| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clotrimazole_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.22281 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.220709 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.157228 |
| MTSS1 | metastasis suppressor 1 | 0.136798 |
| LMO7 | LIM domain 7 | 0.130337 |
| SLC35F3 | solute carrier family 35, member F3 | 0.11509 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.105654 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.105232 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0976819 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0883877 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0872801 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0792794 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0784916 |
| RAI14 | retinoic acid induced 14 | 0.0722616 |
| B2M | beta-2-microglobulin | 0.0712014 |
| RASAL2 | RAS protein activator like 2 | 0.0673351 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0643778 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0636698 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0617752 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0615709 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0604599 |
| HMGA2 | high mobility group AT-hook 2 | 0.0601907 |
| EFNA5 | ephrin-A5 | 0.0597954 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0586083 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0584303 |
| CDK6 | cyclin-dependent kinase 6 | 0.0563129 |
| LAMC2 | laminin, gamma 2 | 0.0560083 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0542542 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.053989 |
| INTS6 | integrator complex subunit 6 | 0.0517385 |
| MECOM | MDS1 and EVI1 complex locus | 0.051527 |
| ASPH | aspartate beta-hydroxylase | 0.0498992 |
| PLS3 | plastin 3 | 0.0490728 |
| PTK2 | protein tyrosine kinase 2 | 0.04903 |
| MSN | moesin | 0.0469582 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0453892 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0449418 |
| JMJD1C | jumonji domain containing 1C | 0.0445978 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0444089 |
| UTRN | utrophin | 0.0433273 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0432175 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0425476 |
| HDAC9 | histone deacetylase 9 | 0.0415045 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0412823 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0410448 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.040843 |
| RAD51B | RAD51 paralog B | 0.0407112 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0406587 |
| RNF217 | ring finger protein 217 | 0.0401542 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.039473 |
| DOK5 | docking protein 5 | 0.0393513 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0385365 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0384304 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0381511 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.03782 |
| EGFR | epidermal growth factor receptor | 0.0377666 |
| EXOC4 | exocyst complex component 4 | 0.0371018 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0370427 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0361921 |
| PRSS23 | protease, serine, 23 | 0.0355731 |
| DGKH | diacylglycerol kinase, eta | 0.0353604 |
| IFI44L | interferon-induced protein 44-like | 0.035347 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0351443 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0350266 |
| CALB1 | calbindin 1, 28kDa | 0.0347966 |
| SULF1 | sulfatase 1 | 0.0347756 |
| AMOTL1 | angiomotin like 1 | 0.0347007 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0343031 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.03424 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0330392 |
| SULF2 | sulfatase 2 | 0.0329183 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0325561 |
| DST | dystonin | 0.0313677 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0312609 |
| SMYD3 | SET and MYND domain containing 3 | 0.0310319 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0310157 |
| TMSB4X | thymosin beta 4, X-linked | 0.0308934 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0307618 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0298437 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0297193 |
| NAV2 | neuron navigator 2 | 0.0295081 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0293612 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0293305 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0291036 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0288817 |
| RPL37 | ribosomal protein L37 | 0.0288285 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0288008 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0287649 |
| TGM2 | transglutaminase 2 | 0.0286416 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0285882 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0283466 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0283287 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0282824 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.028187 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0281376 |
| MCL1 | myeloid cell leukemia 1 | 0.0277209 |
| PODXL | podocalyxin-like | 0.0274714 |
| SVIL | supervillin | 0.0274438 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0274035 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0269949 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0710265 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0590493 |
| H1-0 | H1.0 linker histone | -0.0510866 |
| PTMA | prothymosin, alpha | -0.0473694 |
| KRT17 | keratin 17, type I | -0.0472844 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0449592 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0439977 |
| OGA | O-GlcNAcase | -0.0367355 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0358522 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0351212 |
| ANLN | anillin, actin binding protein | -0.0349646 |
| NDRG1 | N-myc downstream regulated 1 | -0.0338359 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0336287 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0332903 |
| TMSB10 | thymosin beta 10 | -0.0323599 |
| EMP1 | epithelial membrane protein 1 | -0.0320209 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0313116 |
| LMNA | lamin A/C | -0.026818 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0260857 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0258614 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0255781 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0254028 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0244964 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.024492 |
| YBX3 | Y box binding protein 3 | -0.0243965 |
| ANKRD33B | ankyrin repeat domain 33B | -0.024318 |
| ANXA2 | annexin A2 | -0.0237846 |
| GOLGA4 | golgin A4 | -0.0234847 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0233788 |
| FSCN1 | fascin actin-bundling protein 1 | -0.02306 |
| RBM39 | RNA binding motif protein 39 | -0.0229434 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0225392 |
| GNAS | GNAS complex locus | -0.022445 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0219573 |
| RLF | rearranged L-myc fusion | -0.021386 |
| SPAG9 | sperm associated antigen 9 | -0.0212703 |
| MORF4L2 | mortality factor 4 like 2 | -0.0211136 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0206246 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0204418 |
| CUL4B | cullin 4B | -0.0198741 |
| AHNAK | AHNAK nucleoprotein | -0.0196003 |
| CAVIN1 | caveolae associated protein 1 | -0.0193105 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0188972 |
| S100A2 | S100 calcium binding protein A2 | -0.018781 |
| CD99 | CD99 molecule | -0.0182995 |
| S100A6 | S100 calcium binding protein A6 | -0.0181827 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0179137 |
| SYPL1 | synaptophysin-like 1 | -0.0178033 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0178029 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0177973 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0177267 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0176338 |
| GATA6 | GATA binding protein 6 | -0.017493 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.017356 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0172732 |
| MT1X | metallothionein 1X | -0.0170515 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0170334 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0169696 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0169343 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0168595 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0167564 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0165229 |
| SRP54 | signal recognition particle 54kDa | -0.0165118 |
| IER3 | immediate early response 3 | -0.0162976 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0162646 |
| S100A4 | S100 calcium binding protein A4 | -0.0162597 |
| STC1 | stanniocalcin 1 | -0.0162336 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0162323 |
| CLU | clusterin | -0.0161282 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0158725 |
| TKT | transketolase | -0.01586 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0156602 |
| S100A10 | S100 calcium binding protein A10 | -0.0155246 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0155156 |
| KIAA1217 | KIAA1217 | -0.0154462 |
| IGF2 | insulin-like growth factor 2 | -0.0152717 |
| NUP58 | nucleoporin 58 | -0.0151477 |
| NRG1 | neuregulin 1 | -0.0151445 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.015119 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0150604 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0148838 |
| KRT14 | keratin 14, type I | -0.0146666 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.014653 |
| TMEM263 | transmembrane protein 263 | -0.0146451 |
| SUCO | SUN domain containing ossification factor | -0.014626 |
| ARRDC3 | arrestin domain containing 3 | -0.0145443 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0143159 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | -0.0142037 |
| CKAP2 | cytoskeleton associated protein 2 | -0.014165 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0141317 |
| HELZ | helicase with zinc finger | -0.0141304 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0141227 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0141041 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0140158 |
| ZNF217 | zinc finger protein 217 | -0.0138296 |
| ARF1 | ADP-ribosylation factor 1 | -0.0138175 |
| DSTN | destrin (actin depolymerizing factor) | -0.0137637 |
| CD47 | CD47 molecule | -0.0137582 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0136227 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0136125 |