| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clonidine (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.0891184 |
| ANXA1 | annexin A1 | 0.0759299 |
| DSPP | dentin sialophosphoprotein | 0.0646602 |
| RAD51B | RAD51 paralog B | 0.0640491 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0611557 |
| LMO7 | LIM domain 7 | 0.0601259 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0569538 |
| EGFR | epidermal growth factor receptor | 0.0553029 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0512036 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0470098 |
| LAMA4 | laminin, alpha 4 | 0.0466577 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0458701 |
| RPL3 | ribosomal protein L3 | 0.0457398 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0448822 |
| LAMC2 | laminin, gamma 2 | 0.0437366 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0418851 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0415855 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0414329 |
| SEPTIN9 | septin 9 | 0.041246 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0395084 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0373121 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0358574 |
| BCL2L1 | BCL2-like 1 | 0.035229 |
| EHBP1 | EH domain binding protein 1 | 0.0311461 |
| CTSB | cathepsin B | 0.0309773 |
| VCL | vinculin | 0.0308823 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0308724 |
| CPOX | coproporphyrinogen oxidase | 0.0303107 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0300658 |
| LAMB3 | laminin, beta 3 | 0.0289751 |
| H1-4 | H1.4 linker histone, cluster member | 0.0288763 |
| EPHA2 | EPH receptor A2 | 0.0283595 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0281178 |
| FHL2 | four and a half LIM domains 2 | 0.0280867 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0266854 |
| DST | dystonin | 0.025981 |
| ATXN1 | ataxin 1 | 0.0258273 |
| CLDND1 | claudin domain containing 1 | 0.0256236 |
| RPS2 | ribosomal protein S2 | 0.0251671 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0250526 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0247879 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0245693 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.024488 |
| MYOF | myoferlin | 0.0241155 |
| SERINC5 | serine incorporator 5 | 0.0240099 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0224032 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0222285 |
| PRELID2 | PRELI domain containing 2 | 0.0219819 |
| MACROD2 | MACRO domain containing 2 | 0.0219059 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0217751 |
| IER2 | immediate early response 2 | 0.0216299 |
| H1-2 | H1.2 linker histone, cluster member | 0.0213735 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0212336 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0210521 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.0206563 |
| PLAUR | plasminogen activator, urokinase receptor | 0.020646 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0203744 |
| RPL4 | ribosomal protein L4 | 0.0202798 |
| YME1L1 | YME1-like 1 ATPase | 0.020261 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0202211 |
| ATL2 | atlastin GTPase 2 | 0.0201702 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0201252 |
| ZNF146 | zinc finger protein 146 | 0.0200238 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0198799 |
| SLC30A10 | solute carrier family 30, member 10 | 0.0198193 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.0198095 |
| RPL41 | ribosomal protein L41 | 0.0197011 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0194083 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0193578 |
| DSG2 | desmoglein 2 | 0.0192116 |
| EFNA5 | ephrin-A5 | 0.0192 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0191037 |
| PYGL | phosphorylase, glycogen, liver | 0.0188596 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0187027 |
| CEP290 | centrosomal protein 290kDa | 0.0186689 |
| TENM3 | teneurin transmembrane protein 3 | 0.0185923 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 | 0.0184877 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0183023 |
| EFNB2 | ephrin-B2 | 0.0182793 |
| TRIM44 | tripartite motif containing 44 | 0.0181035 |
| FTO | fat mass and obesity associated | 0.0179563 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0178475 |
| KLC1 | kinesin light chain 1 | 0.0178286 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0177877 |
| HDAC4 | histone deacetylase 4 | 0.0176944 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0175969 |
| ECT2 | epithelial cell transforming 2 | 0.0174356 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.017197 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0171327 |
| GOLGB1 | golgin B1 | 0.0171273 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.017123 |
| SFTPA2 | surfactant protein A2 | 0.0169092 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | 0.0167586 |
| ARRDC3 | arrestin domain containing 3 | 0.0166988 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.016588 |
| TES | testin LIM domain protein | 0.0165534 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.0165115 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0164878 |
| EXOC4 | exocyst complex component 4 | 0.0162073 |
| TPI1 | triosephosphate isomerase 1 | 0.0161909 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166135 |
| PTMA | prothymosin, alpha | -0.135548 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.124868 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.12269 |
| TMSB10 | thymosin beta 10 | -0.109508 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.106433 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.10628 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.104871 |
| ACTG1 | actin gamma 1 | -0.0957478 |
| EGR1 | early growth response 1 | -0.0951629 |
| UBC | ubiquitin C | -0.0798943 |
| PCBP2 | poly(rC) binding protein 2 | -0.0791434 |
| NDRG1 | N-myc downstream regulated 1 | -0.0789407 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.078843 |
| GOLGA4 | golgin A4 | -0.0775716 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0728232 |
| RPS27A | ribosomal protein S27a | -0.0694787 |
| AREG | amphiregulin | -0.0665794 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0658492 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0637778 |
| RPS6 | ribosomal protein S6 | -0.0636661 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0623332 |
| RPL5 | ribosomal protein L5 | -0.061048 |
| COG5 | component of oligomeric golgi complex 5 | -0.0606897 |
| RREB1 | ras responsive element binding protein 1 | -0.0599988 |
| RBM25 | RNA binding motif protein 25 | -0.0592952 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0560736 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0556385 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.054281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0535241 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0518349 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0505009 |
| RPL37A | ribosomal protein L37a | -0.0497882 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0474662 |
| S100A6 | S100 calcium binding protein A6 | -0.0473179 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0470581 |
| RPS29 | ribosomal protein S29 | -0.0470078 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0459177 |
| IER3 | immediate early response 3 | -0.0444153 |
| LDHA | lactate dehydrogenase A | -0.0442724 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0442026 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0441106 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0435353 |
| SBF2 | SET binding factor 2 | -0.0429093 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0425077 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0422443 |
| ENO1 | enolase 1, (alpha) | -0.0420642 |
| SETD5 | SET domain containing 5 | -0.0417788 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.041555 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0414839 |
| POTEF | POTE ankyrin domain family, member F | -0.041389 |
| RCOR1 | REST corepressor 1 | -0.0409365 |
| ITGB4 | integrin, beta 4 | -0.0405346 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0403624 |
| RPS8 | ribosomal protein S8 | -0.0402009 |
| RPL35A | ribosomal protein L35a | -0.03999 |
| RPS3 | ribosomal protein S3 | -0.0397587 |
| ZNF207 | zinc finger protein 207 | -0.0396979 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0395426 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0394706 |
| RPS24 | ribosomal protein S24 | -0.0390336 |
| EZR | ezrin | -0.0384518 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0384299 |
| TOP1 | topoisomerase (DNA) I | -0.0384148 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0379086 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0375821 |
| MTDH | metadherin | -0.0371131 |
| HMGA1 | high mobility group AT-hook 1 | -0.037084 |
| ANXA11 | annexin A11 | -0.0370413 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0368051 |
| FERMT1 | fermitin family member 1 | -0.0367589 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0363753 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0356832 |
| SCFD1 | sec1 family domain containing 1 | -0.0356502 |
| IGF2 | insulin-like growth factor 2 | -0.035599 |
| NEMF | nuclear export mediator factor | -0.0353137 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0350686 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0344004 |
| RPS25 | ribosomal protein S25 | -0.0338895 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.033818 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0337463 |
| NAV2 | neuron navigator 2 | -0.0336836 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0329577 |
| RPL9 | ribosomal protein L9 | -0.0328293 |
| ANXA2 | annexin A2 | -0.032268 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0321635 |
| RBM33 | RNA binding motif protein 33 | -0.0318315 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0316587 |
| MSI2 | musashi RNA-binding protein 2 | -0.031648 |
| CBX3 | chromobox homolog 3 | -0.0311317 |
| RBM39 | RNA binding motif protein 39 | -0.0310233 |
| S100A10 | S100 calcium binding protein A10 | -0.0309575 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0308926 |
| FMNL2 | formin-like 2 | -0.0308235 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0307826 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0306965 |
| RPL36 | ribosomal protein L36 | -0.0306625 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0305283 |
| HDAC2 | histone deacetylase 2 | -0.0304003 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0299954 |
