| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clotrimazole_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.26267 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0962634 |
| SVIL | supervillin | 0.0830925 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0811314 |
| DSPP | dentin sialophosphoprotein | 0.080804 |
| ASPH | aspartate beta-hydroxylase | 0.0787862 |
| TNS1 | tensin 1 | 0.0742765 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.071351 |
| EHBP1 | EH domain binding protein 1 | 0.0684313 |
| JMJD1C | jumonji domain containing 1C | 0.0671779 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.064788 |
| NDRG1 | N-myc downstream regulated 1 | 0.0643052 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0626982 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0603307 |
| VEGFA | vascular endothelial growth factor A | 0.0554465 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0541845 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0536815 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0528439 |
| FRMD5 | FERM domain containing 5 | 0.0497323 |
| RPS12 | ribosomal protein S12 | 0.0494545 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0483809 |
| ATP10A | ATPase, class V, type 10A | 0.0483396 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0480518 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0476235 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0463977 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.045877 |
| B2M | beta-2-microglobulin | 0.0458037 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0453316 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0447638 |
| GPC6 | glypican 6 | 0.0445707 |
| DTNA | dystrobrevin, alpha | 0.0440386 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0439295 |
| RUNX1 | runt-related transcription factor 1 | 0.043893 |
| TXNRD1 | thioredoxin reductase 1 | 0.0431575 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0430444 |
| PTK2 | protein tyrosine kinase 2 | 0.0430151 |
| FAM13A | family with sequence similarity 13, member A | 0.0429141 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0398686 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0395615 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0388892 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0384912 |
| GRB10 | growth factor receptor-bound protein 10 | 0.038357 |
| FLNB | filamin B, beta | 0.0356558 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0356051 |
| ZNF292 | zinc finger protein 292 | 0.0351869 |
| RPS6 | ribosomal protein S6 | 0.0351811 |
| RPL14 | ribosomal protein L14 | 0.0349236 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.034577 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0338861 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0338488 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0337779 |
| CCNY | cyclin Y | 0.0337702 |
| RPS17 | ribosomal protein S17 | 0.0323881 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0307529 |
| RBM39 | RNA binding motif protein 39 | 0.0305823 |
| RPL37A | ribosomal protein L37a | 0.0304007 |
| RAD51B | RAD51 paralog B | 0.0301323 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0300259 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0298615 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0297946 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0297544 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0295865 |
| RPS3 | ribosomal protein S3 | 0.0291391 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0291012 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0288847 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0288718 |
| FBXO42 | F-box protein 42 | 0.0286822 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.028213 |
| MT2A | metallothionein 2A | 0.0279766 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0277918 |
| ITGA6 | integrin, alpha 6 | 0.0277897 |
| MCL1 | myeloid cell leukemia 1 | 0.0272668 |
| RPL3 | ribosomal protein L3 | 0.0271321 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0268359 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0266683 |
| CRY1 | cryptochrome circadian clock 1 | 0.0265003 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.026401 |
| AFDN | afadin, adherens junction formation factor | 0.0263579 |
| TPD52 | tumor protein D52 | 0.0262012 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0259638 |
| OPTN | optineurin | 0.025818 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.025808 |
| ARFGEF3 | ARFGEF family member 3 | 0.0254958 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.025384 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0252352 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0250192 |
| GOLGA4 | golgin A4 | 0.0249537 |
| TMEM181 | transmembrane protein 181 | 0.0248288 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0247456 |
| FERMT1 | fermitin family member 1 | 0.0246473 |
| VMP1 | vacuole membrane protein 1 | 0.0246219 |
| FOXP1 | forkhead box P1 | 0.0243223 |
| USP47 | ubiquitin specific peptidase 47 | 0.0240168 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.024001 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0237613 |
| EZR | ezrin | 0.0235443 |
| RLF | rearranged L-myc fusion | 0.0233427 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0233359 |
| OGA | O-GlcNAcase | 0.0231755 |
| RPL5 | ribosomal protein L5 | 0.0231367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.361057 |
| APOB | apolipoprotein B | -0.236114 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.196523 |
| GPC3 | glypican 3 | -0.121124 |
| FN1 | fibronectin 1 | -0.0950593 |
| APOA2 | apolipoprotein A-II | -0.087376 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0825926 |
| AHSG | alpha-2-HS-glycoprotein | -0.0639852 |
| C3 | complement component 3 | -0.0637792 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0617444 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0564289 |
| VCL | vinculin | -0.0559168 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0534071 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0515377 |
| A2M | alpha-2-macroglobulin | -0.051164 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0509461 |
| TRIM26 | tripartite motif containing 26 | -0.050715 |
| HMGA1 | high mobility group AT-hook 1 | -0.0420237 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0416849 |
| LYZ | lysozyme | -0.0408572 |
| ITGAV | integrin, alpha V | -0.0403909 |
| RPLP0 | ribosomal protein, large, P0 | -0.0397116 |
| GNAS | GNAS complex locus | -0.0389372 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0382455 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0381483 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0351001 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336294 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0335175 |
| PTCHD4 | patched domain containing 4 | -0.0329977 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.030944 |
| EGR1 | early growth response 1 | -0.0309171 |
| CFB | complement factor B | -0.0301476 |
| RPS24 | ribosomal protein S24 | -0.0294792 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0294668 |
| CPE | carboxypeptidase E | -0.0286889 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0283706 |
| INTS6 | integrator complex subunit 6 | -0.0281034 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0278546 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0276069 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0274636 |
| PERP | PERP, TP53 apoptosis effector | -0.0269962 |
| FTL | ferritin, light polypeptide | -0.026622 |
| MYO1E | myosin IE | -0.0263132 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.026208 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.026172 |
| UBC | ubiquitin C | -0.0260233 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0259486 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0258331 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0257105 |
| TMEM123 | transmembrane protein 123 | -0.0254186 |
| PLIN2 | perilipin 2 | -0.0249575 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0246604 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0243842 |
| LDHA | lactate dehydrogenase A | -0.0239657 |
| RPL11 | ribosomal protein L11 | -0.0229987 |
| FILIP1L | filamin A interacting protein 1-like | -0.0229494 |
| RPLP1 | ribosomal protein, large, P1 | -0.0228379 |
| CP | ceruloplasmin (ferroxidase) | -0.0216702 |
| PALLD | palladin, cytoskeletal associated protein | -0.0213617 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0209175 |
| GK | glycerol kinase | -0.0208578 |
| GDF15 | growth differentiation factor 15 | -0.0205262 |
| APOE | apolipoprotein E | -0.0203019 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0201614 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0201514 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0200269 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0198579 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0198396 |
| PEG10 | paternally expressed 10 | -0.0197813 |
| RPL35A | ribosomal protein L35a | -0.0197384 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0194037 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.019153 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0191318 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0188351 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0186506 |
| SELENOP | selenoprotein P | -0.0184613 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0183869 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0182924 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0181317 |
| CST3 | cystatin C | -0.0181126 |
| NPR2 | natriuretic peptide receptor 2 | -0.0179975 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0177667 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0176819 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0176782 |
| AGXT | alanine-glyoxylate aminotransferase | -0.017641 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0175433 |
| POTEF | POTE ankyrin domain family, member F | -0.0174473 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0174337 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.017432 |
| KIF21A | kinesin family member 21A | -0.0173715 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0171301 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.017049 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0169789 |
| MATN3 | matrilin 3 | -0.0168107 |
| CTSB | cathepsin B | -0.0167053 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0165561 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0165297 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0164705 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0163014 |
| BPIFB2 | BPI fold containing family B, member 2 | -0.0159472 |
