| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clonidine (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clonidine (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.100312 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0847602 |
| HMGA2 | high mobility group AT-hook 2 | 0.0606361 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0602816 |
| INTS6 | integrator complex subunit 6 | 0.0592307 |
| ASPH | aspartate beta-hydroxylase | 0.0569237 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0554814 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0526096 |
| VCL | vinculin | 0.0486472 |
| PRELID2 | PRELI domain containing 2 | 0.0414491 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0383264 |
| GLIS3 | GLIS family zinc finger 3 | 0.038103 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0380381 |
| NAV1 | neuron navigator 1 | 0.035317 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0351683 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0350335 |
| NAV2 | neuron navigator 2 | 0.0345887 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0321536 |
| MSN | moesin | 0.0311417 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0287291 |
| RASA2 | RAS p21 protein activator 2 | 0.0283966 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0282227 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0279197 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0272129 |
| MYO10 | myosin X | 0.0268479 |
| CLIC4 | chloride intracellular channel 4 | 0.0250462 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0240643 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0233429 |
| FLNA | filamin A, alpha | 0.0229692 |
| PLEC | plectin | 0.0225246 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0225186 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0213013 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0210615 |
| RCOR1 | REST corepressor 1 | 0.0207222 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0206276 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0200612 |
| ACTN1 | actinin, alpha 1 | 0.0196119 |
| ZNF638 | zinc finger protein 638 | 0.0194765 |
| AEBP2 | AE binding protein 2 | 0.0193919 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0191413 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0190815 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0190178 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0186689 |
| DGKI | diacylglycerol kinase, iota | 0.0186676 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0183273 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0183038 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0182758 |
| IPO9 | importin 9 | 0.0182112 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0180698 |
| MCL1 | myeloid cell leukemia 1 | 0.0179835 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0179114 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0178028 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0175889 |
| NABP1 | nucleic acid binding protein 1 | 0.0173607 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0173094 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0169768 |
| TLE4 | transducin-like enhancer of split 4 | 0.0167262 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0165606 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0165389 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0165033 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.016183 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | 0.0161738 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0161347 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0161255 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0160434 |
| FGF5 | fibroblast growth factor 5 | 0.0159489 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0158089 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0155135 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0154413 |
| EGFR | epidermal growth factor receptor | 0.0153912 |
| FMNL2 | formin-like 2 | 0.0153705 |
| HSPA8 | heat shock 70kDa protein 8 | 0.015207 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0150512 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0150077 |
| ATG7 | autophagy related 7 | 0.0149942 |
| KLF12 | Kruppel-like factor 12 | 0.0143981 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0143322 |
| ANO6 | anoctamin 6 | 0.0139035 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0138168 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0137798 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0137251 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.013536 |
| GLRX | glutaredoxin (thioltransferase) | 0.013367 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0133378 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.0133206 |
| TOP1 | topoisomerase (DNA) I | 0.0132939 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0132109 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0131142 |
| GPATCH2L | G patch domain containing 2-like | 0.0129089 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0129058 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0127627 |
| BRD2 | bromodomain containing 2 | 0.0127135 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0125664 |
| KLC1 | kinesin light chain 1 | 0.0125586 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0124968 |
| JAK1 | Janus kinase 1 | 0.0123015 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0122068 |
| PRKCE | protein kinase C, epsilon | 0.0121845 |
| CAPRIN2 | caprin family member 2 | 0.0121788 |
| TTC23L | tetratricopeptide repeat domain 23-like | 0.0121431 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.447288 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.291309 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.140872 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.117679 |
| NDRG1 | N-myc downstream regulated 1 | -0.107135 |
| INHBA | inhibin, beta A | -0.100514 |
| FN1 | fibronectin 1 | -0.0959106 |
| STC1 | stanniocalcin 1 | -0.086835 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0830887 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0829219 |
| MMP1 | matrix metallopeptidase 1 | -0.0798437 |
| COL1A1 | collagen, type I, alpha 1 | -0.0789879 |
| HLA-B | major histocompatibility complex, class I, B | -0.0777505 |
| COL1A2 | collagen, type I, alpha 2 | -0.0763048 |
| FTL | ferritin, light polypeptide | -0.0756963 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0692072 |
| B2M | beta-2-microglobulin | -0.0649956 |
| ATP13A3 | ATPase type 13A3 | -0.0649846 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0609641 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0604588 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0583682 |
| TMSB10 | thymosin beta 10 | -0.0536772 |
| GOLGA4 | golgin A4 | -0.0517257 |
| FAM13A | family with sequence similarity 13, member A | -0.0516414 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0515401 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0507532 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0505398 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.050371 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0484306 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.04742 |
| ADM | adrenomedullin | -0.0466273 |
| EMP1 | epithelial membrane protein 1 | -0.0465947 |
| RPS6 | ribosomal protein S6 | -0.0458323 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0446837 |
| MMP12 | matrix metallopeptidase 12 | -0.0441578 |
| LDHA | lactate dehydrogenase A | -0.0427126 |
| HLA-A | major histocompatibility complex, class I, A | -0.0417223 |
| PTMA | prothymosin, alpha | -0.0416088 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.040318 |
| S100A6 | S100 calcium binding protein A6 | -0.0401077 |
| TPM4 | tropomyosin 4 | -0.0399336 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0397785 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0392118 |
| ANXA2 | annexin A2 | -0.0383114 |
| CALR | calreticulin | -0.0376804 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0366466 |
| OXR1 | oxidation resistance 1 | -0.0362287 |
| RPLP1 | ribosomal protein, large, P1 | -0.0359521 |
| TMEM165 | transmembrane protein 165 | -0.0356308 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0352082 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0349459 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0339921 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0339645 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0337091 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0336336 |
| CD44 | CD44 molecule (Indian blood group) | -0.0327619 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0324651 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0318812 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0315067 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0308882 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0304186 |
| LOX | lysyl oxidase | -0.0290309 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0289544 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0284993 |
| CLMP | CXADR-like membrane protein | -0.0273337 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0269385 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.026614 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0264324 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0262211 |
| RTN4 | reticulon 4 | -0.0261466 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0259389 |
| RPS8 | ribosomal protein S8 | -0.0253556 |
| CANX | calnexin | -0.0247586 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0245996 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0240418 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0239769 |
| MAP1B | microtubule-associated protein 1B | -0.023547 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0235073 |
| RAI14 | retinoic acid induced 14 | -0.0231485 |
| PRRX1 | paired related homeobox 1 | -0.0229308 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0228435 |
| RPL34 | ribosomal protein L34 | -0.0227413 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0222126 |
| FBN1 | fibrillin 1 | -0.022055 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0220491 |
| RND3 | Rho family GTPase 3 | -0.0215628 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0214059 |
| RPL35A | ribosomal protein L35a | -0.0212944 |
| WASF2 | WAS protein family, member 2 | -0.0211291 |
| RPS13 | ribosomal protein S13 | -0.0209523 |
| SRP54 | signal recognition particle 54kDa | -0.0209356 |
| USP3 | ubiquitin specific peptidase 3 | -0.020914 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0208717 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0208443 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0207387 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0206327 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0205563 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0205362 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0205211 |
| PKM | pyruvate kinase, muscle | -0.0204415 |
