| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.155031 |
| FNDC3B | fibronectin type III domain containing 3B | 0.147164 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0774039 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0755481 |
| PLEC | plectin | 0.0750424 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0711549 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0696263 |
| FRMD4A | FERM domain containing 4A | 0.0666128 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0660445 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0655121 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0638446 |
| MSN | moesin | 0.0634751 |
| DST | dystonin | 0.0618085 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0565911 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0561215 |
| FMNL2 | formin-like 2 | 0.0523854 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0520611 |
| RUNX1 | runt-related transcription factor 1 | 0.0497363 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0478834 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0462119 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0422994 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0421817 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0416698 |
| RNF145 | ring finger protein 145 | 0.0409894 |
| ACTN1 | actinin, alpha 1 | 0.0408421 |
| AMOTL1 | angiomotin like 1 | 0.0407626 |
| FLNA | filamin A, alpha | 0.0404936 |
| AFDN | afadin, adherens junction formation factor | 0.0400051 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0367879 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0361742 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0361298 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0359529 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0358531 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0356777 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0354529 |
| HDAC9 | histone deacetylase 9 | 0.0350965 |
| FRMD5 | FERM domain containing 5 | 0.0350574 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0348754 |
| NAV2 | neuron navigator 2 | 0.0346886 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0338997 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0330808 |
| EP300 | E1A binding protein p300 | 0.0327112 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0324867 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0320806 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0320289 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0320105 |
| FN1 | fibronectin 1 | 0.031646 |
| RPL3 | ribosomal protein L3 | 0.0314372 |
| QKI | QKI, KH domain containing, RNA binding | 0.0313522 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0313181 |
| SPAG9 | sperm associated antigen 9 | 0.0311257 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0308851 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0307013 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0306615 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0306224 |
| CENPF | centromere protein F, 350/400kDa | 0.0304056 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0303192 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0298527 |
| CDK6 | cyclin-dependent kinase 6 | 0.0295974 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0293363 |
| ANLN | anillin, actin binding protein | 0.0292261 |
| TPM3 | tropomyosin 3 | 0.0292076 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0291161 |
| ATP13A3 | ATPase type 13A3 | 0.0288644 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0288571 |
| SFPQ | splicing factor proline/glutamine-rich | 0.028841 |
| ACTN4 | actinin, alpha 4 | 0.0288049 |
| AHNAK | AHNAK nucleoprotein | 0.0284007 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0281996 |
| OGA | O-GlcNAcase | 0.0281798 |
| MELTF | melanotransferrin | 0.0280475 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0280272 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0277973 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0275626 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.027509 |
| RNF213 | ring finger protein 213 | 0.0271552 |
| ATXN1 | ataxin 1 | 0.0270817 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.026918 |
| CORO1C | coronin, actin binding protein, 1C | 0.0264584 |
| ETV6 | ets variant 6 | 0.026293 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0259446 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0259132 |
| CTTN | cortactin | 0.0254006 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0253031 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0248487 |
| OPHN1 | oligophrenin 1 | 0.0246033 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0245481 |
| MCL1 | myeloid cell leukemia 1 | 0.0243647 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.024124 |
| HELZ | helicase with zinc finger | 0.0241117 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0240672 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0239805 |
| OXSR1 | oxidative stress responsive 1 | 0.0237287 |
| KYNU | kynureninase | 0.0236205 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0234877 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0233959 |
| SMAD3 | SMAD family member 3 | 0.0232736 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0232666 |
| HMG20B | high mobility group 20B | 0.0232259 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0229662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.30416 |
| NLGN1 | neuroligin 1 | -0.167875 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.156846 |
| MT2A | metallothionein 2A | -0.121541 |
| LSAMP | limbic system-associated membrane protein | -0.0998886 |
| RPL35A | ribosomal protein L35a | -0.0855499 |
| RPLP1 | ribosomal protein, large, P1 | -0.0840076 |
| TMSB10 | thymosin beta 10 | -0.0781641 |
| RPS6 | ribosomal protein S6 | -0.0704353 |
| FTL | ferritin, light polypeptide | -0.0699164 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0688872 |
| NRG3 | neuregulin 3 | -0.062358 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0562199 |
| PTMA | prothymosin, alpha | -0.0527348 |
| RPS8 | ribosomal protein S8 | -0.0512488 |
| RPS13 | ribosomal protein S13 | -0.0510844 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0491602 |
| SQSTM1 | sequestosome 1 | -0.0485072 |
| RPS3 | ribosomal protein S3 | -0.0472925 |
| RPLP2 | ribosomal protein, large, P2 | -0.0465151 |
| RPL37A | ribosomal protein L37a | -0.045667 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0437921 |
| NDRG1 | N-myc downstream regulated 1 | -0.0433651 |
| RPS12 | ribosomal protein S12 | -0.0408686 |
| RPL31 | ribosomal protein L31 | -0.0408358 |
| FHIT | fragile histidine triad | -0.0407157 |
| RACK1 | receptor for activated C kinase 1 | -0.0406525 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0404435 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0395831 |
| RPS21 | ribosomal protein S21 | -0.0392646 |
| RPL12 | ribosomal protein L12 | -0.0392126 |
| HLA-B | major histocompatibility complex, class I, B | -0.039201 |
| RPL34 | ribosomal protein L34 | -0.0387022 |
| RPS29 | ribosomal protein S29 | -0.0384024 |
| ENO1 | enolase 1, (alpha) | -0.0373029 |
| RPS24 | ribosomal protein S24 | -0.0369677 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0366112 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0365359 |
| RPL9 | ribosomal protein L9 | -0.0364296 |
| RPL5 | ribosomal protein L5 | -0.0357415 |
| RPL38 | ribosomal protein L38 | -0.0355052 |
| PRAME | preferentially expressed antigen in melanoma | -0.0353245 |
| RPS23 | ribosomal protein S23 | -0.0350527 |
| RPS14 | ribosomal protein S14 | -0.0341946 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0341267 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0339829 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0339275 |
| GOLGA4 | golgin A4 | -0.0331585 |
| CADM1 | cell adhesion molecule 1 | -0.0323605 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0322961 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0317414 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0311376 |
| HMGA1 | high mobility group AT-hook 1 | -0.0305023 |
| RPL37 | ribosomal protein L37 | -0.0303527 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0301963 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0297224 |
| TBCA | tubulin folding cofactor A | -0.0294819 |
| RPL36A | ribosomal protein L36a | -0.029279 |
| S100A9 | S100 calcium binding protein A9 | -0.0292766 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.028958 |
| RPL23 | ribosomal protein L23 | -0.0289412 |
| RPL11 | ribosomal protein L11 | -0.0282572 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0280166 |
| RPS16 | ribosomal protein S16 | -0.0277204 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0276333 |
| RPS27A | ribosomal protein S27a | -0.0271717 |
| RPL32 | ribosomal protein L32 | -0.0270766 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F | -0.0269827 |
| RPL30 | ribosomal protein L30 | -0.0269719 |
| RPL28 | ribosomal protein L28 | -0.0267517 |
| CTSD | cathepsin D | -0.0260428 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0258025 |
| RPL36 | ribosomal protein L36 | -0.0257562 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.0257214 |
| TOB2 | transducer of ERBB2, 2 | -0.0255311 |
| ACTG1 | actin gamma 1 | -0.025477 |
| CDH13 | cadherin 13 | -0.024941 |
| RPL27 | ribosomal protein L27 | -0.02489 |
| APOD | apolipoprotein D | -0.0246198 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0243333 |
| RPL26 | ribosomal protein L26 | -0.0242969 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0242241 |
| RPL19 | ribosomal protein L19 | -0.0241333 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0240928 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0237913 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0235319 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0233123 |
| RPL13A | ribosomal protein L13a | -0.0232571 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0231098 |
| RPS19 | ribosomal protein S19 | -0.0223288 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0219322 |
| HSPB1 | heat shock 27kDa protein 1 | -0.021756 |
| RPS15 | ribosomal protein S15 | -0.0215983 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0215831 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0214626 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0214087 |
| RPL27A | ribosomal protein L27a | -0.0211791 |
| ENTHD1 | ENTH domain containing 1 | -0.0209437 |
| MT1X | metallothionein 1X | -0.020882 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0208379 |
