| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.117794 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0770698 |
| PLEC | plectin | 0.0768095 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0698209 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0674401 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0660717 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0659965 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0636887 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0612553 |
| VCL | vinculin | 0.0582364 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0580989 |
| SMAD3 | SMAD family member 3 | 0.0575826 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0562787 |
| DSPP | dentin sialophosphoprotein | 0.0554981 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0518092 |
| FLNA | filamin A, alpha | 0.0504613 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0489654 |
| CTBP2 | C-terminal binding protein 2 | 0.0464171 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0463854 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0453283 |
| MYO1E | myosin IE | 0.0446549 |
| TUFT1 | tuftelin 1 | 0.0441204 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0439158 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0436686 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0436241 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0431218 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0427784 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.041007 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0404849 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0404486 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0396757 |
| CUL3 | cullin 3 | 0.0384668 |
| RPLP1 | ribosomal protein, large, P1 | 0.0373331 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0357152 |
| STX3 | syntaxin 3 | 0.035342 |
| FAM107B | family with sequence similarity 107, member B | 0.0347542 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0338351 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0338086 |
| RBM39 | RNA binding motif protein 39 | 0.0334011 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0332617 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0332061 |
| AFDN | afadin, adherens junction formation factor | 0.0331775 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0329266 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0318425 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0316163 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0315334 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0314186 |
| ASPH | aspartate beta-hydroxylase | 0.0306054 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0305408 |
| YAP1 | Yes-associated protein 1 | 0.0301927 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0299948 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0296294 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0295137 |
| RPL23 | ribosomal protein L23 | 0.0294313 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0292071 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0290471 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0290168 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0289525 |
| INTS6 | integrator complex subunit 6 | 0.028945 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0287929 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0283883 |
| ACTN1 | actinin, alpha 1 | 0.028221 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0279338 |
| MED13L | mediator complex subunit 13-like | 0.0273198 |
| TJP1 | tight junction protein 1 | 0.0272623 |
| BRD2 | bromodomain containing 2 | 0.0272613 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0272446 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0272293 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0272118 |
| SQSTM1 | sequestosome 1 | 0.027021 |
| GNAS | GNAS complex locus | 0.0268925 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.026755 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.026698 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.026365 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0263057 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0258357 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0258129 |
| USP53 | ubiquitin specific peptidase 53 | 0.0257628 |
| GOLGB1 | golgin B1 | 0.0256453 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0254715 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0253208 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0250342 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0248175 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0247626 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0244419 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0244215 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0243168 |
| RPL35A | ribosomal protein L35a | 0.0242749 |
| RPS6 | ribosomal protein S6 | 0.0240638 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0236464 |
| NPTN | neuroplastin | 0.0236302 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0235738 |
| JUN | jun proto-oncogene | 0.0234135 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0230527 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0229856 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.02294 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0229124 |
| FUS | FUS RNA binding protein | 0.0228923 |
| CCNYL1 | cyclin Y-like 1 | 0.0227972 |
| RPS27A | ribosomal protein S27a | 0.0227891 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | -0.154979 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.132951 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0959916 |
| EHBP1 | EH domain binding protein 1 | -0.0870535 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0781172 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0749556 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0746402 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0722621 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0601518 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0569326 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0568354 |
| EGR1 | early growth response 1 | -0.0544009 |
| LDHA | lactate dehydrogenase A | -0.0542055 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0527786 |
| EXOC4 | exocyst complex component 4 | -0.0482047 |
| FRMD5 | FERM domain containing 5 | -0.0461405 |
| PERP | PERP, TP53 apoptosis effector | -0.0461126 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0421614 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0416194 |
| NFIA | nuclear factor I/A | -0.0405989 |
| FTL | ferritin, light polypeptide | -0.0405159 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0389837 |
| UBC | ubiquitin C | -0.0388268 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0381159 |
| TMEM123 | transmembrane protein 123 | -0.0380972 |
| CLDN4 | claudin 4 | -0.0379721 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0378207 |
| MYOF | myoferlin | -0.0366772 |
| TBC1D5 | TBC1 domain family, member 5 | -0.036209 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.034775 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0338377 |
| PLSCR1 | phospholipid scramblase 1 | -0.033591 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0335013 |
| PKP4 | plakophilin 4 | -0.0334032 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0325599 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0325358 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0323288 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0312989 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.03052 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0302087 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0299978 |
| ITGB4 | integrin, beta 4 | -0.029649 |
| THOC2 | THO complex 2 | -0.0283484 |
| NDRG1 | N-myc downstream regulated 1 | -0.0282631 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0282235 |
| POTEF | POTE ankyrin domain family, member F | -0.028145 |
| FNBP4 | formin binding protein 4 | -0.0273199 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.02656 |
| NF1 | neurofibromin 1 | -0.0265305 |
| PRELID2 | PRELI domain containing 2 | -0.0264711 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.025712 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0255495 |
| PTK2 | protein tyrosine kinase 2 | -0.024911 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0248572 |
| CUX1 | cut-like homeobox 1 | -0.0245583 |
| HLA-A | major histocompatibility complex, class I, A | -0.0242939 |
| ECT2 | epithelial cell transforming 2 | -0.0241958 |
| HMGA1 | high mobility group AT-hook 1 | -0.0240789 |
| PHF14 | PHD finger protein 14 | -0.0238989 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.023838 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.023717 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0234849 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | -0.0231734 |
| ANXA2 | annexin A2 | -0.0230813 |
| DACH1 | dachshund family transcription factor 1 | -0.0227449 |
| CCND1 | cyclin D1 | -0.0225471 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0224344 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0223363 |
| HDAC9 | histone deacetylase 9 | -0.0221623 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0220119 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0218239 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0217703 |
| MX2 | MX dynamin-like GTPase 2 | -0.0214406 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0213138 |
| TCF12 | transcription factor 12 | -0.0209169 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.020803 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0206653 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0205592 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0205163 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0204962 |
| SNX9 | sorting nexin 9 | -0.0204757 |
| CD2AP | CD2-associated protein | -0.0203999 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0203527 |
| CADPS | Ca++-dependent secretion activator | -0.020332 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0203024 |
| TOB1 | transducer of ERBB2, 1 | -0.0202685 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0200569 |
| RFX7 | regulatory factor X, 7 | -0.0200447 |
| RPS13 | ribosomal protein S13 | -0.0198538 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0196952 |
| PTEN | phosphatase and tensin homolog | -0.0196761 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0196239 |
| CLDN3 | claudin 3 | -0.019556 |
| ZNRF3 | zinc and ring finger 3 | -0.0195188 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0195138 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0195041 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0194293 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0193848 |
| SRRM3 | serine/arginine repetitive matrix 3 | -0.0192839 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0189765 |
