| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0913406 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0765488 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0671073 |
| PKM | pyruvate kinase, muscle | 0.0543912 |
| TMSB4X | thymosin beta 4, X-linked | 0.0518624 |
| PRELID2 | PRELI domain containing 2 | 0.0463309 |
| PDGFC | platelet derived growth factor C | 0.0452201 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0432071 |
| TRERF1 | transcriptional regulating factor 1 | 0.0400923 |
| ZNF608 | zinc finger protein 608 | 0.0380182 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0367999 |
| RPL3 | ribosomal protein L3 | 0.0334335 |
| AHNAK | AHNAK nucleoprotein | 0.0328474 |
| XPO1 | exportin 1 | 0.0318673 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0311928 |
| NCKAP1 | NCK-associated protein 1 | 0.0303781 |
| MACROD2 | MACRO domain containing 2 | 0.0302253 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0290539 |
| PYGB | phosphorylase, glycogen; brain | 0.028426 |
| SMYD3 | SET and MYND domain containing 3 | 0.0281784 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0276763 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0275284 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0274748 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0273641 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0263202 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0263161 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0260676 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0257718 |
| H1-4 | H1.4 linker histone, cluster member | 0.0257565 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0251233 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0239444 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0237767 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0237052 |
| TJP1 | tight junction protein 1 | 0.023009 |
| EGFR | epidermal growth factor receptor | 0.0228668 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.022209 |
| NBAS | neuroblastoma amplified sequence | 0.0220119 |
| GSE1 | Gse1 coiled-coil protein | 0.0219609 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0216741 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0212849 |
| PCM1 | pericentriolar material 1 | 0.0211197 |
| RNF145 | ring finger protein 145 | 0.02104 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0208012 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0206994 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.020647 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0205682 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0203944 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0201147 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0200745 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0199259 |
| KLC1 | kinesin light chain 1 | 0.0197041 |
| YEATS2 | YEATS domain containing 2 | 0.0192547 |
| AMOTL2 | angiomotin like 2 | 0.019162 |
| TRIM24 | tripartite motif containing 24 | 0.0190094 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0189408 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0189236 |
| CCNL1 | cyclin L1 | 0.0188197 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0185109 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.018503 |
| SETD5 | SET domain containing 5 | 0.0181579 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0178068 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0177366 |
| CEP250 | centrosomal protein 250kDa | 0.0174659 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0173833 |
| PLEC | plectin | 0.0173638 |
| TMEM65 | transmembrane protein 65 | 0.0172913 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0172815 |
| TBC1D5 | TBC1 domain family, member 5 | 0.017223 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0171127 |
| PRRC2C | proline-rich coiled-coil 2C | 0.017067 |
| SMAD6 | SMAD family member 6 | 0.0170057 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0168273 |
| PGK1 | phosphoglycerate kinase 1 | 0.016799 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0166824 |
| YAP1 | Yes-associated protein 1 | 0.0166329 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0163746 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0163681 |
| CPNE1 | copine I | 0.0163225 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0162885 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0161494 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0160191 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0158678 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0157831 |
| TPR | translocated promoter region, nuclear basket protein | 0.0157087 |
| TXNRD1 | thioredoxin reductase 1 | 0.0156724 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0156304 |
| DST | dystonin | 0.015619 |
| TXNIP | thioredoxin interacting protein | 0.0156019 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0155804 |
| YTHDC1 | YTH domain containing 1 | 0.0155487 |
| RBM33 | RNA binding motif protein 33 | 0.0154952 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0154151 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0152185 |
| EP300 | E1A binding protein p300 | 0.0151983 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0151245 |
| ABHD12 | abhydrolase domain containing 12 | 0.0150557 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0150204 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0149832 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0148733 |
| USP34 | ubiquitin specific peptidase 34 | 0.0147858 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.238549 |
| PTMA | prothymosin, alpha | -0.235392 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.199605 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.160505 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.156949 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.155306 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.109267 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0907474 |
| BMP10 | bone morphogenetic protein 10 | -0.0860549 |
| RPS6 | ribosomal protein S6 | -0.0789415 |
| CCND1 | cyclin D1 | -0.066013 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0609861 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0588922 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0549431 |
| RPL35A | ribosomal protein L35a | -0.0545447 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0531949 |
| RPS8 | ribosomal protein S8 | -0.0504865 |
| ACTG1 | actin gamma 1 | -0.0401803 |
| EVI5 | ecotropic viral integration site 5 | -0.0379802 |
| MKI67 | marker of proliferation Ki-67 | -0.0374098 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0367411 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0362991 |
| RPL19 | ribosomal protein L19 | -0.0359494 |
| RPLP1 | ribosomal protein, large, P1 | -0.035838 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0344926 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0338127 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0320521 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0315485 |
| NEBL | nebulette | -0.0310124 |
| RPS23 | ribosomal protein S23 | -0.0309061 |
| RPL34 | ribosomal protein L34 | -0.0301542 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0301384 |
| RPS13 | ribosomal protein S13 | -0.0301372 |
| LDHA | lactate dehydrogenase A | -0.0299547 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0298504 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0298087 |
| ZNF438 | zinc finger protein 438 | -0.0297815 |
| DIAPH3 | diaphanous-related formin 3 | -0.0296712 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0295944 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0290139 |
| RPL9 | ribosomal protein L9 | -0.0290137 |
| VCL | vinculin | -0.028592 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0284365 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.028165 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.027933 |
| RPL31 | ribosomal protein L31 | -0.0277628 |
| RPL11 | ribosomal protein L11 | -0.0275969 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0272216 |
| TPM4 | tropomyosin 4 | -0.0272118 |
| POTEF | POTE ankyrin domain family, member F | -0.0268203 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0264255 |
| PDE7B | phosphodiesterase 7B | -0.0263935 |
| CENPF | centromere protein F, 350/400kDa | -0.0263841 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0256921 |
| S100A6 | S100 calcium binding protein A6 | -0.0256108 |
| EFNA5 | ephrin-A5 | -0.025453 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0254392 |
| RPS25 | ribosomal protein S25 | -0.0250716 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0249952 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0239347 |
| RACK1 | receptor for activated C kinase 1 | -0.0237781 |
| TUBA1B | tubulin, alpha 1b | -0.0237158 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0235974 |
| FOXP1 | forkhead box P1 | -0.0234439 |
| NBEA | neurobeachin | -0.0230985 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0229213 |
| RPL36 | ribosomal protein L36 | -0.0228006 |
| RPL26 | ribosomal protein L26 | -0.0227265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.02258 |
| S100A4 | S100 calcium binding protein A4 | -0.0225559 |
| GPHN | gephyrin | -0.022464 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0223905 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0223524 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0222721 |
| HJURP | Holliday junction recognition protein | -0.0221285 |
| RPL32 | ribosomal protein L32 | -0.0218862 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0216415 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0214532 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0213781 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0212435 |
| RPL8 | ribosomal protein L8 | -0.0210469 |
| CUX1 | cut-like homeobox 1 | -0.0210427 |
| RPLP0 | ribosomal protein, large, P0 | -0.0208931 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0208385 |
| RPL37A | ribosomal protein L37a | -0.0208111 |
| RPL30 | ribosomal protein L30 | -0.0207314 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0205448 |
| RPS27A | ribosomal protein S27a | -0.0204241 |
| ENO1 | enolase 1, (alpha) | -0.0201759 |
| EMP3 | epithelial membrane protein 3 | -0.0198508 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0197906 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0196399 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0195557 |
| S100A9 | S100 calcium binding protein A9 | -0.0193002 |
| TBCA | tubulin folding cofactor A | -0.0192133 |
| RPL37 | ribosomal protein L37 | -0.0191944 |
| TUBB | tubulin, beta class I | -0.0191571 |
| RPL5 | ribosomal protein L5 | -0.019055 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0189804 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0189597 |
