| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clopidogrel perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clopidogrel_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.131358 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.118108 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.106793 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0828826 |
| TXNRD1 | thioredoxin reductase 1 | 0.0823863 |
| TPM3 | tropomyosin 3 | 0.0817299 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0759066 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0739982 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0655577 |
| RTN4 | reticulon 4 | 0.0632703 |
| RBM25 | RNA binding motif protein 25 | 0.0588731 |
| PARD3 | par-3 family cell polarity regulator | 0.0579056 |
| CCNL1 | cyclin L1 | 0.0564162 |
| WDR43 | WD repeat domain 43 | 0.056416 |
| PCBP2 | poly(rC) binding protein 2 | 0.0539749 |
| ERBIN | erbb2 interacting protein | 0.051298 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0499293 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0495509 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0491864 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0487778 |
| VIM | vimentin | 0.0466217 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0463328 |
| NUP58 | nucleoporin 58 | 0.0459527 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0455332 |
| COPA | coatomer protein complex, subunit alpha | 0.0453937 |
| RBM39 | RNA binding motif protein 39 | 0.0446836 |
| YBX1 | Y box binding protein 1 | 0.0441854 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0426846 |
| TPD52 | tumor protein D52 | 0.0422376 |
| ZNF292 | zinc finger protein 292 | 0.0421527 |
| ZNF207 | zinc finger protein 207 | 0.041417 |
| RPS12 | ribosomal protein S12 | 0.0412738 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0410049 |
| RNF145 | ring finger protein 145 | 0.0409553 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0406516 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0396664 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0396561 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0389827 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0387103 |
| FGB | fibrinogen beta chain | 0.0383446 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0381853 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0377227 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0376176 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370365 |
| USP3 | ubiquitin specific peptidase 3 | 0.0367581 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0363728 |
| ENAH | enabled homolog (Drosophila) | 0.0363721 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0360218 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0356006 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0355842 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0355333 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0354489 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0354398 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0353322 |
| PFN1 | profilin 1 | 0.0351943 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0343939 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0340643 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0340015 |
| PLS3 | plastin 3 | 0.0326174 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0324729 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.032097 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0320824 |
| KIF5B | kinesin family member 5B | 0.032067 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.031222 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0311704 |
| MYOF | myoferlin | 0.0311378 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0309727 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0307378 |
| YBX3 | Y box binding protein 3 | 0.0305122 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0302538 |
| TMEM87A | transmembrane protein 87A | 0.0302234 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0301342 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0299114 |
| ECT2 | epithelial cell transforming 2 | 0.0295078 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0293857 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0293809 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0292426 |
| TPX2 | TPX2, microtubule-associated | 0.0291756 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0291745 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0290775 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0289839 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0288112 |
| MATR3 | matrin 3 | 0.0285722 |
| MORF4L1 | mortality factor 4 like 1 | 0.0285698 |
| CHN1 | chimerin 1 | 0.0283689 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0283634 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0279356 |
| PNN | pinin, desmosome associated protein | 0.0279019 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0276699 |
| RANBP9 | RAN binding protein 9 | 0.0276414 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0273805 |
| NUP153 | nucleoporin 153kDa | 0.0272857 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0271863 |
| FMNL2 | formin-like 2 | 0.0271231 |
| QKI | QKI, KH domain containing, RNA binding | 0.0269412 |
| NCKAP1 | NCK-associated protein 1 | 0.0267357 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0266984 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0266509 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0265115 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0262023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1657 |
| ACTG1 | actin gamma 1 | -0.0923806 |
| IER3 | immediate early response 3 | -0.0862275 |
| IGF2 | insulin-like growth factor 2 | -0.0832603 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0808138 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0704838 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0643961 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0572946 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0546395 |
| CAVIN1 | caveolae associated protein 1 | -0.0437748 |
| MT2A | metallothionein 2A | -0.043366 |
| HLA-B | major histocompatibility complex, class I, B | -0.0422278 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0392754 |
| RPL35A | ribosomal protein L35a | -0.039012 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0374429 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0369932 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0361675 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0324682 |
| RPL34 | ribosomal protein L34 | -0.0316682 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0303934 |
| RPS29 | ribosomal protein S29 | -0.0274715 |
| RPL38 | ribosomal protein L38 | -0.0272539 |
| S100A10 | S100 calcium binding protein A10 | -0.0267046 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0261349 |
| RPS21 | ribosomal protein S21 | -0.025698 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0252784 |
| HLA-E | major histocompatibility complex, class I, E | -0.0249537 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0248757 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0238992 |
| INTS6 | integrator complex subunit 6 | -0.0234355 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0227316 |
| PYGL | phosphorylase, glycogen, liver | -0.0224156 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0216935 |
| AHNAK | AHNAK nucleoprotein | -0.0213027 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0207149 |
| S100A6 | S100 calcium binding protein A6 | -0.0206609 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0205663 |
| SVIL | supervillin | -0.0204651 |
| LMNA | lamin A/C | -0.020023 |
| KYNU | kynureninase | -0.0198884 |
| CDK12 | cyclin-dependent kinase 12 | -0.0198432 |
| RPS15 | ribosomal protein S15 | -0.0191318 |
| RPL11 | ribosomal protein L11 | -0.0189802 |
| CUX1 | cut-like homeobox 1 | -0.0188166 |
| EGFR | epidermal growth factor receptor | -0.0187774 |
| GLIS3 | GLIS family zinc finger 3 | -0.018467 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0183615 |
| CD99 | CD99 molecule | -0.0182282 |
| CMIP | c-Maf inducing protein | -0.0180589 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0179132 |
| MYO1E | myosin IE | -0.017253 |
| HLA-A | major histocompatibility complex, class I, A | -0.0172426 |
| NNMT | nicotinamide N-methyltransferase | -0.0171576 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0170316 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0170228 |
| HMGA2 | high mobility group AT-hook 2 | -0.0170027 |
| RPS8 | ribosomal protein S8 | -0.0169795 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0169264 |
| LOC112694756 | uncharaterized LOC112694756 | -0.016697 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0165316 |
| ATG7 | autophagy related 7 | -0.016485 |
| PCNX4 | pecanex 4 | -0.0163963 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0161968 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0159351 |
| UBB | ubiquitin B | -0.0158236 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0158233 |
| ANGPTL4 | angiopoietin-like 4 | -0.0157137 |
| TNS3 | tensin 3 | -0.0156137 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0154956 |
| GOLGB1 | golgin B1 | -0.0153676 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0153287 |
| HLA-C | major histocompatibility complex, class I, C | -0.0152302 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0149811 |
| PTMA | prothymosin, alpha | -0.0147417 |
| RPL31 | ribosomal protein L31 | -0.014694 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.014642 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0145617 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0145218 |
| RPS23 | ribosomal protein S23 | -0.0143964 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0142752 |
| TPM1 | tropomyosin 1 (alpha) | -0.0140455 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.014035 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0139793 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0139355 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0138258 |
| RPS24 | ribosomal protein S24 | -0.0137413 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0136413 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0136385 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0135281 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0134366 |
| RPLP1 | ribosomal protein, large, P1 | -0.013375 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0133383 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0133337 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0131767 |
| RPS11 | ribosomal protein S11 | -0.0131726 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0131271 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0131003 |
| ASTN2 | astrotactin 2 | -0.0130043 |
| CDK13 | cyclin-dependent kinase 13 | -0.0128761 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0127712 |
