| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.269355 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.15905 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0855426 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0825762 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0782436 |
| ADM | adrenomedullin | 0.0754511 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0727862 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0660606 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0656206 |
| IER3 | immediate early response 3 | 0.0649049 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0610086 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0608164 |
| FTL | ferritin, light polypeptide | 0.0603573 |
| COL5A1 | collagen, type V, alpha 1 | 0.0596454 |
| ASPH | aspartate beta-hydroxylase | 0.0575026 |
| CDH13 | cadherin 13 | 0.0572008 |
| CALR | calreticulin | 0.0566658 |
| INTS6 | integrator complex subunit 6 | 0.0551751 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0545438 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0515125 |
| MT2A | metallothionein 2A | 0.0510826 |
| TMSB10 | thymosin beta 10 | 0.0507116 |
| B2M | beta-2-microglobulin | 0.0503066 |
| RPL23 | ribosomal protein L23 | 0.0501811 |
| HDAC9 | histone deacetylase 9 | 0.0500236 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0485787 |
| RPS12 | ribosomal protein S12 | 0.0476317 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0474324 |
| RPS3 | ribosomal protein S3 | 0.0456365 |
| VIM | vimentin | 0.0450975 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.042714 |
| PTMA | prothymosin, alpha | 0.0419471 |
| FMNL2 | formin-like 2 | 0.0412859 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0410287 |
| TMSB4X | thymosin beta 4, X-linked | 0.0405096 |
| ENO1 | enolase 1, (alpha) | 0.0400765 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0398492 |
| SQSTM1 | sequestosome 1 | 0.0391081 |
| RPL37A | ribosomal protein L37a | 0.0388824 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0376933 |
| RPL7A | ribosomal protein L7a | 0.0368985 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.036284 |
| TMEM132D | transmembrane protein 132D | 0.0356913 |
| RPS8 | ribosomal protein S8 | 0.0350939 |
| SEPTIN9 | septin 9 | 0.0349961 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0347026 |
| HMGA2 | high mobility group AT-hook 2 | 0.0345382 |
| MSN | moesin | 0.0340253 |
| MLPH | melanophilin | 0.0339833 |
| CEP250 | centrosomal protein 250kDa | 0.0331834 |
| RND3 | Rho family GTPase 3 | 0.0326037 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0323816 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.032178 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0319828 |
| RPS6 | ribosomal protein S6 | 0.0316631 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0312063 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0308619 |
| PRELID2 | PRELI domain containing 2 | 0.0296697 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0294792 |
| AHNAK | AHNAK nucleoprotein | 0.0291853 |
| RPL12 | ribosomal protein L12 | 0.0283338 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0281594 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0279037 |
| COL7A1 | collagen, type VII, alpha 1 | 0.027814 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0267384 |
| CANX | calnexin | 0.0265409 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0261856 |
| BRD2 | bromodomain containing 2 | 0.0259532 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258673 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0258201 |
| MYO10 | myosin X | 0.0257819 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0257201 |
| RPL3 | ribosomal protein L3 | 0.0256477 |
| EGFR | epidermal growth factor receptor | 0.0255301 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0254931 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0254716 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0252697 |
| DST | dystonin | 0.0251305 |
| COL6A2 | collagen, type VI, alpha 2 | 0.024975 |
| RPLP2 | ribosomal protein, large, P2 | 0.0248797 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0247166 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.02471 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0244777 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0243588 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0242239 |
| GPC6 | glypican 6 | 0.0242221 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.024194 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0239372 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0238239 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0235059 |
| PGK1 | phosphoglycerate kinase 1 | 0.0234528 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0234454 |
| TPI1 | triosephosphate isomerase 1 | 0.0233618 |
| SMYD3 | SET and MYND domain containing 3 | 0.0230338 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.022982 |
| DUSP10 | dual specificity phosphatase 10 | 0.0228409 |
| RPS19 | ribosomal protein S19 | 0.0226798 |
| GOLGB1 | golgin B1 | 0.022403 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0222281 |
| JUN | jun proto-oncogene | 0.0218975 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.215058 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.16551 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.146133 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.106468 |
| CD44 | CD44 molecule (Indian blood group) | -0.0931744 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0831265 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0817987 |
| VCL | vinculin | -0.0775026 |
| BICC1 | BicC family RNA binding protein 1 | -0.0745314 |
| RTN4 | reticulon 4 | -0.0731343 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0721627 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0638906 |
| MKI67 | marker of proliferation Ki-67 | -0.0591802 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0589139 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0584053 |
| CDCP1 | CUB domain containing protein 1 | -0.0572729 |
| TPM4 | tropomyosin 4 | -0.0562962 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0547584 |
| CENPF | centromere protein F, 350/400kDa | -0.0547263 |
| OSMR | oncostatin M receptor | -0.0539176 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0527031 |
| FRMD4A | FERM domain containing 4A | -0.0520752 |
| TAPBP | TAP binding protein (tapasin) | -0.0497418 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0480358 |
| SBF2 | SET binding factor 2 | -0.0478861 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0470045 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0445595 |
| SMAD3 | SMAD family member 3 | -0.0444839 |
| RIGI | RNA sensor RIG-I | -0.0432779 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0430571 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0428228 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0413147 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0412405 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0412346 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0403004 |
| MX1 | MX dynamin-like GTPase 1 | -0.040222 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0393938 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0392075 |
| TXNRD1 | thioredoxin reductase 1 | -0.038478 |
| PALLD | palladin, cytoskeletal associated protein | -0.0377655 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0375624 |
| THBS1 | thrombospondin 1 | -0.0371063 |
| ANXA2 | annexin A2 | -0.0370375 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0364699 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0355669 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0354682 |
| FRMD5 | FERM domain containing 5 | -0.0351724 |
| NDRG1 | N-myc downstream regulated 1 | -0.0340568 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.03373 |
| KIF4A | kinesin family member 4A | -0.0332968 |
| PLSCR1 | phospholipid scramblase 1 | -0.0332226 |
| HLA-E | major histocompatibility complex, class I, E | -0.0329423 |
| NCOA7 | nuclear receptor coactivator 7 | -0.03206 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0320419 |
| TPX2 | TPX2, microtubule-associated | -0.0311429 |
| DIAPH3 | diaphanous-related formin 3 | -0.0304383 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0301315 |
| RNF24 | ring finger protein 24 | -0.0299634 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0298822 |
| EGR1 | early growth response 1 | -0.0296984 |
| JMJD1C | jumonji domain containing 1C | -0.0294707 |
| RASA2 | RAS p21 protein activator 2 | -0.0293918 |
| KLF6 | Kruppel-like factor 6 | -0.0287762 |
| DENND5A | DENN/MADD domain containing 5A | -0.0286499 |
| CADM1 | cell adhesion molecule 1 | -0.0286091 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0284963 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0282018 |
| VMP1 | vacuole membrane protein 1 | -0.0280713 |
| ANLN | anillin, actin binding protein | -0.0279221 |
| TNNC1 | troponin C type 1 (slow) | -0.0278709 |
| SYAP1 | synapse associated protein 1 | -0.0277157 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0276935 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0275841 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0268078 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0266588 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0266441 |
| RAI14 | retinoic acid induced 14 | -0.0266278 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0262846 |
| ARRDC3 | arrestin domain containing 3 | -0.0262671 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0261247 |
| MX2 | MX dynamin-like GTPase 2 | -0.0258534 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0253198 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.025221 |
| LOXL2 | lysyl oxidase-like 2 | -0.0251764 |
| RUNX2 | runt-related transcription factor 2 | -0.0250547 |
| THOC2 | THO complex 2 | -0.0249677 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0246592 |
| CTSD | cathepsin D | -0.0245241 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0244407 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.024315 |
| TMEM41B | transmembrane protein 41B | -0.0242686 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0239967 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0239471 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0236194 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0234344 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0233355 |
| NF1 | neurofibromin 1 | -0.0232809 |
| DUSP5 | dual specificity phosphatase 5 | -0.0227292 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0226622 |
| KIF18A | kinesin family member 18A | -0.0226437 |
