| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clotrimazole_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.137218 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.127572 |
| TP63 | tumor protein p63 | 0.126407 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.111831 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.105597 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0855801 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0803445 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0772014 |
| B2M | beta-2-microglobulin | 0.0766697 |
| CAPRIN2 | caprin family member 2 | 0.0751932 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0744529 |
| RPS12 | ribosomal protein S12 | 0.0725353 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0704115 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0680482 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0674284 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0633817 |
| HLA-B | major histocompatibility complex, class I, B | 0.0624726 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0611336 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0604881 |
| VIM | vimentin | 0.0595947 |
| RPL26 | ribosomal protein L26 | 0.0555671 |
| EHBP1 | EH domain binding protein 1 | 0.0554076 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0544954 |
| RPS3 | ribosomal protein S3 | 0.051809 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0479389 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0479058 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0472779 |
| RPL37A | ribosomal protein L37a | 0.045519 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0451769 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0440313 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0415529 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0413825 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0412594 |
| FNIP1 | folliculin interacting protein 1 | 0.0411812 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0411653 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0384184 |
| TMEM41B | transmembrane protein 41B | 0.038401 |
| RPL12 | ribosomal protein L12 | 0.0382501 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0380988 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0380256 |
| TOP1 | topoisomerase (DNA) I | 0.0366499 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0365263 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0363482 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0360678 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0360597 |
| SET | SET nuclear proto-oncogene | 0.0358069 |
| JMJD1C | jumonji domain containing 1C | 0.0345375 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0341331 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0337432 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0336937 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0336205 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0334773 |
| PLK2 | polo-like kinase 2 | 0.0329706 |
| RPL36 | ribosomal protein L36 | 0.0328627 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0326415 |
| RPS17 | ribosomal protein S17 | 0.0322442 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0318423 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0317196 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0315404 |
| SPAG9 | sperm associated antigen 9 | 0.0313399 |
| RPS21 | ribosomal protein S21 | 0.0313289 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0312931 |
| PDCD5 | programmed cell death 5 | 0.0310578 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0309264 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0306104 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0304211 |
| ZNF644 | zinc finger protein 644 | 0.0302501 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0301525 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.030129 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0300613 |
| FMNL2 | formin-like 2 | 0.0298473 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0298025 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0297301 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0295558 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0294988 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0291235 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0290554 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0290162 |
| RPS27A | ribosomal protein S27a | 0.0288674 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0284673 |
| ATF6 | activating transcription factor 6 | 0.028391 |
| CDK6 | cyclin-dependent kinase 6 | 0.0282536 |
| VMP1 | vacuole membrane protein 1 | 0.0281514 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0274978 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0274335 |
| CUL3 | cullin 3 | 0.0273639 |
| TXNRD1 | thioredoxin reductase 1 | 0.027154 |
| GOLGA4 | golgin A4 | 0.0271454 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0268892 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0266419 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0265772 |
| RPS23 | ribosomal protein S23 | 0.0264816 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0261365 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0261329 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0258009 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0257845 |
| RTN4 | reticulon 4 | 0.0255494 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0255423 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0254794 |
| SETX | senataxin | 0.025283 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0904044 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0734109 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0682588 |
| CADM2 | cell adhesion molecule 2 | -0.064904 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0638755 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0623036 |
| RNF213 | ring finger protein 213 | -0.0607813 |
| TNS3 | tensin 3 | -0.0579426 |
| FTL | ferritin, light polypeptide | -0.0572469 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0523262 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0509823 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0477693 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0470868 |
| PGK1 | phosphoglycerate kinase 1 | -0.0451861 |
| ANGPTL4 | angiopoietin-like 4 | -0.0422203 |
| MT1X | metallothionein 1X | -0.039281 |
| NEK10 | NIMA-related kinase 10 | -0.0364679 |
| RPL23 | ribosomal protein L23 | -0.0357356 |
| ZNF217 | zinc finger protein 217 | -0.0357306 |
| RPL35A | ribosomal protein L35a | -0.0350002 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0343921 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.03408 |
| RPLP1 | ribosomal protein, large, P1 | -0.0328354 |
| POTEF | POTE ankyrin domain family, member F | -0.0324364 |
| PFKP | phosphofructokinase, platelet | -0.0313639 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0309915 |
| ACTG1 | actin gamma 1 | -0.0301368 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0298599 |
| LOXL2 | lysyl oxidase-like 2 | -0.0286553 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0286293 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0277313 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0275656 |
| JUN | jun proto-oncogene | -0.0275652 |
| DOCK11 | dedicator of cytokinesis 11 | -0.027022 |
| EMP1 | epithelial membrane protein 1 | -0.0269572 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0268169 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0267478 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0262622 |
| ZNF292 | zinc finger protein 292 | -0.0261854 |
| CANX | calnexin | -0.0256801 |
| HMGB1 | high mobility group box 1 | -0.0253793 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.025273 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0252595 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.025183 |
| CD44 | CD44 molecule (Indian blood group) | -0.0246033 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0245465 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0245209 |
| PKM | pyruvate kinase, muscle | -0.0237651 |
| RAI1 | retinoic acid induced 1 | -0.023742 |
| RAD51B | RAD51 paralog B | -0.0236158 |
| PRELID2 | PRELI domain containing 2 | -0.02358 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0233802 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0231893 |
| RPL5 | ribosomal protein L5 | -0.0228989 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0228349 |
| NDRG1 | N-myc downstream regulated 1 | -0.0227749 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0227208 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0227178 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0225554 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0223962 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0222283 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0221771 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0221728 |
| PYGL | phosphorylase, glycogen, liver | -0.0219543 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0217579 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0215716 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.0212711 |
| VAV2 | vav 2 guanine nucleotide exchange factor | -0.0211577 |
| FAM222B | family with sequence similarity 222, member B | -0.0211428 |
| PRDX1 | peroxiredoxin 1 | -0.02113 |
| RREB1 | ras responsive element binding protein 1 | -0.0209622 |
| MYOF | myoferlin | -0.0207872 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0207174 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0205971 |
| HMGA1 | high mobility group AT-hook 1 | -0.0203764 |
| EGFR | epidermal growth factor receptor | -0.0203417 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0203401 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0200197 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0199817 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0199019 |
| GNAS | GNAS complex locus | -0.0197767 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0197227 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0196239 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0195471 |
| ECE1 | endothelin converting enzyme 1 | -0.0194929 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0192877 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0191858 |
| APOL6 | apolipoprotein L, 6 | -0.0191723 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0191626 |
| RLF | rearranged L-myc fusion | -0.0191279 |
| FOXN3 | forkhead box N3 | -0.018922 |
| PTK2 | protein tyrosine kinase 2 | -0.0188546 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0188426 |
| UBE4B | ubiquitination factor E4B | -0.0187985 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0187447 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0186887 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0185837 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0185015 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0184962 |
| RPL7 | ribosomal protein L7 | -0.0184224 |
