| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.248158 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.218063 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0745621 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0599308 |
| AHNAK | AHNAK nucleoprotein | 0.0583056 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0571164 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0565083 |
| SMAD3 | SMAD family member 3 | 0.0538116 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0516473 |
| ARRDC3 | arrestin domain containing 3 | 0.0492068 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0462583 |
| KYNU | kynureninase | 0.0461133 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0451045 |
| CD44 | CD44 molecule (Indian blood group) | 0.0437929 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0425628 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0376998 |
| FAM13A | family with sequence similarity 13, member A | 0.0376917 |
| FAT1 | FAT atypical cadherin 1 | 0.0363945 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0362471 |
| PLEC | plectin | 0.0353004 |
| MSN | moesin | 0.0351192 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0332888 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0327267 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0323542 |
| ATP13A3 | ATPase type 13A3 | 0.0308364 |
| FLNA | filamin A, alpha | 0.030768 |
| MED13L | mediator complex subunit 13-like | 0.0302152 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0295918 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.029467 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0288851 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0286632 |
| WDR26 | WD repeat domain 26 | 0.0286382 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0283921 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0282921 |
| ASPH | aspartate beta-hydroxylase | 0.0282764 |
| HPCAL1 | hippocalcin-like 1 | 0.0275741 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0270279 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0270002 |
| ADM | adrenomedullin | 0.026712 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0265345 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0261645 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0254104 |
| APP | amyloid beta (A4) precursor protein | 0.0244738 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0240413 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0237132 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0235203 |
| RNF24 | ring finger protein 24 | 0.0234318 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0234182 |
| GSE1 | Gse1 coiled-coil protein | 0.0232585 |
| ANO6 | anoctamin 6 | 0.023227 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0229312 |
| ACTN1 | actinin, alpha 1 | 0.0228703 |
| SMYD3 | SET and MYND domain containing 3 | 0.0228256 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0227831 |
| TXNIP | thioredoxin interacting protein | 0.0227654 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0226579 |
| CENPF | centromere protein F, 350/400kDa | 0.0225249 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0221314 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0219458 |
| CFDP1 | craniofacial development protein 1 | 0.0216752 |
| IL1R1 | interleukin 1 receptor, type I | 0.0215192 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0212545 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0212267 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0208846 |
| MYO10 | myosin X | 0.0207544 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0204152 |
| AHR | aryl hydrocarbon receptor | 0.0203778 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0203663 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0203409 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0202461 |
| HDAC9 | histone deacetylase 9 | 0.0201393 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0200592 |
| TXNRD1 | thioredoxin reductase 1 | 0.019951 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0199195 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0198739 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0198064 |
| EP300 | E1A binding protein p300 | 0.0196313 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0195695 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0195633 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0195625 |
| TLN1 | talin 1 | 0.019523 |
| CAB39 | calcium binding protein 39 | 0.0193285 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0193196 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0193116 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0192622 |
| MEF2A | myocyte enhancer factor 2A | 0.0191363 |
| NONO | non-POU domain containing, octamer-binding | 0.0190939 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0187692 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0187682 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0186761 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0184795 |
| DST | dystonin | 0.0184468 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0183738 |
| RLF | rearranged L-myc fusion | 0.0183712 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0182815 |
| JAG1 | jagged 1 | 0.018241 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0181524 |
| ATXN1 | ataxin 1 | 0.0180692 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0180393 |
| EXOC6B | exocyst complex component 6B | 0.0176734 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.214616 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166324 |
| HLA-B | major histocompatibility complex, class I, B | -0.15633 |
| VIM | vimentin | -0.13437 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.126664 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.110253 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.10678 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.102275 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0994829 |
| TMSB10 | thymosin beta 10 | -0.0845651 |
| CDH13 | cadherin 13 | -0.0810344 |
| POTEF | POTE ankyrin domain family, member F | -0.0807194 |
| IL6 | interleukin 6 | -0.0760612 |
| FN1 | fibronectin 1 | -0.0728542 |
| FTL | ferritin, light polypeptide | -0.0678892 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0669109 |
| HLA-C | major histocompatibility complex, class I, C | -0.0662335 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0645559 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0559667 |
| PTMA | prothymosin, alpha | -0.0551902 |
| HLA-A | major histocompatibility complex, class I, A | -0.0543932 |
| LOX | lysyl oxidase | -0.0532761 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0504745 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0504665 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0490121 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0486268 |
| COL6A1 | collagen, type VI, alpha 1 | -0.045621 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0435608 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0424152 |
| EGFR | epidermal growth factor receptor | -0.0414367 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0409322 |
| S100A6 | S100 calcium binding protein A6 | -0.0404165 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0396984 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0393914 |
| RAI14 | retinoic acid induced 14 | -0.0384923 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0370267 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0369456 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.036547 |
| TMEM165 | transmembrane protein 165 | -0.0362679 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0354949 |
| FNIP1 | folliculin interacting protein 1 | -0.0351238 |
| UBC | ubiquitin C | -0.0347384 |
| HM13 | histocompatibility (minor) 13 | -0.0340207 |
| NDRG1 | N-myc downstream regulated 1 | -0.0335311 |
| MAP4 | microtubule-associated protein 4 | -0.031981 |
| COL1A2 | collagen, type I, alpha 2 | -0.0314161 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.031334 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.031094 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.031038 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0305654 |
| S100A10 | S100 calcium binding protein A10 | -0.030473 |
| HMGA2 | high mobility group AT-hook 2 | -0.030282 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0300761 |
| TPM4 | tropomyosin 4 | -0.030051 |
| RPL11 | ribosomal protein L11 | -0.0288879 |
| PTGES2 | prostaglandin E synthase 2 | -0.0288666 |
| MMP12 | matrix metallopeptidase 12 | -0.0288549 |
| COG6 | component of oligomeric golgi complex 6 | -0.0280627 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0278936 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0277036 |
| MORF4L2 | mortality factor 4 like 2 | -0.0271359 |
| TPM1 | tropomyosin 1 (alpha) | -0.0269936 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0267963 |
| TNS3 | tensin 3 | -0.0265533 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0264462 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0264224 |
| COL5A1 | collagen, type V, alpha 1 | -0.0264184 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0264093 |
| RPS6 | ribosomal protein S6 | -0.0255717 |
| ACTG1 | actin gamma 1 | -0.0255423 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0254176 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0251168 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0250956 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0249117 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0248465 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0248041 |
| NBAS | neuroblastoma amplified sequence | -0.0247708 |
| B2M | beta-2-microglobulin | -0.0245216 |
| TUBA1B | tubulin, alpha 1b | -0.0239396 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0234072 |
| S100A9 | S100 calcium binding protein A9 | -0.0233064 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.023247 |
| RAB6A | RAB6A, member RAS oncogene family | -0.023015 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0228952 |
| BSG | basigin (Ok blood group) | -0.0228279 |
| RPL31 | ribosomal protein L31 | -0.0223928 |
| LSAMP | limbic system-associated membrane protein | -0.0222944 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.0222617 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0221823 |
| NUCB2 | nucleobindin 2 | -0.0220942 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0219334 |
| NOP58 | NOP58 ribonucleoprotein | -0.0218318 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.02174 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0214407 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0214283 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0211501 |
| TTYH3 | tweety family member 3 | -0.0210683 |
| COL5A2 | collagen, type V, alpha 2 | -0.0210362 |
| MAGT1 | magnesium transporter 1 | -0.0209898 |
| CCNI | cyclin I | -0.0209317 |
