| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clotrimazole_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.275979 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.177785 |
| KYNU | kynureninase | 0.0745621 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0729277 |
| RPS12 | ribosomal protein S12 | 0.0729263 |
| FTL | ferritin, light polypeptide | 0.0683988 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0659556 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0633921 |
| MT2A | metallothionein 2A | 0.0555646 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0536483 |
| PDLIM5 | PDZ and LIM domain 5 | 0.052159 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0498971 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0492034 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0484489 |
| WWOX | WW domain containing oxidoreductase | 0.0469378 |
| RPS21 | ribosomal protein S21 | 0.0467073 |
| RPS8 | ribosomal protein S8 | 0.0458328 |
| RPL37A | ribosomal protein L37a | 0.0426598 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0403571 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0383585 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0380457 |
| RPL31 | ribosomal protein L31 | 0.0375586 |
| NTN4 | netrin 4 | 0.0372071 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0370127 |
| RPL23 | ribosomal protein L23 | 0.0355626 |
| INTS6 | integrator complex subunit 6 | 0.0355063 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0354717 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0353693 |
| RPS3 | ribosomal protein S3 | 0.034719 |
| RPS17 | ribosomal protein S17 | 0.0346885 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0339655 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0336265 |
| B2M | beta-2-microglobulin | 0.0335322 |
| RPL36 | ribosomal protein L36 | 0.0332768 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0328742 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0319139 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0319096 |
| NRG1 | neuregulin 1 | 0.0312033 |
| TMSB10 | thymosin beta 10 | 0.0308316 |
| EXOC6B | exocyst complex component 6B | 0.0304981 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0303272 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0293917 |
| RPS23 | ribosomal protein S23 | 0.0290998 |
| SCFD1 | sec1 family domain containing 1 | 0.0288804 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0288078 |
| USP34 | ubiquitin specific peptidase 34 | 0.028756 |
| COG5 | component of oligomeric golgi complex 5 | 0.0286615 |
| BMP6 | bone morphogenetic protein 6 | 0.0284336 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0282183 |
| NEGR1 | neuronal growth regulator 1 | 0.0281148 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0278808 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0278582 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0276598 |
| FAM107B | family with sequence similarity 107, member B | 0.0276151 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.027503 |
| VEGFC | vascular endothelial growth factor C | 0.0272897 |
| ASPH | aspartate beta-hydroxylase | 0.0272862 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0270414 |
| CCDC88A | coiled-coil domain containing 88A | 0.0266225 |
| ZNF644 | zinc finger protein 644 | 0.0265569 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0263715 |
| RPL12 | ribosomal protein L12 | 0.0261777 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0257841 |
| RPL36A | ribosomal protein L36a | 0.0254374 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0253425 |
| RPL9 | ribosomal protein L9 | 0.025065 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0250045 |
| EPGN | epithelial mitogen | 0.0244473 |
| MYOF | myoferlin | 0.0242429 |
| RPL14 | ribosomal protein L14 | 0.0242334 |
| PSEN1 | presenilin 1 | 0.0240303 |
| PRR16 | proline rich 16 | 0.0238051 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0235878 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0234504 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.023208 |
| USP47 | ubiquitin specific peptidase 47 | 0.0229556 |
| RSPO3 | R-spondin 3 | 0.0228683 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0226792 |
| GOLGB1 | golgin B1 | 0.0226713 |
| SMYD3 | SET and MYND domain containing 3 | 0.0226155 |
| BRD2 | bromodomain containing 2 | 0.0226026 |
| TBCA | tubulin folding cofactor A | 0.0224117 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0222973 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.022224 |
| RPS14 | ribosomal protein S14 | 0.0220538 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0220326 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.022004 |
| COPA | coatomer protein complex, subunit alpha | 0.0219811 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0219577 |
| PFN1 | profilin 1 | 0.0218637 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0218052 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0217183 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0214673 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0209691 |
| RPLP2 | ribosomal protein, large, P2 | 0.020846 |
| RPL28 | ribosomal protein L28 | 0.0207955 |
| ZNF146 | zinc finger protein 146 | 0.0206249 |
| FHIT | fragile histidine triad | 0.0206205 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0204223 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0203868 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.246294 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172499 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156113 |
| AHNAK | AHNAK nucleoprotein | -0.127632 |
| IGF2 | insulin-like growth factor 2 | -0.111491 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109941 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.104992 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.102203 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0798246 |
| VIM | vimentin | -0.079221 |
| ACTG1 | actin gamma 1 | -0.0786592 |
| PYGL | phosphorylase, glycogen, liver | -0.0781307 |
| CAVIN1 | caveolae associated protein 1 | -0.0734149 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0725726 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0676503 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0615403 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0574667 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0562621 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0554409 |
| LDHA | lactate dehydrogenase A | -0.0535986 |
| SVIL | supervillin | -0.0535705 |
| ANXA2 | annexin A2 | -0.053302 |
| PTMA | prothymosin, alpha | -0.0527219 |
| TPM4 | tropomyosin 4 | -0.0526741 |
| EGR1 | early growth response 1 | -0.0518924 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0494746 |
| TXNRD1 | thioredoxin reductase 1 | -0.0489294 |
| LOC112694756 | uncharaterized LOC112694756 | -0.046832 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0467953 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0460151 |
| FLNB | filamin B, beta | -0.0452403 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0444653 |
| IER3 | immediate early response 3 | -0.043741 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0431686 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0431596 |
| POTEF | POTE ankyrin domain family, member F | -0.0430576 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0413874 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0410779 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0386735 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0386674 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0386665 |
| RPL4 | ribosomal protein L4 | -0.0384958 |
| APP | amyloid beta (A4) precursor protein | -0.0384386 |
| PFKP | phosphofructokinase, platelet | -0.0372319 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0365148 |
| THBS1 | thrombospondin 1 | -0.0364777 |
| PKM | pyruvate kinase, muscle | -0.0360849 |
| SQSTM1 | sequestosome 1 | -0.0351977 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0351617 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0345538 |
| CANX | calnexin | -0.0340625 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0335059 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0334809 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0333956 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0332669 |
| KIF5B | kinesin family member 5B | -0.0332294 |
| GNAS | GNAS complex locus | -0.0328845 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0327253 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.032675 |
| DENND5B | DENN/MADD domain containing 5B | -0.0320448 |
| HDAC9 | histone deacetylase 9 | -0.0319314 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.031691 |
| ARF1 | ADP-ribosylation factor 1 | -0.0315854 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0314121 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0314048 |
| HLA-E | major histocompatibility complex, class I, E | -0.0310634 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.030591 |
| DST | dystonin | -0.0300033 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.029944 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0298511 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.029824 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0297728 |
| JUN | jun proto-oncogene | -0.0293656 |
| S100A6 | S100 calcium binding protein A6 | -0.0293266 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0289564 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0284577 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0284396 |
| ANXA1 | annexin A1 | -0.0284217 |
| S100A10 | S100 calcium binding protein A10 | -0.0283046 |
| MATR3 | matrin 3 | -0.0281808 |
| TPD52 | tumor protein D52 | -0.0279908 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0277364 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0276747 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0273978 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0267157 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.026269 |
| CALU | calumenin | -0.0261636 |
| LAMC2 | laminin, gamma 2 | -0.0255872 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.025064 |
| H1-0 | H1.0 linker histone | -0.0250595 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0244507 |
| RBM39 | RNA binding motif protein 39 | -0.0244151 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0240177 |
| TAGLN2 | transgelin 2 | -0.023956 |
| ACTN1 | actinin, alpha 1 | -0.0236697 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0233346 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0232184 |
| PHF20 | PHD finger protein 20 | -0.0231893 |
| SMAD3 | SMAD family member 3 | -0.0227033 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0226617 |
