| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clopidogrel perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clopidogrel_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0950051 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0645106 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0600923 |
| SPAG9 | sperm associated antigen 9 | 0.0507133 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0435415 |
| LDHA | lactate dehydrogenase A | 0.042493 |
| ATP13A3 | ATPase type 13A3 | 0.0390211 |
| CADM1 | cell adhesion molecule 1 | 0.0359632 |
| ZNF292 | zinc finger protein 292 | 0.0327688 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0306026 |
| RASA2 | RAS p21 protein activator 2 | 0.0302778 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0301154 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0299014 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0297309 |
| YBX1 | Y box binding protein 1 | 0.0286318 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0274343 |
| OGA | O-GlcNAcase | 0.0266127 |
| MRTFA | myocardin related transcription factor A | 0.0262146 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0258152 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.025793 |
| RLF | rearranged L-myc fusion | 0.0256503 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.025333 |
| RPS8 | ribosomal protein S8 | 0.0251962 |
| SQLE | squalene epoxidase | 0.0240413 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0239513 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0237408 |
| RPS12 | ribosomal protein S12 | 0.0237245 |
| SMAD3 | SMAD family member 3 | 0.0236093 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.02342 |
| MT1X | metallothionein 1X | 0.0229218 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0221516 |
| RPS3 | ribosomal protein S3 | 0.0221451 |
| ANXA2 | annexin A2 | 0.0219614 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0218367 |
| FMNL2 | formin-like 2 | 0.0218179 |
| ARRDC3 | arrestin domain containing 3 | 0.0207807 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0206369 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0204479 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0201929 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0197946 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0197668 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0194235 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0193529 |
| TFG | TRK-fused gene | 0.0190633 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0187858 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0187629 |
| GOLGA4 | golgin A4 | 0.0186687 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0186601 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0185242 |
| RPL7 | ribosomal protein L7 | 0.0185103 |
| CAVIN1 | caveolae associated protein 1 | 0.0183813 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0181761 |
| CLINT1 | clathrin interactor 1 | 0.0181601 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0177131 |
| RPL26 | ribosomal protein L26 | 0.0174497 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0174254 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.017311 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0170088 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0169682 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0169149 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0168876 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0168389 |
| USP3 | ubiquitin specific peptidase 3 | 0.0168288 |
| RPL12 | ribosomal protein L12 | 0.0166291 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0164385 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0161377 |
| RACK1 | receptor for activated C kinase 1 | 0.0160161 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0160054 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0158682 |
| PTK2 | protein tyrosine kinase 2 | 0.0156249 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0156226 |
| QKI | QKI, KH domain containing, RNA binding | 0.0155968 |
| RPL19 | ribosomal protein L19 | 0.0155716 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0153819 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0153787 |
| RPLP1 | ribosomal protein, large, P1 | 0.0153167 |
| HIP1 | huntingtin interacting protein 1 | 0.0149558 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0147551 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0145406 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0145037 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0143272 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0143093 |
| CALR | calreticulin | 0.0143001 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0141119 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0139469 |
| RPL30 | ribosomal protein L30 | 0.0138436 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0138177 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0137496 |
| NKTR | natural killer cell triggering receptor | 0.0135273 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0134691 |
| FAM13B | family with sequence similarity 13, member B | 0.0132547 |
| B2M | beta-2-microglobulin | 0.0131645 |
| KIF1B | kinesin family member 1B | 0.0131617 |
| NAV2 | neuron navigator 2 | 0.0131438 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0130934 |
| RHEB | Ras homolog enriched in brain | 0.0129731 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0129452 |
| TMSB4X | thymosin beta 4, X-linked | 0.0129362 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0129038 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0127964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.307373 |
| FN1 | fibronectin 1 | -0.17135 |
| COL1A1 | collagen, type I, alpha 1 | -0.144052 |
| CDH13 | cadherin 13 | -0.0823563 |
| COL1A2 | collagen, type I, alpha 2 | -0.0734784 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.058608 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0562966 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0539253 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0504238 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0488156 |
| VEGFA | vascular endothelial growth factor A | -0.0470012 |
| NDRG1 | N-myc downstream regulated 1 | -0.0467865 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0452248 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0426328 |
| FBN1 | fibrillin 1 | -0.0412958 |
| DPYD | dihydropyrimidine dehydrogenase | -0.041205 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0395288 |
| COL5A1 | collagen, type V, alpha 1 | -0.034743 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0338449 |
| GLIS3 | GLIS family zinc finger 3 | -0.0334935 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0331793 |
| VCAN | versican | -0.0330623 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0326721 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.032226 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0307968 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0291846 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.029013 |
| TMSB10 | thymosin beta 10 | -0.0288744 |
| ACTG1 | actin gamma 1 | -0.0276747 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0268918 |
| ASPH | aspartate beta-hydroxylase | -0.026527 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0262384 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0256407 |
| CALD1 | caldesmon 1 | -0.0252137 |
| COL6A1 | collagen, type VI, alpha 1 | -0.025084 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0231965 |
| CLMP | CXADR-like membrane protein | -0.0226527 |
| MAP1B | microtubule-associated protein 1B | -0.0220208 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0220065 |
| NRP1 | neuropilin 1 | -0.0201134 |
| POTEF | POTE ankyrin domain family, member F | -0.019945 |
| FOXP1 | forkhead box P1 | -0.0198807 |
| HLA-B | major histocompatibility complex, class I, B | -0.0195727 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0195656 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0189702 |
| IL6 | interleukin 6 | -0.017605 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0175152 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0173531 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0172793 |
| NAV1 | neuron navigator 1 | -0.0167685 |
| GOLGB1 | golgin B1 | -0.0167616 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0167012 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0163854 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.016291 |
| EGR1 | early growth response 1 | -0.0160624 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0159216 |
| CNTN5 | contactin 5 | -0.0156824 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0156071 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0152988 |
| BNC2 | basonuclin 2 | -0.0152155 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0150331 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.01461 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0145583 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0144623 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0143839 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0139209 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0138273 |
| TPM4 | tropomyosin 4 | -0.0138016 |
| TENM3 | teneurin transmembrane protein 3 | -0.0131873 |
| CCDC80 | coiled-coil domain containing 80 | -0.0130787 |
| CTSB | cathepsin B | -0.0129967 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0128578 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0127719 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0126272 |
| HLA-A | major histocompatibility complex, class I, A | -0.0125821 |
| CUX1 | cut-like homeobox 1 | -0.012519 |
| EGFR | epidermal growth factor receptor | -0.0124586 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0123058 |
| HMCN1 | hemicentin 1 | -0.0122759 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0122262 |
| OSMR | oncostatin M receptor | -0.012122 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0119909 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0119799 |
| SETBP1 | SET binding protein 1 | -0.0119489 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0118806 |
| PRKCA | protein kinase C, alpha | -0.0117989 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0117438 |
| VCL | vinculin | -0.0117241 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.011666 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0112622 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0112219 |
| RND3 | Rho family GTPase 3 | -0.011093 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0109496 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.010903 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0109008 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0107378 |
| NREP | neuronal regeneration related protein | -0.0106137 |
| LOX | lysyl oxidase | -0.0102832 |
| C1R | complement component 1, r subcomponent | -0.0101665 |
| CD99 | CD99 molecule | -0.0100591 |
