| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0701049 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0687883 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0521566 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0520449 |
| FMNL2 | formin-like 2 | 0.0498547 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0469497 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0464399 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0432567 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0416316 |
| RTN4 | reticulon 4 | 0.0398647 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0395989 |
| SMAD3 | SMAD family member 3 | 0.0393103 |
| RIGI | RNA sensor RIG-I | 0.0390282 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0390006 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0367541 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0366442 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0354031 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0353076 |
| FLNA | filamin A, alpha | 0.0343924 |
| ETNK1 | ethanolamine kinase 1 | 0.0338309 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.033763 |
| PRR16 | proline rich 16 | 0.0334021 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0332649 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0330965 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0329271 |
| RNF145 | ring finger protein 145 | 0.0328562 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0319708 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.03196 |
| SET | SET nuclear proto-oncogene | 0.0316217 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0301232 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0295142 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0292504 |
| GPC6 | glypican 6 | 0.0287404 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0282872 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.028224 |
| AHNAK | AHNAK nucleoprotein | 0.028194 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0280859 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0279827 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0278865 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0277914 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0277307 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0271805 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0267433 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.026203 |
| KLF12 | Kruppel-like factor 12 | 0.0260196 |
| SATB2 | SATB homeobox 2 | 0.0260108 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0259313 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0258587 |
| SEPTIN2 | septin 2 | 0.0255355 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0254832 |
| TXNRD1 | thioredoxin reductase 1 | 0.0254384 |
| TMF1 | TATA element modulatory factor 1 | 0.0240522 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0238877 |
| RBM33 | RNA binding motif protein 33 | 0.0237712 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.023753 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0236209 |
| USP37 | ubiquitin specific peptidase 37 | 0.0235203 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0233994 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0233733 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0233149 |
| ITGA6 | integrin, alpha 6 | 0.0230984 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0230227 |
| RBM25 | RNA binding motif protein 25 | 0.0229159 |
| FTO | fat mass and obesity associated | 0.022865 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.0228469 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0228192 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0225588 |
| TRRAP | transformation/transcription domain-associated protein | 0.0224843 |
| ZNF292 | zinc finger protein 292 | 0.0224213 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.022148 |
| ATP9B | ATPase, class II, type 9B | 0.021959 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0219036 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0217786 |
| ZNF638 | zinc finger protein 638 | 0.0217391 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0216898 |
| RAB21 | RAB21, member RAS oncogene family | 0.0216383 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0215378 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0215322 |
| SDC2 | syndecan 2 | 0.0215078 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0214557 |
| UBAC2 | UBA domain containing 2 | 0.0214311 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0213392 |
| KLC1 | kinesin light chain 1 | 0.0212435 |
| CORO1C | coronin, actin binding protein, 1C | 0.0212146 |
| MYO9A | myosin IXA | 0.0211112 |
| HELZ | helicase with zinc finger | 0.0210839 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0209756 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0209473 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0209427 |
| TSPAN5 | tetraspanin 5 | 0.0209383 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0208483 |
| EGFR | epidermal growth factor receptor | 0.0208044 |
| CEP170 | centrosomal protein 170kDa | 0.0206278 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0206241 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 0.0205434 |
| FAM13A | family with sequence similarity 13, member A | 0.0204313 |
| JUN | jun proto-oncogene | 0.0204147 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0203407 |
| SLC35F2 | solute carrier family 35, member F2 | 0.0202509 |
| MSANTD4 | Myb/SANT-like DNA-binding domain containing 4 with coiled-coils | 0.0196197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.106858 |
| VIM | vimentin | -0.106833 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0996219 |
| HMGA2 | high mobility group AT-hook 2 | -0.0889402 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0877202 |
| LDHA | lactate dehydrogenase A | -0.0772985 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0691874 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0590401 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0548014 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.053531 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0517877 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0484341 |
| RPL37 | ribosomal protein L37 | -0.0483902 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0470908 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0451467 |
| RAI14 | retinoic acid induced 14 | -0.0443876 |
| EGR1 | early growth response 1 | -0.0440637 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0436059 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.041941 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0416589 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0416198 |
| HLA-B | major histocompatibility complex, class I, B | -0.0416155 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0414508 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0412536 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0408767 |
| INTS6 | integrator complex subunit 6 | -0.040663 |
| PTK2 | protein tyrosine kinase 2 | -0.0406343 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0406145 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0403254 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0400708 |
| HDAC9 | histone deacetylase 9 | -0.0396665 |
| GNAS | GNAS complex locus | -0.0392107 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0389096 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0369879 |
| RAD51B | RAD51 paralog B | -0.0368476 |
| POTEF | POTE ankyrin domain family, member F | -0.0366498 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0363191 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0360354 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0358539 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0355578 |
| RPL35A | ribosomal protein L35a | -0.035076 |
| FMN1 | formin 1 | -0.0349487 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0347247 |
| SCFD1 | sec1 family domain containing 1 | -0.0341977 |
| AOPEP | aminopeptidase O (putative) | -0.0333872 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0327876 |
| RPL31 | ribosomal protein L31 | -0.0326363 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0323658 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.032321 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0321596 |
| VCL | vinculin | -0.0320667 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0319663 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0317762 |
| PARD3 | par-3 family cell polarity regulator | -0.0313796 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0307203 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0304536 |
| TAOK3 | TAO kinase 3 | -0.0300579 |
| RPS8 | ribosomal protein S8 | -0.030028 |
| GPHN | gephyrin | -0.0299142 |
| FNIP1 | folliculin interacting protein 1 | -0.0297702 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0289958 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0289538 |
| IER3 | immediate early response 3 | -0.0286735 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0286264 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0281888 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0279578 |
| RPS13 | ribosomal protein S13 | -0.0279496 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0271143 |
| MYO10 | myosin X | -0.0269687 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0269679 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0268929 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0267814 |
| RPLP1 | ribosomal protein, large, P1 | -0.0265992 |
| NF1 | neurofibromin 1 | -0.0265206 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0263666 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0263622 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0263225 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0260581 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0260445 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0259692 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0259368 |
| RTN3 | reticulon 3 | -0.0258252 |
| RDX | radixin | -0.0258186 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.025805 |
| USP15 | ubiquitin specific peptidase 15 | -0.0257206 |
| HM13 | histocompatibility (minor) 13 | -0.0256598 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0255995 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0255866 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0254639 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0253118 |
| OSMR | oncostatin M receptor | -0.0252112 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0250823 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0250799 |
| WDR70 | WD repeat domain 70 | -0.0247239 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.024697 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0246686 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0246099 |
| MYO1E | myosin IE | -0.0246078 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0239185 |
| CDK12 | cyclin-dependent kinase 12 | -0.023821 |
