| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clotrimazole_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.135066 |
| MT2A | metallothionein 2A | 0.113232 |
| FN1 | fibronectin 1 | 0.0782518 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0690098 |
| VEGFA | vascular endothelial growth factor A | 0.0677512 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0614789 |
| NAV2 | neuron navigator 2 | 0.0549149 |
| B2M | beta-2-microglobulin | 0.0490132 |
| HDAC9 | histone deacetylase 9 | 0.0483765 |
| HMGA2 | high mobility group AT-hook 2 | 0.0483578 |
| SMAD3 | SMAD family member 3 | 0.0478867 |
| CADM1 | cell adhesion molecule 1 | 0.0466238 |
| PLEC | plectin | 0.0434321 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0402887 |
| RASA2 | RAS p21 protein activator 2 | 0.0399408 |
| PRELID2 | PRELI domain containing 2 | 0.0398273 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0390237 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.038338 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0381219 |
| DST | dystonin | 0.0377844 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0370578 |
| FTL | ferritin, light polypeptide | 0.0352804 |
| VMP1 | vacuole membrane protein 1 | 0.0351919 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0349975 |
| RBM39 | RNA binding motif protein 39 | 0.033687 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0327213 |
| QKI | QKI, KH domain containing, RNA binding | 0.0320599 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0319206 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0305715 |
| SPAG9 | sperm associated antigen 9 | 0.0305526 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0297676 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0296751 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.02965 |
| RPS12 | ribosomal protein S12 | 0.0295251 |
| PKM | pyruvate kinase, muscle | 0.0291739 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0289776 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0289057 |
| RPL37A | ribosomal protein L37a | 0.0285588 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0282602 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0279172 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0276342 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.027205 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0271577 |
| TPR | translocated promoter region, nuclear basket protein | 0.0268799 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0267553 |
| SP100 | SP100 nuclear antigen | 0.0265788 |
| RPL31 | ribosomal protein L31 | 0.0265027 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0263281 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0262783 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0260462 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0258723 |
| RIGI | RNA sensor RIG-I | 0.0258483 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0257373 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0257356 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0250918 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0250142 |
| AFAP1 | actin filament associated protein 1 | 0.0249262 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.024654 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.0240894 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0239752 |
| RPS19 | ribosomal protein S19 | 0.0239736 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0238825 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0238429 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0235982 |
| PDE8A | phosphodiesterase 8A | 0.0233807 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0232743 |
| CTBP2 | C-terminal binding protein 2 | 0.0232395 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0230827 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0228693 |
| MYOF | myoferlin | 0.0228374 |
| MED13L | mediator complex subunit 13-like | 0.0228265 |
| RPLP2 | ribosomal protein, large, P2 | 0.0227431 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0226099 |
| MT1X | metallothionein 1X | 0.0224297 |
| SKP1 | S-phase kinase-associated protein 1 | 0.022379 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.021968 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0219505 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0218445 |
| ATXN1 | ataxin 1 | 0.0217242 |
| MSN | moesin | 0.0216695 |
| FBXO32 | F-box protein 32 | 0.0214674 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.021436 |
| ANXA2 | annexin A2 | 0.0213037 |
| MYO1E | myosin IE | 0.0204921 |
| DSPP | dentin sialophosphoprotein | 0.020405 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0202341 |
| RPL12 | ribosomal protein L12 | 0.0200528 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0199125 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0198551 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0198186 |
| NRP2 | neuropilin 2 | 0.0197393 |
| RAI14 | retinoic acid induced 14 | 0.019633 |
| ANXA5 | annexin A5 | 0.0196053 |
| ZNF292 | zinc finger protein 292 | 0.019092 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0190889 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0190718 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0190212 |
| ERBIN | erbb2 interacting protein | 0.0189096 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0187894 |
| OGA | O-GlcNAcase | 0.0187487 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.213562 |
| COL1A2 | collagen, type I, alpha 2 | -0.191897 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.172079 |
| VIM | vimentin | -0.143892 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.138509 |
| NDRG1 | N-myc downstream regulated 1 | -0.107065 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101732 |
| FBN1 | fibrillin 1 | -0.0972494 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0885137 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0832931 |
| STC1 | stanniocalcin 1 | -0.0796354 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0753365 |
| COL5A1 | collagen, type V, alpha 1 | -0.0718671 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0711451 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0586125 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0584126 |
| DPYD | dihydropyrimidine dehydrogenase | -0.057436 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0540302 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0538694 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0531263 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0528731 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0482627 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0474238 |
| CDH13 | cadherin 13 | -0.0471496 |
| TPM4 | tropomyosin 4 | -0.0463013 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0446127 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0429607 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.041505 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0412512 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0407832 |
| CALR | calreticulin | -0.0395556 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0394801 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0384671 |
| PDE10A | phosphodiesterase 10A | -0.037244 |
| CANX | calnexin | -0.0369268 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0355077 |
| S100A6 | S100 calcium binding protein A6 | -0.0351089 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0350662 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0350402 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0349981 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0343444 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.034018 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0328756 |
| IL6 | interleukin 6 | -0.0321314 |
| TAGLN2 | transgelin 2 | -0.0320707 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0305403 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0302054 |
| TMSB10 | thymosin beta 10 | -0.0296055 |
| FOXP1 | forkhead box P1 | -0.0295054 |
| PRKCA | protein kinase C, alpha | -0.0290198 |
| LOX | lysyl oxidase | -0.028882 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0277993 |
| FNDC3B | fibronectin type III domain containing 3B | -0.02746 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0274543 |
| MMP3 | matrix metallopeptidase 3 | -0.0268217 |
| CALU | calumenin | -0.0262399 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0262129 |
| MTDH | metadherin | -0.0261994 |
| CALD1 | caldesmon 1 | -0.026086 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0255659 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0254073 |
| COL5A2 | collagen, type V, alpha 2 | -0.0252873 |
| UST | uronyl-2-sulfotransferase | -0.0245987 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0245698 |
| CA12 | carbonic anhydrase XII | -0.0245212 |
| OSMR | oncostatin M receptor | -0.0244359 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0244226 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0237723 |
| GNAS | GNAS complex locus | -0.0237103 |
| CNTN5 | contactin 5 | -0.0236642 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0234308 |
| TRAM1 | translocation associated membrane protein 1 | -0.0231545 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0226036 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0225577 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0224615 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0224425 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0221296 |
| LMO4 | LIM domain only 4 | -0.0218449 |
| TMEM165 | transmembrane protein 165 | -0.0218219 |
| OXR1 | oxidation resistance 1 | -0.0215301 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.021174 |
| ACTG1 | actin gamma 1 | -0.021164 |
| ANXA1 | annexin A1 | -0.0211509 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0204234 |
| MYADM | myeloid-associated differentiation marker | -0.02036 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0203535 |
| RPL30 | ribosomal protein L30 | -0.020353 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0203204 |
| RUNX1 | runt-related transcription factor 1 | -0.0202962 |
| EFNA5 | ephrin-A5 | -0.0202351 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0197744 |
| TPM1 | tropomyosin 1 (alpha) | -0.0194764 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0194231 |
| COL3A1 | collagen, type III, alpha 1 | -0.0194114 |
| TMEM45A | transmembrane protein 45A | -0.0192177 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0190583 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0189255 |
| GLIS3 | GLIS family zinc finger 3 | -0.0186634 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0186565 |
| PRRX1 | paired related homeobox 1 | -0.0186137 |
