| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.102772 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0908044 |
| ASPH | aspartate beta-hydroxylase | 0.0824888 |
| TMSB10 | thymosin beta 10 | 0.0761511 |
| PTMA | prothymosin, alpha | 0.0683311 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0659294 |
| VIM | vimentin | 0.060437 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0588869 |
| B2M | beta-2-microglobulin | 0.0570166 |
| SEPTIN9 | septin 9 | 0.0554335 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0542035 |
| HLA-B | major histocompatibility complex, class I, B | 0.0533883 |
| MT2A | metallothionein 2A | 0.0532574 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0523705 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0500546 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.049259 |
| FTL | ferritin, light polypeptide | 0.0476773 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0471484 |
| VCL | vinculin | 0.0465263 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0463634 |
| TOP1 | topoisomerase (DNA) I | 0.0438156 |
| S100A6 | S100 calcium binding protein A6 | 0.04262 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.042532 |
| SFTPA2 | surfactant protein A2 | 0.0403448 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0386592 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.037819 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0376921 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0376489 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0362789 |
| TPI1 | triosephosphate isomerase 1 | 0.0336544 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0335486 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0332421 |
| S100A10 | S100 calcium binding protein A10 | 0.0322785 |
| PLEC | plectin | 0.0316995 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.031344 |
| MYOF | myoferlin | 0.0311661 |
| LMNA | lamin A/C | 0.0311435 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.030916 |
| RPS12 | ribosomal protein S12 | 0.0308039 |
| INTS6 | integrator complex subunit 6 | 0.0304056 |
| AHNAK | AHNAK nucleoprotein | 0.0303899 |
| RPL26 | ribosomal protein L26 | 0.0300732 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0299467 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0297587 |
| TMSB4X | thymosin beta 4, X-linked | 0.0295255 |
| BPTF | bromodomain PHD finger transcription factor | 0.02896 |
| FERMT2 | fermitin family member 2 | 0.0286817 |
| SPAG9 | sperm associated antigen 9 | 0.0283998 |
| NTN4 | netrin 4 | 0.0283653 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0280241 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0277011 |
| RPS6 | ribosomal protein S6 | 0.027334 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0271497 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0269924 |
| RPS3 | ribosomal protein S3 | 0.0268224 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0267904 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0265026 |
| RPS19 | ribosomal protein S19 | 0.0263779 |
| RAB31 | RAB31, member RAS oncogene family | 0.0261284 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0259377 |
| AFDN | afadin, adherens junction formation factor | 0.0251375 |
| FAT1 | FAT atypical cadherin 1 | 0.0251366 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0248632 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0247248 |
| SMAD3 | SMAD family member 3 | 0.0245021 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0243268 |
| GOLGB1 | golgin B1 | 0.0242674 |
| RPS27A | ribosomal protein S27a | 0.0241057 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0240527 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0239646 |
| RPS27 | ribosomal protein S27 | 0.0237037 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0235152 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0234225 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0232962 |
| NPTN | neuroplastin | 0.0232488 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0229128 |
| RPL23 | ribosomal protein L23 | 0.0226561 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0222557 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0222261 |
| TXNIP | thioredoxin interacting protein | 0.0221251 |
| PGK1 | phosphoglycerate kinase 1 | 0.022041 |
| PLIN2 | perilipin 2 | 0.0218793 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0214531 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0214192 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0213875 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0213668 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0211983 |
| ACTN4 | actinin, alpha 4 | 0.0209396 |
| RPL37A | ribosomal protein L37a | 0.0208147 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0206606 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0204566 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0203446 |
| KLF10 | Kruppel-like factor 10 | 0.0201436 |
| GPATCH2L | G patch domain containing 2-like | 0.0200728 |
| SMYD3 | SET and MYND domain containing 3 | 0.0200016 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0199912 |
| WDR33 | WD repeat domain 33 | 0.0198554 |
| FLNA | filamin A, alpha | 0.019685 |
| XPO1 | exportin 1 | 0.0192095 |
| RPL19 | ribosomal protein L19 | 0.019089 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.268199 |
| NRG1 | neuregulin 1 | -0.240244 |
| TMEM156 | transmembrane protein 156 | -0.121271 |
| EFNA5 | ephrin-A5 | -0.114494 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.104384 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0892804 |
| ITGA1 | integrin, alpha 1 | -0.0860919 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0831017 |
| GLIS3 | GLIS family zinc finger 3 | -0.0775104 |
| FN1 | fibronectin 1 | -0.0774291 |
| SYT1 | synaptotagmin I | -0.0726956 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0635188 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0573006 |
| KLHL5 | kelch-like family member 5 | -0.0570604 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.056756 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0559255 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0552767 |
| HMGA2 | high mobility group AT-hook 2 | -0.0534599 |
| ETV6 | ets variant 6 | -0.0504189 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0469453 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0425236 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0405218 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0386967 |
| OSMR | oncostatin M receptor | -0.0386334 |
| NRP1 | neuropilin 1 | -0.0381896 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0362724 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0362355 |
| RUNX2 | runt-related transcription factor 2 | -0.0358734 |
| FOXP1 | forkhead box P1 | -0.0355836 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0354526 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0346313 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0344105 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0338748 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0338174 |
| AOPEP | aminopeptidase O (putative) | -0.0332493 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0328717 |
| TNS3 | tensin 3 | -0.0315963 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.031585 |
| TXNRD1 | thioredoxin reductase 1 | -0.0312269 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0301983 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0301405 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.029034 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0289797 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0288838 |
| MX1 | MX dynamin-like GTPase 1 | -0.0286999 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0279081 |
| VMP1 | vacuole membrane protein 1 | -0.0274704 |
| STC2 | stanniocalcin 2 | -0.0274691 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0274597 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0273035 |
| CADM1 | cell adhesion molecule 1 | -0.027296 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0272046 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0269852 |
| AHI1 | Abelson helper integration site 1 | -0.0266153 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0264121 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0262684 |
| RAI14 | retinoic acid induced 14 | -0.0260452 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0256441 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0254905 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0247165 |
| TGFA | transforming growth factor, alpha | -0.024319 |
| RANBP17 | RAN binding protein 17 | -0.0241892 |
| UBXN4 | UBX domain protein 4 | -0.0239206 |
| FBN1 | fibrillin 1 | -0.0235891 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0232546 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0232461 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0230621 |
| DENND5B | DENN/MADD domain containing 5B | -0.0229909 |
| ARF4 | ADP-ribosylation factor 4 | -0.022282 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0220026 |
| CD109 | CD109 molecule | -0.0218922 |
| HPCAL1 | hippocalcin-like 1 | -0.0215728 |
| DHFR | dihydrofolate reductase | -0.0214453 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0214167 |
| ATP9A | ATPase, class II, type 9A | -0.0213228 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0210773 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0209468 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0199585 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0198955 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0198819 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0198335 |
| PDGFC | platelet derived growth factor C | -0.0197984 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0197975 |
| FBXO32 | F-box protein 32 | -0.0196213 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0195482 |
| BICC1 | BicC family RNA binding protein 1 | -0.0195132 |
| COG5 | component of oligomeric golgi complex 5 | -0.0194923 |
| PLSCR1 | phospholipid scramblase 1 | -0.0193952 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0193389 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0191623 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0190782 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0189574 |
| RIGI | RNA sensor RIG-I | -0.018862 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0187763 |
| PCED1B | PC-esterase domain containing 1B | -0.0186937 |
| FAM20C | family with sequence similarity 20, member C | -0.0185091 |
| TMEM263 | transmembrane protein 263 | -0.0184673 |
| WDR27 | WD repeat domain 27 | -0.0183415 |
| PELO | pelota homolog (Drosophila) | -0.0180424 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0180097 |