| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clotrimazole_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.256342 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0810532 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.07094 |
| MT2A | metallothionein 2A | 0.0693711 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0653125 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0644 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0626994 |
| RAI14 | retinoic acid induced 14 | 0.0623528 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0605621 |
| FAM20C | family with sequence similarity 20, member C | 0.059737 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0586285 |
| B2M | beta-2-microglobulin | 0.0584356 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.057218 |
| HMGA2 | high mobility group AT-hook 2 | 0.0569211 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0558133 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0557999 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0550673 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0549544 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0539572 |
| NRP1 | neuropilin 1 | 0.0537602 |
| MECOM | MDS1 and EVI1 complex locus | 0.0521832 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0512585 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0504522 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0498425 |
| LOX | lysyl oxidase | 0.0485279 |
| RAD51B | RAD51 paralog B | 0.0466814 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0458748 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0447877 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0441676 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0440381 |
| ETV6 | ets variant 6 | 0.0417379 |
| EFNA5 | ephrin-A5 | 0.0410411 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0405614 |
| MAP1B | microtubule-associated protein 1B | 0.038762 |
| GLCCI1 | glucocorticoid induced 1 | 0.0382842 |
| OSMR | oncostatin M receptor | 0.0378149 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0368107 |
| NTN4 | netrin 4 | 0.036564 |
| ADD3 | adducin 3 (gamma) | 0.0362353 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.0359796 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0359635 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0356221 |
| DST | dystonin | 0.0349087 |
| SIK3 | SIK family kinase 3 | 0.0341425 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0340928 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.033732 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0337216 |
| MT1X | metallothionein 1X | 0.0331291 |
| EGR1 | early growth response 1 | 0.0328812 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0328642 |
| TMSB4X | thymosin beta 4, X-linked | 0.0324419 |
| EHBP1 | EH domain binding protein 1 | 0.0321856 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0310051 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0304187 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0302049 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0285605 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.028403 |
| SYT1 | synaptotagmin I | 0.0282575 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0276873 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0276488 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0276458 |
| JMJD1C | jumonji domain containing 1C | 0.0276304 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0274163 |
| IFI44L | interferon-induced protein 44-like | 0.0269247 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0266533 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0254333 |
| EXOC6B | exocyst complex component 6B | 0.025403 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0250176 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0245478 |
| SP100 | SP100 nuclear antigen | 0.0245221 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0242968 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0242168 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0238492 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.023584 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0235291 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0234495 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0233993 |
| TMSB10 | thymosin beta 10 | 0.0231083 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0229658 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0229115 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0228892 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0228796 |
| ZNF804A | zinc finger protein 804A | 0.0226107 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0225695 |
| RARB | retinoic acid receptor, beta | 0.0224084 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0219949 |
| HLA-B | major histocompatibility complex, class I, B | 0.021956 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0219003 |
| CDK14 | cyclin-dependent kinase 14 | 0.0217909 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0217777 |
| RASAL2 | RAS protein activator like 2 | 0.0217667 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.0217473 |
| ANXA10 | annexin A10 | 0.0216283 |
| ANGPTL4 | angiopoietin-like 4 | 0.0215908 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0213182 |
| RUNX2 | runt-related transcription factor 2 | 0.0211247 |
| TCF12 | transcription factor 12 | 0.0209603 |
| NAV1 | neuron navigator 1 | 0.0209333 |
| RIGI | RNA sensor RIG-I | 0.0208452 |
| HDAC9 | histone deacetylase 9 | 0.0207867 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.240854 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.174476 |
| PCBP2 | poly(rC) binding protein 2 | -0.146696 |
| UBC | ubiquitin C | -0.110857 |
| VIM | vimentin | -0.0951097 |
| CD44 | CD44 molecule (Indian blood group) | -0.0840281 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0784707 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0726824 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0708565 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0661572 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0650921 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0609509 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.060279 |
| PTMA | prothymosin, alpha | -0.0551509 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0536385 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0526569 |
| CALR | calreticulin | -0.0500124 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.048532 |
| ENO1 | enolase 1, (alpha) | -0.0478202 |
| CANX | calnexin | -0.0473574 |
| AHNAK | AHNAK nucleoprotein | -0.0473556 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0471225 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0469536 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0442341 |
| CALU | calumenin | -0.042278 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0384417 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0371546 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0368133 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0343074 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.033659 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0333333 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0328916 |
| ASPH | aspartate beta-hydroxylase | -0.0321339 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0320392 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.031858 |
| APP | amyloid beta (A4) precursor protein | -0.0317177 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0315609 |
| NBAS | neuroblastoma amplified sequence | -0.031231 |
| OGA | O-GlcNAcase | -0.0311277 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0308154 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0305774 |
| HDLBP | high density lipoprotein binding protein | -0.0295876 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0292988 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.028962 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.028702 |
| PKM | pyruvate kinase, muscle | -0.0283836 |
| RPL23 | ribosomal protein L23 | -0.0283419 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0282941 |
| RPS27A | ribosomal protein S27a | -0.0279359 |
| RPL4 | ribosomal protein L4 | -0.0277489 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0277464 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.025868 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0256671 |
| FLNB | filamin B, beta | -0.0251226 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0250112 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0249929 |
| LDHA | lactate dehydrogenase A | -0.0248576 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.02457 |
| RPLP1 | ribosomal protein, large, P1 | -0.0244167 |
| MCL1 | myeloid cell leukemia 1 | -0.0241251 |
| STC1 | stanniocalcin 1 | -0.0231354 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0229068 |
| USP34 | ubiquitin specific peptidase 34 | -0.0227374 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0226855 |
| CDH13 | cadherin 13 | -0.0226418 |
| SPAG9 | sperm associated antigen 9 | -0.0224106 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0218543 |
| YBX1 | Y box binding protein 1 | -0.0218 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0215037 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0213799 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0211515 |
| KIF5B | kinesin family member 5B | -0.0208532 |
| GOLGA4 | golgin A4 | -0.0205113 |
| JUN | jun proto-oncogene | -0.0204368 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0203953 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0202118 |
| POTEF | POTE ankyrin domain family, member F | -0.0198911 |
| RBM39 | RNA binding motif protein 39 | -0.0197668 |
| RPLP0 | ribosomal protein, large, P0 | -0.019513 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0195108 |
| XPO1 | exportin 1 | -0.0192228 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0188806 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0188477 |
| SET | SET nuclear proto-oncogene | -0.018655 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0186533 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0183828 |
| FBN1 | fibrillin 1 | -0.018225 |
| TXNRD1 | thioredoxin reductase 1 | -0.0180504 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0176701 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.017628 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0176157 |
| CD109 | CD109 molecule | -0.0175301 |
| PTEN | phosphatase and tensin homolog | -0.0174975 |
| COPA | coatomer protein complex, subunit alpha | -0.0174189 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0172157 |
| MYO6 | myosin VI | -0.0171251 |
| TMEM263 | transmembrane protein 263 | -0.0170384 |
| FLNA | filamin A, alpha | -0.0167728 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.0166676 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0166053 |
