| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.116288 |
| FRMD6 | FERM domain containing 6 | 0.0889229 |
| SGMS2 | sphingomyelin synthase 2 | 0.0809605 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0567436 |
| INTS6 | integrator complex subunit 6 | 0.0520471 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0466008 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0464753 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0461779 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0461049 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0445347 |
| RCOR1 | REST corepressor 1 | 0.0405669 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0401913 |
| HMGA2 | high mobility group AT-hook 2 | 0.0361242 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0318913 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0310631 |
| PUM3 | pumilio RNA binding family member 3 | 0.0294775 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0289812 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0265047 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0253293 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.023807 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0237184 |
| ZNF800 | zinc finger protein 800 | 0.0233988 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0232762 |
| MCL1 | myeloid cell leukemia 1 | 0.0228615 |
| SATB2 | SATB homeobox 2 | 0.0228229 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0224372 |
| RPL23 | ribosomal protein L23 | 0.0218058 |
| H1-4 | H1.4 linker histone, cluster member | 0.0214602 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0212337 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0212242 |
| FLNA | filamin A, alpha | 0.0212234 |
| RPL3 | ribosomal protein L3 | 0.0207168 |
| AEBP2 | AE binding protein 2 | 0.0206966 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0198488 |
| PHF14 | PHD finger protein 14 | 0.0192422 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0190056 |
| CBFB | core-binding factor, beta subunit | 0.0189138 |
| SCFD2 | sec1 family domain containing 2 | 0.0187701 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0186698 |
| RPS4X | ribosomal protein S4, X-linked | 0.0186552 |
| HPCAL1 | hippocalcin-like 1 | 0.0184295 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0184002 |
| CTBP2 | C-terminal binding protein 2 | 0.0183666 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0182805 |
| AHNAK | AHNAK nucleoprotein | 0.0182213 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0178722 |
| TRIB1 | tribbles pseudokinase 1 | 0.017816 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.017792 |
| CPNE1 | copine I | 0.0175257 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0173697 |
| SON | SON DNA binding protein | 0.0171704 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0170561 |
| THADA | thyroid adenoma associated | 0.0169992 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0169063 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0167658 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0165334 |
| ACTN4 | actinin, alpha 4 | 0.0163597 |
| CORO1C | coronin, actin binding protein, 1C | 0.0163595 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0163584 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0163549 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0162554 |
| SRCAP | Snf2-related CREBBP activator protein | 0.0162232 |
| HDAC4 | histone deacetylase 4 | 0.016091 |
| NUDC | nudC nuclear distribution protein | 0.0159643 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0159212 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0158334 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0157854 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0157207 |
| CMIP | c-Maf inducing protein | 0.0156678 |
| RPSA | ribosomal protein SA | 0.0156536 |
| BRD2 | bromodomain containing 2 | 0.0156022 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0153726 |
| IER2 | immediate early response 2 | 0.0151058 |
| PRELID2 | PRELI domain containing 2 | 0.0150375 |
| RBM19 | RNA binding motif protein 19 | 0.0148732 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0147469 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0147041 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0146251 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0143785 |
| ANKAR | ankyrin and armadillo repeat containing | 0.0143644 |
| SKI | SKI proto-oncogene | 0.0143399 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0143313 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0142985 |
| MOSMO | modulator of smoothened | 0.0142877 |
| CORO2B | coronin, actin binding protein, 2B | 0.0142491 |
| STK24 | serine/threonine kinase 24 | 0.0140641 |
| MSH4 | mutS homolog 4 | 0.0140402 |
| PMM2 | phosphomannomutase 2 | 0.0139554 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.0138977 |
| ANKRD18A | ankyrin repeat domain 18A | 0.0138684 |
| DENND5A | DENN/MADD domain containing 5A | 0.0135775 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0134969 |
| AATF | apoptosis antagonizing transcription factor | 0.0134853 |
| TASP1 | taspase, threonine aspartase, 1 | 0.0134838 |
| KLF10 | Kruppel-like factor 10 | 0.0134223 |
| USP8 | ubiquitin specific peptidase 8 | 0.0134098 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0133898 |
| MX1 | MX dynamin-like GTPase 1 | 0.0133721 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0133592 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0132323 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | -0.176805 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.142655 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.110724 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.102084 |
| NAV3 | neuron navigator 3 | -0.101635 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0997965 |
| HDAC9 | histone deacetylase 9 | -0.0960651 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0873569 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.085612 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0829636 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0750604 |
| CALD1 | caldesmon 1 | -0.0737604 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0736245 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0654863 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0628216 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0604175 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0603314 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0591745 |
| TPM4 | tropomyosin 4 | -0.0588259 |
| JMJD1C | jumonji domain containing 1C | -0.0578144 |
| FRMD4A | FERM domain containing 4A | -0.0574739 |
| GOLGA4 | golgin A4 | -0.0569053 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0560639 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0545914 |
| PTK2 | protein tyrosine kinase 2 | -0.0528415 |
| RPS6 | ribosomal protein S6 | -0.0528133 |
| ZNF292 | zinc finger protein 292 | -0.0515581 |
| FLNB | filamin B, beta | -0.050882 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0498997 |
| NF1 | neurofibromin 1 | -0.0483412 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0483184 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0482671 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0475302 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0474595 |
| LAMB3 | laminin, beta 3 | -0.0461602 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0457259 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0452211 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0445898 |
| DGKI | diacylglycerol kinase, iota | -0.0439844 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0429316 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0428422 |
| CANX | calnexin | -0.04213 |
| BNC2 | basonuclin 2 | -0.0418218 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0410092 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0409705 |
| CALU | calumenin | -0.0399554 |
| GLG1 | golgi glycoprotein 1 | -0.0392323 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0390744 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0389678 |
| MTDH | metadherin | -0.038653 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0384983 |
| RASA2 | RAS p21 protein activator 2 | -0.0382514 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0378229 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0378194 |
| ANXA5 | annexin A5 | -0.03705 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0370398 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0368463 |
| TPD52 | tumor protein D52 | -0.0350682 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0348139 |
| TTR | transthyretin | -0.0345312 |
| TCF12 | transcription factor 12 | -0.0337056 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0336183 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0334947 |
| COG5 | component of oligomeric golgi complex 5 | -0.0334293 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0331657 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0331418 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0330888 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0330836 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0329109 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0324658 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0320151 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0319757 |
| RTN4 | reticulon 4 | -0.0316523 |
| CDK6 | cyclin-dependent kinase 6 | -0.0314771 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0314093 |
| SNX9 | sorting nexin 9 | -0.0313681 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0308857 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0308441 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0307666 |
| CRY1 | cryptochrome circadian clock 1 | -0.0307452 |
| ACTG1 | actin gamma 1 | -0.0303027 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0302787 |
| SEC24A | SEC24 family member A | -0.0292068 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.0291225 |
| RPS8 | ribosomal protein S8 | -0.0290331 |
| LMAN1 | lectin, mannose-binding, 1 | -0.028855 |
| BBX | bobby sox homolog (Drosophila) | -0.0286501 |
| SEC24D | SEC24 family member D | -0.0286493 |
| USP3 | ubiquitin specific peptidase 3 | -0.0286274 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0285655 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0285387 |
| ARFGEF3 | ARFGEF family member 3 | -0.0284747 |
| TRAM1 | translocation associated membrane protein 1 | -0.0284724 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0283552 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0281688 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0279566 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0278608 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0277217 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0277171 |
| PRKCE | protein kinase C, epsilon | -0.0273666 |
