| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clotrimazole_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLAT | plasminogen activator, tissue | 0.256211 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.21017 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.19019 |
| B2M | beta-2-microglobulin | 0.130968 |
| DST | dystonin | 0.0825596 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0735575 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0683989 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0677384 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0636065 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0604847 |
| CD44 | CD44 molecule (Indian blood group) | 0.0592392 |
| APP | amyloid beta (A4) precursor protein | 0.0572238 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0561682 |
| ASPH | aspartate beta-hydroxylase | 0.0558554 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0552934 |
| TMSB4X | thymosin beta 4, X-linked | 0.0538059 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0502775 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0479239 |
| HDAC9 | histone deacetylase 9 | 0.0477392 |
| VCL | vinculin | 0.0476581 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0473872 |
| NAV2 | neuron navigator 2 | 0.0473344 |
| PRELID2 | PRELI domain containing 2 | 0.0453779 |
| DOCK5 | dedicator of cytokinesis 5 | 0.045141 |
| LOX | lysyl oxidase | 0.0444458 |
| CENPF | centromere protein F, 350/400kDa | 0.0444113 |
| ANXA2 | annexin A2 | 0.0439208 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0432436 |
| MB21D2 | Mab-21 domain containing 2 | 0.0428391 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0420822 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0420652 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.041841 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0415818 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0403412 |
| COL3A1 | collagen, type III, alpha 1 | 0.0392548 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0386308 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0378342 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0377814 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.036909 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0367767 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0360404 |
| OGA | O-GlcNAcase | 0.0356364 |
| CYTH3 | cytohesin 3 | 0.0356312 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.035221 |
| EZR | ezrin | 0.0348615 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0340955 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0328977 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0327958 |
| MYOF | myoferlin | 0.0325463 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0323308 |
| LDHA | lactate dehydrogenase A | 0.0320157 |
| RAI14 | retinoic acid induced 14 | 0.0319805 |
| SMAD3 | SMAD family member 3 | 0.0318183 |
| ANLN | anillin, actin binding protein | 0.0318098 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0315956 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0315356 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.031036 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0307059 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0307048 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0305513 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0302741 |
| CDH13 | cadherin 13 | 0.0301732 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0299012 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.029825 |
| CEP170 | centrosomal protein 170kDa | 0.029815 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0295739 |
| ERBIN | erbb2 interacting protein | 0.0291621 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0289357 |
| GOLGB1 | golgin B1 | 0.028866 |
| PLEC | plectin | 0.0284637 |
| HLA-B | major histocompatibility complex, class I, B | 0.0284245 |
| DSPP | dentin sialophosphoprotein | 0.0284117 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.028065 |
| JMJD1C | jumonji domain containing 1C | 0.0279862 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0279784 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0279514 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.027674 |
| RASAL2 | RAS protein activator like 2 | 0.0268891 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0268696 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0267658 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0266744 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0266637 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0265455 |
| MKI67 | marker of proliferation Ki-67 | 0.0264576 |
| FLNB | filamin B, beta | 0.0263537 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0262196 |
| SQSTM1 | sequestosome 1 | 0.0261181 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0260324 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0259314 |
| SDC4 | syndecan 4 | 0.0258981 |
| NEK7 | NIMA-related kinase 7 | 0.0258299 |
| PGK1 | phosphoglycerate kinase 1 | 0.0257201 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0256085 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0255723 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.025554 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0254285 |
| MT2A | metallothionein 2A | 0.0253928 |
| OSMR | oncostatin M receptor | 0.0253192 |
| MAP1B | microtubule-associated protein 1B | 0.0252385 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0250164 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.200257 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.167492 |
| VIM | vimentin | -0.0929059 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0685213 |
| S100A6 | S100 calcium binding protein A6 | -0.0559669 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0543699 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0530326 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0491051 |
| COL5A1 | collagen, type V, alpha 1 | -0.0490818 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.048656 |
| NDRG1 | N-myc downstream regulated 1 | -0.0477237 |
| SUCNR1 | succinate receptor 1 | -0.0450764 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0430229 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.039138 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0344647 |
| FN1 | fibronectin 1 | -0.0339765 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0328332 |
| TAGLN2 | transgelin 2 | -0.0325733 |
| CUX1 | cut-like homeobox 1 | -0.0322803 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0319017 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0308049 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0307395 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0297894 |
| INSIG1 | insulin induced gene 1 | -0.0295276 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0294971 |
| MX2 | MX dynamin-like GTPase 2 | -0.0282693 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0275303 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0272427 |
| PTMA | prothymosin, alpha | -0.0272317 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0242146 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0240949 |
| CD109 | CD109 molecule | -0.0240765 |
| TOX | thymocyte selection-associated high mobility group box | -0.0239417 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0234398 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0233757 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0229887 |
| MEIS2 | Meis homeobox 2 | -0.0229034 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0225963 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0225777 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0225043 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0221344 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0212409 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0207214 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0206254 |
| FADS2 | fatty acid desaturase 2 | -0.0206204 |
| GDF15 | growth differentiation factor 15 | -0.0201904 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0201292 |
| TPM1 | tropomyosin 1 (alpha) | -0.0199644 |
| IL7R | interleukin 7 receptor | -0.0199635 |
| POTEF | POTE ankyrin domain family, member F | -0.0196433 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0196274 |
| CD99 | CD99 molecule | -0.0193665 |
| FTL | ferritin, light polypeptide | -0.0191127 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0190744 |
| S100A4 | S100 calcium binding protein A4 | -0.0190587 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0188884 |
| KRT81 | keratin 81, type II | -0.0185321 |
| ACTG1 | actin gamma 1 | -0.0178351 |
| CALR | calreticulin | -0.0178002 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0174884 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0172346 |
| TNS3 | tensin 3 | -0.0169771 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | -0.0169768 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0166153 |
| TPM4 | tropomyosin 4 | -0.0164174 |
| IL32 | interleukin 32 | -0.016238 |
| TAPBP | TAP binding protein (tapasin) | -0.0160287 |
| DCLK2 | doublecortin-like kinase 2 | -0.0158965 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0154628 |
| COL1A1 | collagen, type I, alpha 1 | -0.0152641 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0151193 |
| CD81 | CD81 molecule | -0.015042 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.01491 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0146164 |
| IKBIP | IKBKB interacting protein | -0.0142519 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.014227 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.014013 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0137355 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0137336 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0137304 |
| HSPB1 | heat shock 27kDa protein 1 | -0.013729 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0134521 |
| TGFB1 | transforming growth factor, beta 1 | -0.0133516 |
| LMNA | lamin A/C | -0.0131541 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0128293 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0127427 |
| TTYH3 | tweety family member 3 | -0.0127397 |
| SMIM44 | small integral membrane protein 44 | -0.0126518 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0126061 |
| LRRC17 | leucine rich repeat containing 17 | -0.012522 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.012517 |
| NGLY1 | N-glycanase 1 | -0.0124696 |
| CMIP | c-Maf inducing protein | -0.0123124 |
| VAT1 | vesicle amine transport 1 | -0.0122818 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0122807 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0121864 |
| RPS27L | ribosomal protein S27-like | -0.0120762 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0120581 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.012006 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0119412 |
