -0.0272442 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0271692 |
| EGR1 | early growth response 1 | -0.0269323 |
| HLA-A | major histocompatibility complex, class I, A | -0.0269134 |
| NRP1 | neuropilin 1 | -0.0267916 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0263818 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0262812 |
| RPS15 | ribosomal protein S15 | -0.026012 |
| S100A10 | S100 calcium binding protein A10 | -0.0260014 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.025873 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0256701 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0249421 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0248913 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.024712 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0243649 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0243287 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.024285 |
| S100A11 | S100 calcium binding protein A11 | -0.024011 |
| MX2 | MX dynamin-like GTPase 2 | -0.0238977 |
| PTEN | phosphatase and tensin homolog | -0.023883 |
| RPS8 | ribosomal protein S8 | -0.0238532 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0238526 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0237726 |
| TMEM165 | transmembrane protein 165 | -0.0237433 |
| ATP11B | ATPase, class VI, type 11B | -0.0232923 |
| RTN4 | reticulon 4 | -0.0232208 |
