| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0838826 |
| ASPH | aspartate beta-hydroxylase | 0.0648707 |
| AHNAK | AHNAK nucleoprotein | 0.0602308 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0565604 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0527338 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0496775 |
| SMAD3 | SMAD family member 3 | 0.0479462 |
| HMGA2 | high mobility group AT-hook 2 | 0.0478066 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0448638 |
| CAVIN1 | caveolae associated protein 1 | 0.0444373 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0420212 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0416226 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0413787 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0408109 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0407373 |
| HPCAL1 | hippocalcin-like 1 | 0.040243 |
| ANGPTL4 | angiopoietin-like 4 | 0.0390576 |
| PLEC | plectin | 0.037165 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0344724 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0339798 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0334086 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0328304 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0318487 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0313323 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0290797 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0286092 |
| OGA | O-GlcNAcase | 0.0280871 |
| CD44 | CD44 molecule (Indian blood group) | 0.0280508 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.027294 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0268624 |
| HDLBP | high density lipoprotein binding protein | 0.0266761 |
| STK10 | serine/threonine kinase 10 | 0.0263998 |
| RPL23 | ribosomal protein L23 | 0.0258653 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0257481 |
| H1-0 | H1.0 linker histone | 0.0248544 |
| FLNA | filamin A, alpha | 0.0248124 |
| SMYD3 | SET and MYND domain containing 3 | 0.0247806 |
| SVIL | supervillin | 0.0244973 |
| RASA3 | RAS p21 protein activator 3 | 0.0244215 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0243353 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0232926 |
| CEP250 | centrosomal protein 250kDa | 0.0232151 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0230607 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0230171 |
| SLC38A2 | solute carrier family 38, member 2 | 0.022909 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0227273 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0225267 |
| RRBP1 | ribosome binding protein 1 | 0.0225036 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0223957 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.022189 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0220794 |
| RPL4 | ribosomal protein L4 | 0.0220747 |
| MLPH | melanophilin | 0.0219549 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0218643 |
| RPL26 | ribosomal protein L26 | 0.0217668 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0217334 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0216843 |
| SETBP1 | SET binding protein 1 | 0.0213292 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.020899 |
| RPL14 | ribosomal protein L14 | 0.020806 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0207416 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0207104 |
| GOLGB1 | golgin B1 | 0.0206312 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0204879 |
| AFDN | afadin, adherens junction formation factor | 0.0203437 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0203046 |
| XAF1 | XIAP associated factor 1 | 0.0203019 |
| THBS1 | thrombospondin 1 | 0.0200882 |
| ZNF518A | zinc finger protein 518A | 0.0199918 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0198081 |
| TMEM132D | transmembrane protein 132D | 0.0196098 |
| FAT1 | FAT atypical cadherin 1 | 0.0195143 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0191716 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0190747 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0190728 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0190042 |
| RASA2 | RAS p21 protein activator 2 | 0.018979 |
| ATM | ATM serine/threonine kinase | 0.018869 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0186548 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0185148 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0184774 |
| AEBP2 | AE binding protein 2 | 0.0184251 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0182201 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0180112 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.017942 |
| KIAA1328 | KIAA1328 | 0.0179409 |
| SP100 | SP100 nuclear antigen | 0.0178151 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0178016 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.017594 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0175014 |
| EXT1 | exostosin glycosyltransferase 1 | 0.017475 |
| SEPTIN9 | septin 9 | 0.0172537 |
| KLF10 | Kruppel-like factor 10 | 0.0169965 |
| PHF3 | PHD finger protein 3 | 0.0169378 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0166838 |
| RPL3 | ribosomal protein L3 | 0.0166316 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.016597 |
| CAB39 | calcium binding protein 39 | 0.0164749 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.016338 |
| CORO1C | coronin, actin binding protein, 1C | 0.0162415 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.228758 |
| VIM | vimentin | -0.203044 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.179977 |
| NDRG1 | N-myc downstream regulated 1 | -0.159243 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138783 |
| POTEF | POTE ankyrin domain family, member F | -0.13499 |
| FTL | ferritin, light polypeptide | -0.109018 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0976464 |
| HLA-B | major histocompatibility complex, class I, B | -0.0969304 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0839952 |
| COL1A1 | collagen, type I, alpha 1 | -0.0836147 |
| NRP1 | neuropilin 1 | -0.0832453 |
| B2M | beta-2-microglobulin | -0.0801901 |
| CDH13 | cadherin 13 | -0.0760184 |
| TPM1 | tropomyosin 1 (alpha) | -0.0731469 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0730272 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0727534 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0632932 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0625787 |
| TMSB10 | thymosin beta 10 | -0.0608541 |
| COL1A2 | collagen, type I, alpha 2 | -0.0582349 |
| CADM1 | cell adhesion molecule 1 | -0.0580569 |
| MMP12 | matrix metallopeptidase 12 | -0.0570244 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0562375 |
| MEF2A | myocyte enhancer factor 2A | -0.0561325 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0521403 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0513861 |
| ITGA11 | integrin, alpha 11 | -0.0511552 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.050947 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0481442 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0474953 |
| VEGFA | vascular endothelial growth factor A | -0.0468292 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0464689 |
| TNS3 | tensin 3 | -0.0459021 |
| PKM | pyruvate kinase, muscle | -0.0455731 |
| S100A6 | S100 calcium binding protein A6 | -0.0452737 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0441742 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0432202 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0431803 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0421289 |
| DSTN | destrin (actin depolymerizing factor) | -0.0415334 |
| GOLGA4 | golgin A4 | -0.0414736 |
| IL1B | interleukin 1, beta | -0.0403791 |
| EGR1 | early growth response 1 | -0.0400188 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0397471 |
| NAV1 | neuron navigator 1 | -0.0393837 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0383052 |
| FOSL1 | FOS-like antigen 1 | -0.0380571 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0379942 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0378887 |
| CDCP1 | CUB domain containing protein 1 | -0.0378712 |
| TPM4 | tropomyosin 4 | -0.0376342 |
| NBAS | neuroblastoma amplified sequence | -0.0368851 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0359533 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0358735 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0355983 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0353223 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0350015 |
| HLA-A | major histocompatibility complex, class I, A | -0.0337844 |
| MMP2 | matrix metallopeptidase 2 | -0.0336331 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0336012 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0334132 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0325639 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0324526 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0323278 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0318177 |
| BSG | basigin (Ok blood group) | -0.0313948 |
| TAPBP | TAP binding protein (tapasin) | -0.0313261 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0307534 |
| MSR1 | macrophage scavenger receptor 1 | -0.0307174 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0306947 |
| TMEM165 | transmembrane protein 165 | -0.030547 |
| PTK2 | protein tyrosine kinase 2 | -0.0301969 |
| ARF4 | ADP-ribosylation factor 4 | -0.0301445 |
| UBC | ubiquitin C | -0.0301163 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0298876 |
| TAGLN2 | transgelin 2 | -0.0296336 |
| LOXL2 | lysyl oxidase-like 2 | -0.0293675 |
| TGM2 | transglutaminase 2 | -0.0291594 |
| STC1 | stanniocalcin 1 | -0.0290318 |
| MTSS1 | metastasis suppressor 1 | -0.0290249 |
| PFN1 | profilin 1 | -0.0289168 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0285669 |
| MX2 | MX dynamin-like GTPase 2 | -0.0283988 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0282372 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0280113 |
| SNX9 | sorting nexin 9 | -0.0275461 |
| INHBA | inhibin, beta A | -0.0274848 |
| RND3 | Rho family GTPase 3 | -0.0273891 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.026704 |
| CA12 | carbonic anhydrase XII | -0.026539 |
| LDHA | lactate dehydrogenase A | -0.0262619 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0261307 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0260062 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0257773 |
| GLIS3 | GLIS family zinc finger 3 | -0.0257175 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.0251936 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0250578 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0250553 |
| C1R | complement component 1, r subcomponent | -0.0250456 |
