| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clopidogrel perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clopidogrel_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.161491 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.115765 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.112828 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0989 |
| ASPH | aspartate beta-hydroxylase | 0.0959447 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0938725 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0777063 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0744281 |
| ATXN1 | ataxin 1 | 0.0732086 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0710763 |
| ENO1 | enolase 1, (alpha) | 0.0684402 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.066382 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0645527 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0642136 |
| EHBP1 | EH domain binding protein 1 | 0.0632563 |
| FMNL2 | formin-like 2 | 0.0618267 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0577184 |
| DSPP | dentin sialophosphoprotein | 0.0552053 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0542618 |
| GPC6 | glypican 6 | 0.0529119 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0524829 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0519241 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.050326 |
| INTS6 | integrator complex subunit 6 | 0.0495805 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0485463 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0460884 |
| TF | transferrin | 0.0460499 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0457505 |
| FRMD5 | FERM domain containing 5 | 0.044663 |
| ARFGEF3 | ARFGEF family member 3 | 0.0439155 |
| DST | dystonin | 0.0420959 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0410261 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0403945 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0385945 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0384127 |
| RAD51B | RAD51 paralog B | 0.0377723 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0377332 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0374458 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0360963 |
| PEG3 | paternally expressed 3 | 0.0360328 |
| LDHA | lactate dehydrogenase A | 0.035937 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0356514 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0353255 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0345197 |
| SDC4 | syndecan 4 | 0.0343945 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0343934 |
| MSI2 | musashi RNA-binding protein 2 | 0.0343429 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0338143 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0335345 |
| FAM107B | family with sequence similarity 107, member B | 0.0325922 |
| PRELID2 | PRELI domain containing 2 | 0.0319094 |
| DTNA | dystrobrevin, alpha | 0.0318844 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0316141 |
| H1-0 | H1.0 linker histone | 0.0307331 |
| KIAA1217 | KIAA1217 | 0.0299365 |
| ATP10A | ATPase, class V, type 10A | 0.029853 |
| PLIN2 | perilipin 2 | 0.0297162 |
| TNS1 | tensin 1 | 0.0296459 |
| AFDN | afadin, adherens junction formation factor | 0.0295383 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0289862 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0285504 |
| FLNB | filamin B, beta | 0.0284241 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.028187 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0281857 |
| NDRG1 | N-myc downstream regulated 1 | 0.0280936 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0278845 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0277402 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0272442 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0272114 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0270464 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0261767 |
| SLC38A2 | solute carrier family 38, member 2 | 0.026088 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0260613 |
| RNF213 | ring finger protein 213 | 0.0256619 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0255208 |
| CLIC4 | chloride intracellular channel 4 | 0.0248104 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0246594 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0245679 |
| HPCAL1 | hippocalcin-like 1 | 0.0244027 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0242657 |
| CANX | calnexin | 0.0242301 |
| ZNF638 | zinc finger protein 638 | 0.0239771 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0238692 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0236082 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.023534 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0234535 |
| RPS12 | ribosomal protein S12 | 0.0233086 |
| PLXDC2 | plexin domain containing 2 | 0.0232375 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0230735 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0228623 |
| DENND1A | DENN/MADD domain containing 1A | 0.0226653 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0226502 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.022204 |
| MTSS1 | metastasis suppressor 1 | 0.0217624 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0217179 |
| PGK1 | phosphoglycerate kinase 1 | 0.0212247 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0210054 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0209466 |
| USP34 | ubiquitin specific peptidase 34 | 0.0208806 |
| RUNX1 | runt-related transcription factor 1 | 0.0208306 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.473437 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.186239 |
| APOB | apolipoprotein B | -0.119407 |
| C3 | complement component 3 | -0.106205 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.054887 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0527126 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0517894 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0413661 |
| ITGAV | integrin, alpha V | -0.040117 |
| EGR1 | early growth response 1 | -0.0398464 |
| BCL2L1 | BCL2-like 1 | -0.0327111 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.032312 |
| A2M | alpha-2-macroglobulin | -0.0302535 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0293512 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0247526 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0244024 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0226832 |
| MRTFA | myocardin related transcription factor A | -0.0225751 |
| CFB | complement factor B | -0.0225353 |
| ZNF644 | zinc finger protein 644 | -0.0222855 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0213083 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0205555 |
| VCL | vinculin | -0.0203328 |
| RPL34 | ribosomal protein L34 | -0.0198249 |
| ARHGAP9 | Rho GTPase activating protein 9 | -0.0195868 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0195668 |
| FN1 | fibronectin 1 | -0.0195029 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.0191342 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | -0.0189041 |
| PLAC8 | placenta-specific 8 | -0.0184984 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0181579 |
| TXNRD1 | thioredoxin reductase 1 | -0.0181038 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0176657 |
| RPL35A | ribosomal protein L35a | -0.0174451 |
| APOA2 | apolipoprotein A-II | -0.0173802 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0170367 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0168143 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0167523 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0165666 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0160205 |
| RTN4 | reticulon 4 | -0.0153772 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0152954 |
| KIF5B | kinesin family member 5B | -0.0152769 |
| YME1L1 | YME1-like 1 ATPase | -0.0149276 |
| LYZ | lysozyme | -0.0146712 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0144847 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0144349 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0141763 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.014053 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.013943 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0137614 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | -0.0134767 |
| KLHL5 | kelch-like family member 5 | -0.0132528 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0131201 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0131185 |
| SAMD8 | sterile alpha motif domain containing 8 | -0.0130885 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0130073 |
| TPM1 | tropomyosin 1 (alpha) | -0.0122977 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.01218 |
| RPS23 | ribosomal protein S23 | -0.0120569 |
| TRIM26 | tripartite motif containing 26 | -0.0120179 |
| FTL | ferritin, light polypeptide | -0.0119147 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0118217 |
| JMJD1C | jumonji domain containing 1C | -0.011657 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0115698 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0115648 |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl | -0.0115599 |
| IER3 | immediate early response 3 | -0.0115408 |
| GOLGA4 | golgin A4 | -0.0114943 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0112555 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0112288 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0111964 |
| PHF14 | PHD finger protein 14 | -0.0110317 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0110134 |
| TMEM41B | transmembrane protein 41B | -0.0109885 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0108027 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0107919 |
| BPTF | bromodomain PHD finger transcription factor | -0.0107676 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0107442 |
| RRBP1 | ribosome binding protein 1 | -0.0106805 |
| MBTD1 | mbt domain containing 1 | -0.0106308 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0104219 |
| SYNJ2 | synaptojanin 2 | -0.0103251 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0101739 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0100484 |
| CCND1 | cyclin D1 | -0.00997738 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.00996146 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.00989154 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | -0.00983 |
| ZNF486 | zinc finger protein 486 | -0.00976346 |
| SHTN1 | shootin 1 | -0.00969441 |
| NCOA1 | nuclear receptor coactivator 1 | -0.00967337 |
| ICAM1 | intercellular adhesion molecule 1 | -0.00965867 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00965151 |
| LUZP1 | leucine zipper protein 1 | -0.00964081 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.00962864 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00962047 |
| SRPK1 | SRSF protein kinase 1 | -0.00953699 |
| RTKN | rhotekin | -0.00941342 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.00939473 |
