| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clotrimazole_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.173757 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.138511 |
| ASPH | aspartate beta-hydroxylase | 0.125365 |
| TXNRD1 | thioredoxin reductase 1 | 0.117279 |
| GRAMD1B | GRAM domain containing 1B | 0.0787942 |
| LMO7 | LIM domain 7 | 0.0668467 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0659276 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0629477 |
| SCEL | sciellin | 0.0629462 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0609868 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0527183 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0526148 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0525919 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0520633 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0519908 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0519228 |
| TOP1 | topoisomerase (DNA) I | 0.050782 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0506885 |
| MYOF | myoferlin | 0.0441571 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0437089 |
| LAMA4 | laminin, alpha 4 | 0.043694 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0433913 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0418728 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.040402 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0396748 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.039283 |
| DSPP | dentin sialophosphoprotein | 0.0390947 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0384564 |
| RAB10 | RAB10, member RAS oncogene family | 0.0378436 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0374963 |
| ACTG1 | actin gamma 1 | 0.0361244 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0360142 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0354182 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0353937 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0341047 |
| PTK2 | protein tyrosine kinase 2 | 0.0332865 |
| FAM13A | family with sequence similarity 13, member A | 0.0327635 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0314942 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0314673 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0310229 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0302719 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0301262 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0300058 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0299591 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0298171 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0297487 |
| FTL | ferritin, light polypeptide | 0.0296089 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0284935 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.028364 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0280059 |
| USP34 | ubiquitin specific peptidase 34 | 0.0278351 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0277731 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0276716 |
| MCL1 | myeloid cell leukemia 1 | 0.026847 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0266467 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.026622 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.026349 |
| SMAD3 | SMAD family member 3 | 0.0263363 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0262597 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.025863 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0257001 |
| RCOR1 | REST corepressor 1 | 0.0255449 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0252336 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0251196 |
| COPA | coatomer protein complex, subunit alpha | 0.0250723 |
| RIN2 | Ras and Rab interactor 2 | 0.0248972 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0246918 |
| RASA2 | RAS p21 protein activator 2 | 0.0246227 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.024522 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0243781 |
| PCBP2 | poly(rC) binding protein 2 | 0.0243274 |
| SEPTIN2 | septin 2 | 0.0242534 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0241955 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0240861 |
| TMSB10 | thymosin beta 10 | 0.0239962 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0239391 |
| VMP1 | vacuole membrane protein 1 | 0.0237513 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0237482 |
| RAB27B | RAB27B, member RAS oncogene family | 0.023678 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0236226 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0233076 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0233007 |
| FLNB | filamin B, beta | 0.0230852 |
| LAMC2 | laminin, gamma 2 | 0.0229267 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0228524 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0227793 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.022718 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0226827 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0226647 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0226548 |
| ZNF638 | zinc finger protein 638 | 0.0225854 |
| ERBIN | erbb2 interacting protein | 0.0225453 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0224706 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0224054 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0223457 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0223386 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.022256 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0222388 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0221639 |
| PARD3 | par-3 family cell polarity regulator | 0.022093 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101924 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.101605 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0658703 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0615554 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0496441 |
| EGR1 | early growth response 1 | -0.0474549 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0364029 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0360634 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0356056 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0308506 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0300575 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0272729 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0267021 |
| EFNA5 | ephrin-A5 | -0.026099 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0251115 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0247116 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0245624 |
| SP100 | SP100 nuclear antigen | -0.0234493 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0226024 |
| RNF213 | ring finger protein 213 | -0.0221737 |
| NDRG1 | N-myc downstream regulated 1 | -0.0218809 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0208294 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0202864 |
| TRIM56 | tripartite motif containing 56 | -0.0198077 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0196811 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0187423 |
| GM2A | GM2 ganglioside activator | -0.0186684 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.018314 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0181321 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0180991 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0179102 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0176691 |
| RPLP0 | ribosomal protein, large, P0 | -0.0174084 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0168494 |
| IRF1 | interferon regulatory factor 1 | -0.0168237 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0163411 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0159545 |
| HLA-B | major histocompatibility complex, class I, B | -0.0156848 |
| RPS24 | ribosomal protein S24 | -0.0150907 |
| RPL34 | ribosomal protein L34 | -0.0150646 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0147919 |
| AHNAK | AHNAK nucleoprotein | -0.0143109 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0140179 |
| CES1 | carboxylesterase 1 | -0.0139437 |
| NABP1 | nucleic acid binding protein 1 | -0.0139338 |
| PMP22 | peripheral myelin protein 22 | -0.0137875 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0137544 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0136608 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0133025 |
| RIGI | RNA sensor RIG-I | -0.0127667 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0122903 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0118188 |
| ABLIM1 | actin binding LIM protein 1 | -0.0116119 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0113261 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.011299 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0112716 |
| ADAR | adenosine deaminase, RNA-specific | -0.0112682 |
| RPL30 | ribosomal protein L30 | -0.0111571 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0111341 |
| PLSCR1 | phospholipid scramblase 1 | -0.0108261 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0106965 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0105164 |
| MX1 | MX dynamin-like GTPase 1 | -0.0104308 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0103868 |
| ARF1 | ADP-ribosylation factor 1 | -0.010107 |
| KIAA1217 | KIAA1217 | -0.0100802 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0100639 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0100615 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00992865 |
| FAM110C | family with sequence similarity 110, member C | -0.00987957 |
| KRT86 | keratin 86, type II | -0.00971416 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.00967804 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.00956792 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00954397 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.00954193 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.00950609 |
| RPLP1 | ribosomal protein, large, P1 | -0.00938123 |
| SQSTM1 | sequestosome 1 | -0.00933005 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00928539 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.00926038 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00912737 |
| DENND4A | DENN/MADD domain containing 4A | -0.00899638 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.00889968 |
| HLA-E | major histocompatibility complex, class I, E | -0.0088965 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00887238 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.00887136 |
| PLSCR2 | phospholipid scramblase 2 | -0.00866061 |
| ERI2 | ERI1 exoribonuclease family member 2 | -0.0085359 |
| IRF9 | interferon regulatory factor 9 | -0.00836245 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.00833881 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.00824979 |
| JUN | jun proto-oncogene | -0.0081211 |
| UBC | ubiquitin C | -0.00795514 |
| CCNL1 | cyclin L1 | -0.00791624 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | -0.00790676 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.00789071 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00785672 |
| RACK1 | receptor for activated C kinase 1 | -0.00781377 |
| FRY | furry homolog (Drosophila) | -0.00776656 |
| ARRDC3 | arrestin domain containing 3 | -0.00772906 |
