| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clotrimazole_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.23627 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.180789 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.126036 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0822489 |
| RAD51B | RAD51 paralog B | 0.0819709 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0791058 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0759986 |
| MCL1 | myeloid cell leukemia 1 | 0.0690513 |
| TPM3 | tropomyosin 3 | 0.0674003 |
| FMNL2 | formin-like 2 | 0.066551 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0648779 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0617187 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0580521 |
| TXNRD1 | thioredoxin reductase 1 | 0.0544169 |
| DST | dystonin | 0.0540247 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0535295 |
| EXOC4 | exocyst complex component 4 | 0.0468858 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0467243 |
| PRKCE | protein kinase C, epsilon | 0.0461883 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0461085 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0450837 |
| PRELID2 | PRELI domain containing 2 | 0.0440017 |
| RPS12 | ribosomal protein S12 | 0.0427778 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.042644 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0418688 |
| WWOX | WW domain containing oxidoreductase | 0.0405785 |
| ATXN1 | ataxin 1 | 0.0391035 |
| RPS3 | ribosomal protein S3 | 0.0387039 |
| ATP11A | ATPase, class VI, type 11A | 0.0375239 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0364118 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.036334 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0358313 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0355807 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0353719 |
| TPM2 | tropomyosin 2 (beta) | 0.0352612 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.035205 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0343755 |
| RPS17 | ribosomal protein S17 | 0.0340507 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0339143 |
| AEBP2 | AE binding protein 2 | 0.0333684 |
| HOMER1 | homer scaffolding protein 1 | 0.0332297 |
| RPS2 | ribosomal protein S2 | 0.0329621 |
| BRD2 | bromodomain containing 2 | 0.0324987 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0310222 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0309276 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0308346 |
| FBXO11 | F-box protein 11 | 0.0305034 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0303984 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0302209 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0299309 |
| VMP1 | vacuole membrane protein 1 | 0.0299195 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0293085 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0289123 |
| SVIL | supervillin | 0.0282315 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0280979 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0272341 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0271538 |
| INTS6 | integrator complex subunit 6 | 0.0270159 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0261737 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0261044 |
| YAP1 | Yes-associated protein 1 | 0.0258759 |
| NRG1 | neuregulin 1 | 0.0253254 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0251928 |
| GRAMD1B | GRAM domain containing 1B | 0.0248611 |
| PCBP2 | poly(rC) binding protein 2 | 0.0248578 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0247656 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0247059 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0245604 |
| RPS8 | ribosomal protein S8 | 0.024321 |
| RPS10 | ribosomal protein S10 | 0.0241801 |
| CMIP | c-Maf inducing protein | 0.0235357 |
| CAPRIN2 | caprin family member 2 | 0.0233364 |
| HDAC4 | histone deacetylase 4 | 0.0231136 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0226368 |
| RPL3 | ribosomal protein L3 | 0.022491 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0224359 |
| SBF2 | SET binding factor 2 | 0.0223758 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0223488 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.022263 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0222615 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0222537 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0221543 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0218987 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0218944 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0218317 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0217472 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0216995 |
| CUX1 | cut-like homeobox 1 | 0.0214622 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0213587 |
| NRDC | nardilysin convertase | 0.0213104 |
| YBX1 | Y box binding protein 1 | 0.0211915 |
| SET | SET nuclear proto-oncogene | 0.0210377 |
| GOLGB1 | golgin B1 | 0.0210106 |
| BMERB1 | bMERB domain containing 1 | 0.0205682 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.020272 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0202284 |
| MYO10 | myosin X | 0.0201861 |
| SMAD3 | SMAD family member 3 | 0.0200636 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0197747 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0197672 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.066604 |
| PTMA | prothymosin, alpha | -0.0611059 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0492369 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0460719 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.042525 |
| RPL35A | ribosomal protein L35a | -0.042457 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0418753 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0413356 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0407735 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0407075 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0384716 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0377032 |
| MKI67 | marker of proliferation Ki-67 | -0.0367539 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0355503 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.034129 |
| IGF2 | insulin-like growth factor 2 | -0.0335292 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0331819 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0331245 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0329589 |
| GNAS | GNAS complex locus | -0.0319073 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0306945 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0305156 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0303741 |
| DEK | DEK proto-oncogene | -0.0303657 |
| H3-3B | H3.3 histone B | -0.0298565 |
| OSMR | oncostatin M receptor | -0.0289721 |
| SGO2 | shugoshin 2 | -0.0285468 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.027637 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0273638 |
| TPI1 | triosephosphate isomerase 1 | -0.0273245 |
| TUBA1C | tubulin, alpha 1c | -0.0270812 |
| EGR1 | early growth response 1 | -0.0270538 |
| PHIP | pleckstrin homology domain interacting protein | -0.0265305 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0265055 |
| MIS18BP1 | MIS18 binding protein 1 | -0.026415 |
| ACTG1 | actin gamma 1 | -0.025895 |
| TPX2 | TPX2, microtubule-associated | -0.0257694 |
| TPM4 | tropomyosin 4 | -0.0256219 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0248472 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0247522 |
| VIM | vimentin | -0.0244565 |
| RPL11 | ribosomal protein L11 | -0.0244073 |
| CAVIN1 | caveolae associated protein 1 | -0.0240885 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0238027 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0234506 |
| HLA-B | major histocompatibility complex, class I, B | -0.0233799 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0224926 |
| SRP72 | signal recognition particle 72kDa | -0.0224671 |
| CENPF | centromere protein F, 350/400kDa | -0.0223417 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0220735 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0217409 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.021587 |
| RPLP0 | ribosomal protein, large, P0 | -0.0214389 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0212796 |
| ZFR | zinc finger RNA binding protein | -0.0212294 |
| H1-0 | H1.0 linker histone | -0.0208533 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0208171 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0206606 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.020494 |
| VCL | vinculin | -0.0200957 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0199272 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0196841 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0194751 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0194493 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0194448 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0193015 |
| S100A6 | S100 calcium binding protein A6 | -0.0192894 |
| UBB | ubiquitin B | -0.019208 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0190868 |
| THOC2 | THO complex 2 | -0.0189951 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0189138 |
| HMGA1 | high mobility group AT-hook 1 | -0.018885 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0186867 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0183695 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0183531 |
| PRR11 | proline rich 11 | -0.01834 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0182451 |
| FNBP4 | formin binding protein 4 | -0.0181861 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0181671 |
| NOP58 | NOP58 ribonucleoprotein | -0.0180425 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0180169 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0179098 |
| TMEM165 | transmembrane protein 165 | -0.0178471 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0178022 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0177248 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0177197 |
| R3HDM1 | R3H domain containing 1 | -0.0174174 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0173518 |
| BSG | basigin (Ok blood group) | -0.0173285 |
| LMNA | lamin A/C | -0.0172279 |
| KIF2C | kinesin family member 2C | -0.0172078 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0170199 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0168991 |
| NABP1 | nucleic acid binding protein 1 | -0.0167299 |
| IMMT | inner membrane protein, mitochondrial | -0.0165397 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0164866 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0164852 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0164023 |
| RBM25 | RNA binding motif protein 25 | -0.0163193 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0162477 |
