| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clopidogrel perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clopidogrel_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.0772932 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0456274 |
| RAD51B | RAD51 paralog B | 0.0448331 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0419515 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0392557 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0375149 |
| TPM3 | tropomyosin 3 | 0.0314134 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.028785 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0272729 |
| PCBP2 | poly(rC) binding protein 2 | 0.0263453 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0257106 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0242589 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0236019 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0234874 |
| RPS12 | ribosomal protein S12 | 0.0230703 |
| RTN4 | reticulon 4 | 0.0223752 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0223466 |
| OGA | O-GlcNAcase | 0.0218964 |
| RPS3 | ribosomal protein S3 | 0.0216844 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0210482 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0208486 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0207102 |
| GRAMD1B | GRAM domain containing 1B | 0.0206966 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0198947 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0196911 |
| XPO1 | exportin 1 | 0.0192887 |
| MCL1 | myeloid cell leukemia 1 | 0.0189539 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0187651 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0187431 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.018582 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0185788 |
| COPA | coatomer protein complex, subunit alpha | 0.0185014 |
| VIM | vimentin | 0.0184498 |
| RPL37 | ribosomal protein L37 | 0.0182345 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.01761 |
| ZNF638 | zinc finger protein 638 | 0.0172167 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0171422 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0166178 |
| ATP11A | ATPase, class VI, type 11A | 0.0165773 |
| ANO6 | anoctamin 6 | 0.0165349 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0164978 |
| FBXO11 | F-box protein 11 | 0.0164428 |
| RBM25 | RNA binding motif protein 25 | 0.0164329 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0163623 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0162727 |
| ZNF292 | zinc finger protein 292 | 0.0161554 |
| GPHN | gephyrin | 0.0160451 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.015963 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0159235 |
| RPS8 | ribosomal protein S8 | 0.0158745 |
| TMEM41B | transmembrane protein 41B | 0.0156455 |
| PHIP | pleckstrin homology domain interacting protein | 0.0155234 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0154615 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0152433 |
| RPS18 | ribosomal protein S18 | 0.0152361 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0151142 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0150874 |
| CCNL1 | cyclin L1 | 0.0150319 |
| YBX1 | Y box binding protein 1 | 0.0149977 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0149852 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0148947 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0147847 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0144621 |
| PGK1 | phosphoglycerate kinase 1 | 0.0144047 |
| JMJD1C | jumonji domain containing 1C | 0.0143722 |
| BBX | bobby sox homolog (Drosophila) | 0.0140842 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0139784 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0136656 |
| PNN | pinin, desmosome associated protein | 0.0136143 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0135889 |
| RNF145 | ring finger protein 145 | 0.013557 |
| VMP1 | vacuole membrane protein 1 | 0.0135109 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0134886 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0134485 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0134047 |
| USP34 | ubiquitin specific peptidase 34 | 0.0133839 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0133546 |
| SET | SET nuclear proto-oncogene | 0.0132792 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0130991 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.013014 |
| PTK2 | protein tyrosine kinase 2 | 0.0130127 |
| COG5 | component of oligomeric golgi complex 5 | 0.0129435 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0128153 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0127942 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0126247 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0126242 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0125603 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0125287 |
| ATXN2 | ataxin 2 | 0.0125174 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0125031 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0124833 |
| RPL37A | ribosomal protein L37a | 0.0124315 |
| TNPO3 | transportin 3 | 0.0124091 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0124047 |
| R3HDM2 | R3H domain containing 2 | 0.012397 |
| SMYD3 | SET and MYND domain containing 3 | 0.0123203 |
| EXOC4 | exocyst complex component 4 | 0.0123152 |
| PLCB4 | phospholipase C, beta 4 | 0.0121128 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0120993 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0120916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.226316 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0381497 |
| ACTG1 | actin gamma 1 | -0.035302 |
| TMSB10 | thymosin beta 10 | -0.0325628 |
| PTMA | prothymosin, alpha | -0.0324323 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0270826 |
| HLA-B | major histocompatibility complex, class I, B | -0.0238514 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0234268 |
| RPS15 | ribosomal protein S15 | -0.020817 |
| RPS21 | ribosomal protein S21 | -0.0189663 |
| POTEF | POTE ankyrin domain family, member F | -0.01808 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0179712 |
| IGF2 | insulin-like growth factor 2 | -0.0176662 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0153184 |
| DEK | DEK proto-oncogene | -0.014812 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0147172 |
| RPL8 | ribosomal protein L8 | -0.0146886 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0145078 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0143923 |
| RPL34 | ribosomal protein L34 | -0.0139749 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0134168 |
| CCND1 | cyclin D1 | -0.0131599 |
| RPL35A | ribosomal protein L35a | -0.0128778 |
| EGR1 | early growth response 1 | -0.0127481 |
| RPL38 | ribosomal protein L38 | -0.0126062 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0124063 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0123588 |
| TUBB | tubulin, beta class I | -0.0123197 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.011978 |
| FUS | FUS RNA binding protein | -0.0114899 |
| OSMR | oncostatin M receptor | -0.0112994 |
| GNAS | GNAS complex locus | -0.0112372 |
| H1-0 | H1.0 linker histone | -0.0112214 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0110167 |
| RYR3 | ryanodine receptor 3 | -0.0107213 |
| IER3 | immediate early response 3 | -0.0104912 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0103844 |
| TPM2 | tropomyosin 2 (beta) | -0.0102688 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0100915 |
| S100A10 | S100 calcium binding protein A10 | -0.00992952 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0098251 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00982264 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00938563 |
| GOLGB1 | golgin B1 | -0.00930986 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.00928931 |
| KHSRP | KH-type splicing regulatory protein | -0.00913792 |
| HMGA2 | high mobility group AT-hook 2 | -0.00877463 |
| CANX | calnexin | -0.00857104 |
| CAVIN1 | caveolae associated protein 1 | -0.00854322 |
| PDE10A | phosphodiesterase 10A | -0.00827063 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00816357 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -0.00815706 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00794714 |
| VCL | vinculin | -0.00783711 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00780983 |
| TPM4 | tropomyosin 4 | -0.00777875 |
| SRP72 | signal recognition particle 72kDa | -0.0076694 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0076536 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.00762813 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.00755968 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.00754095 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.00744504 |
| JUN | jun proto-oncogene | -0.00741304 |
| DHFR | dihydrofolate reductase | -0.007358 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.00727467 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.00725226 |
| ASTN2 | astrotactin 2 | -0.00715084 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.00713435 |
| NLGN1 | neuroligin 1 | -0.00708777 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0069937 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.00687259 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00682033 |
| STC1 | stanniocalcin 1 | -0.00668463 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00663278 |
| UBB | ubiquitin B | -0.00662238 |
| RPS10 | ribosomal protein S10 | -0.00658142 |
| COL5A2 | collagen, type V, alpha 2 | -0.00655946 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.00652511 |
| HLA-C | major histocompatibility complex, class I, C | -0.00650768 |
| AHNAK | AHNAK nucleoprotein | -0.00648407 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.00646839 |
| RPL11 | ribosomal protein L11 | -0.00642307 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00640199 |
| CD2AP | CD2-associated protein | -0.00627368 |
| ZNF217 | zinc finger protein 217 | -0.00624505 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.00615361 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.00607616 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0060759 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.00604832 |
| BMP5 | bone morphogenetic protein 5 | -0.00590446 |
| RPL32 | ribosomal protein L32 | -0.00588583 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0058151 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00578358 |
| ATN1 | atrophin 1 | -0.0057497 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.00566159 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00564921 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.00564701 |
| BNC2 | basonuclin 2 | -0.00563931 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.005554 |
| CUX1 | cut-like homeobox 1 | -0.005536 |
