| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clopidogrel perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clopidogrel_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0951116 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0911096 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0832263 |
| VIM | vimentin | 0.0831466 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0651269 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0627959 |
| RPS12 | ribosomal protein S12 | 0.0627297 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0621909 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0586727 |
| SPAG9 | sperm associated antigen 9 | 0.0566819 |
| PTMA | prothymosin, alpha | 0.0549655 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.046525 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0444968 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0443618 |
| SMC4 | structural maintenance of chromosomes 4 | 0.042732 |
| MKI67 | marker of proliferation Ki-67 | 0.0425835 |
| RPLP0 | ribosomal protein, large, P0 | 0.0419133 |
| FBXO11 | F-box protein 11 | 0.0409457 |
| SETD5 | SET domain containing 5 | 0.0407951 |
| SRP54 | signal recognition particle 54kDa | 0.0406508 |
| RPL31 | ribosomal protein L31 | 0.0387879 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0385661 |
| YAP1 | Yes-associated protein 1 | 0.0384358 |
| DST | dystonin | 0.0380576 |
| CENPE | centromere protein E, 312kDa | 0.0378068 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0377082 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0364352 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0354186 |
| RTN4 | reticulon 4 | 0.0351436 |
| PCBP2 | poly(rC) binding protein 2 | 0.0348101 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0346749 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0345957 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0343966 |
| YBX1 | Y box binding protein 1 | 0.0338865 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0335302 |
| PFN1 | profilin 1 | 0.0328072 |
| RPS6 | ribosomal protein S6 | 0.0324488 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0323482 |
| RPL23 | ribosomal protein L23 | 0.0322204 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.032157 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0321059 |
| TPX2 | TPX2, microtubule-associated | 0.0317976 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0310723 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0309659 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0308457 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0308214 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.030769 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0307591 |
| CCNA2 | cyclin A2 | 0.0305834 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0304601 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0304488 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.030193 |
| MORF4L2 | mortality factor 4 like 2 | 0.0299258 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0297767 |
| PDGFC | platelet derived growth factor C | 0.0297586 |
| H1-0 | H1.0 linker histone | 0.0297181 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0296285 |
| COPA | coatomer protein complex, subunit alpha | 0.0295821 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0295281 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0293049 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0288952 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0287748 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0287365 |
| ANK2 | ankyrin 2, neuronal | 0.0287123 |
| SGO2 | shugoshin 2 | 0.028595 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0280249 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.02793 |
| TNPO1 | transportin 1 | 0.0275692 |
| RAI1 | retinoic acid induced 1 | 0.0274843 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0271799 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0271113 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0270803 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0270684 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0270469 |
| RPL19 | ribosomal protein L19 | 0.0270189 |
| FIGN | fidgetin | 0.0269962 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0269016 |
| RNF145 | ring finger protein 145 | 0.0267995 |
| RPL12 | ribosomal protein L12 | 0.026685 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0266766 |
| THOC2 | THO complex 2 | 0.026658 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0266575 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0266234 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0266127 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0262544 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0262522 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0262237 |
| RSF1 | remodeling and spacing factor 1 | 0.026202 |
| RPL26 | ribosomal protein L26 | 0.026017 |
| RPL28 | ribosomal protein L28 | 0.0258748 |
| B2M | beta-2-microglobulin | 0.0257414 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0257348 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0257266 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0256008 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0255632 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0255171 |
| NOP58 | NOP58 ribonucleoprotein | 0.0254936 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0252787 |
| TMSB4X | thymosin beta 4, X-linked | 0.0252757 |
| COG5 | component of oligomeric golgi complex 5 | 0.0252146 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.11062 |
| CADM2 | cell adhesion molecule 2 | -0.0786662 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.076484 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0722601 |
| HMCN1 | hemicentin 1 | -0.0573416 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0557362 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0531173 |
| COL1A2 | collagen, type I, alpha 2 | -0.0506241 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0496536 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0456324 |
| PLPP1 | phospholipid phosphatase 1 | -0.0399064 |
| COL3A1 | collagen, type III, alpha 1 | -0.0382762 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0378901 |
| GPC3 | glypican 3 | -0.0378663 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0375821 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0371681 |
| PEG10 | paternally expressed 10 | -0.034419 |
| ACTG1 | actin gamma 1 | -0.0331901 |
| ENAH | enabled homolog (Drosophila) | -0.0327289 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0320574 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0312652 |
| ACTN4 | actinin, alpha 4 | -0.0311835 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0308973 |
| TENM3 | teneurin transmembrane protein 3 | -0.0306154 |
| UPP1 | uridine phosphorylase 1 | -0.0301919 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0301274 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0293739 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0280165 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | -0.0278678 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0278256 |
| ANXA1 | annexin A1 | -0.0275239 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0273754 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0269415 |
| COL5A2 | collagen, type V, alpha 2 | -0.0266175 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.026148 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.025559 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0254851 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0254409 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0253586 |
| AUTS2 | autism susceptibility candidate 2 | -0.0252703 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0252625 |
| ENO1 | enolase 1, (alpha) | -0.0250973 |
| NTM | neurotrimin | -0.0249758 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0249472 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0247685 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0244985 |
| EPHA3 | EPH receptor A3 | -0.0244433 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0242444 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0242166 |
| SYT1 | synaptotagmin I | -0.0239914 |
| CAVIN1 | caveolae associated protein 1 | -0.0236762 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0235889 |
| MYO10 | myosin X | -0.0233065 |
| MAP4 | microtubule-associated protein 4 | -0.0229836 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0226872 |
| TMEM64 | transmembrane protein 64 | -0.0226559 |
| FUS | FUS RNA binding protein | -0.0226039 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0225357 |
| ZNF292 | zinc finger protein 292 | -0.0223452 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0222732 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0222171 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0220925 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0215863 |
| FLNA | filamin A, alpha | -0.0213254 |
| VGLL3 | vestigial-like family member 3 | -0.0212571 |
| THBS1 | thrombospondin 1 | -0.0210984 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0205664 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | -0.020562 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.0201867 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0200997 |
| TFRC | transferrin receptor | -0.0200386 |
| WASF2 | WAS protein family, member 2 | -0.0197295 |
| USP25 | ubiquitin specific peptidase 25 | -0.0195208 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0193193 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | -0.0193084 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0190853 |
| CDK6 | cyclin-dependent kinase 6 | -0.0190724 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0188288 |
| FAM171B | family with sequence similarity 171, member B | -0.0186026 |
| SKI | SKI proto-oncogene | -0.018571 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0184513 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0183559 |
| PCDH11Y | protocadherin 11 Y-linked | -0.0183035 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.0182657 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0182619 |
| NEBL | nebulette | -0.0181333 |
| SLC38A2 | solute carrier family 38, member 2 | -0.018085 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0180818 |
| GANAB | glucosidase, alpha; neutral AB | -0.0180727 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0178611 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0177739 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0176548 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0174719 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.017461 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | -0.0173428 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0172774 |
| YAF2 | YY1 associated factor 2 | -0.0172252 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0169288 |
| MED13L | mediator complex subunit 13-like | -0.0168427 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0167389 |
