| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clopidogrel perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clopidogrel_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.231927 |
| TXNRD1 | thioredoxin reductase 1 | 0.0853091 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0738577 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0682807 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0682803 |
| ASPH | aspartate beta-hydroxylase | 0.0607265 |
| RPS3 | ribosomal protein S3 | 0.0552027 |
| LMO7 | LIM domain 7 | 0.0525755 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.045184 |
| LDHA | lactate dehydrogenase A | 0.0417443 |
| LAMC2 | laminin, gamma 2 | 0.0409194 |
| SLTM | SAFB-like, transcription modulator | 0.0401352 |
| USP34 | ubiquitin specific peptidase 34 | 0.0391518 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0378634 |
| LAMB3 | laminin, beta 3 | 0.0372944 |
| TES | testin LIM domain protein | 0.0364591 |
| MCL1 | myeloid cell leukemia 1 | 0.0359002 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0354318 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0348161 |
| ANXA2 | annexin A2 | 0.0340146 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0333226 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0321324 |
| PGK1 | phosphoglycerate kinase 1 | 0.0316925 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0313374 |
| PKM | pyruvate kinase, muscle | 0.0308408 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0307716 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0305297 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0305225 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0303386 |
| HDLBP | high density lipoprotein binding protein | 0.0301991 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0299915 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0297818 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0293725 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0292162 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0289721 |
| MKI67 | marker of proliferation Ki-67 | 0.0287741 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0285789 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0283389 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0282173 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0278719 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0275848 |
| TOP1 | topoisomerase (DNA) I | 0.0266739 |
| FAM13A | family with sequence similarity 13, member A | 0.0262252 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0260268 |
| NGLY1 | N-glycanase 1 | 0.0258955 |
| MT2A | metallothionein 2A | 0.0255417 |
| DSPP | dentin sialophosphoprotein | 0.0253865 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0253765 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0251225 |
| CPE | carboxypeptidase E | 0.025096 |
| RPS24 | ribosomal protein S24 | 0.0249451 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0248912 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0246612 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0246597 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0242997 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0240879 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0234161 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0232426 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0232 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0231267 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0228559 |
| SPAG9 | sperm associated antigen 9 | 0.0223458 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0223357 |
| PCBP2 | poly(rC) binding protein 2 | 0.0222172 |
| SEPTIN2 | septin 2 | 0.0221565 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0218864 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0217972 |
| RPS8 | ribosomal protein S8 | 0.0216985 |
| TMSB10 | thymosin beta 10 | 0.0216623 |
| CANX | calnexin | 0.0212431 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0211984 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0209307 |
| RPL37A | ribosomal protein L37a | 0.020886 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0206133 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0205416 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0205134 |
| RSF1 | remodeling and spacing factor 1 | 0.0203238 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0196286 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0194608 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0194541 |
| CTTN | cortactin | 0.0193113 |
| ENSA | endosulfine alpha | 0.0192237 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0190945 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0190079 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0189912 |
| MYOF | myoferlin | 0.0189894 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0189399 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0186025 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0185428 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0183326 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0183267 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0182902 |
| OGA | O-GlcNAcase | 0.0182385 |
| TMF1 | TATA element modulatory factor 1 | 0.0181248 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0181201 |
| ANKRD17 | ankyrin repeat domain 17 | 0.018087 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0179499 |
| SCEL | sciellin | 0.0178685 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0175321 |
| UBC | ubiquitin C | 0.0175199 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.25924 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0367866 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0265263 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0191643 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0174984 |
| EGR1 | early growth response 1 | -0.0131943 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0119273 |
| SEC61G | Sec61 gamma subunit | -0.0116472 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0102466 |
| PDE8A | phosphodiesterase 8A | -0.0101953 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00798174 |
| IFI44L | interferon-induced protein 44-like | -0.00740909 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00706813 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | -0.00696255 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00651786 |
| GRAMD1B | GRAM domain containing 1B | -0.00642647 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.00637901 |
| IER3 | immediate early response 3 | -0.00588854 |
| DTNA | dystrobrevin, alpha | -0.00563343 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00558844 |
| KYNU | kynureninase | -0.00541613 |
| HLA-B | major histocompatibility complex, class I, B | -0.00531989 |
| ASTN2 | astrotactin 2 | -0.00508807 |
| RPS15 | ribosomal protein S15 | -0.00506136 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0048666 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.00476004 |
| CLOCK | clock circadian regulator | -0.00473749 |
| IFI44 | interferon-induced protein 44 | -0.00470072 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00467597 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00451291 |
| PLS1 | plastin 1 | -0.00450743 |
| RPL38 | ribosomal protein L38 | -0.00450269 |
| PER1 | period circadian clock 1 | -0.00441105 |
| FN1 | fibronectin 1 | -0.00429777 |
| H2BC21 | H2B clustered histone 21 | -0.00429153 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00428559 |
| MX1 | MX dynamin-like GTPase 1 | -0.0042848 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0042829 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.00426356 |
| CCND1 | cyclin D1 | -0.00423562 |
| RNF24 | ring finger protein 24 | -0.00413495 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00405578 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.00405157 |
| FOXO3 | forkhead box O3 | -0.0040242 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.00399374 |
| BRD2 | bromodomain containing 2 | -0.00396939 |
| NPTX1 | neuronal pentraxin I | -0.00394578 |
| ATF4 | activating transcription factor 4 | -0.00392897 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00390491 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00387126 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00384486 |
| IGF2 | insulin-like growth factor 2 | -0.00370165 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00368752 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.00367485 |
| VIM | vimentin | -0.00356009 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.0035412 |
| WAC | WW domain containing adaptor with coiled-coil | -0.00352839 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.00340293 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00338474 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00335798 |
| RAB21 | RAB21, member RAS oncogene family | -0.00335178 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | -0.00332343 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00331842 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.00330707 |
| PALLD | palladin, cytoskeletal associated protein | -0.00329715 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.00328766 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00318312 |
| AREG | amphiregulin | -0.00315222 |
| CABIN1 | calcineurin binding protein 1 | -0.00314617 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00314112 |
| RPL21 | ribosomal protein L21 | -0.00313982 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.00313706 |
| KXD1 | KxDL motif containing 1 | -0.0031294 |
| HMGB1 | high mobility group box 1 | -0.00309074 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.00306889 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00303092 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | -0.00301698 |
| WTAP | Wilms tumor 1 associated protein | -0.0030013 |
| GRAMD2B | GRAM domain containing 2B | -0.00296694 |
| COLEC11 | collectin sub-family member 11 | -0.00294439 |
| UBL4A | ubiquitin-like 4A | -0.00292804 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00292779 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00292584 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00290363 |
| PML | promyelocytic leukemia | -0.00288101 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00287493 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00287086 |
| XAF1 | XIAP associated factor 1 | -0.00285761 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.00285754 |
| DGKH | diacylglycerol kinase, eta | -0.00285096 |
| MFSD6 | major facilitator superfamily domain containing 6 | -0.00280839 |
| ARRDC4 | arrestin domain containing 4 | -0.00279199 |
| TRIM28 | tripartite motif containing 28 | -0.00278581 |
| TMC6 | transmembrane channel-like 6 | -0.00273992 |
| SMIM30 | small integral membrane protein 30 | -0.00273551 |
| ADORA2A | adenosine A2a receptor | -0.00273426 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | -0.00273344 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00273087 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.00273068 |
| BCR | breakpoint cluster region | -0.00272912 |
