| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clotrimazole_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.135961 |
| FTL | ferritin, light polypeptide | 0.128335 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0878005 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0872558 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.08593 |
| G0S2 | G0/G1 switch 2 | 0.0807622 |
| TSC22D2 | TSC22 domain family, member 2 | 0.079902 |
| DSPP | dentin sialophosphoprotein | 0.0793097 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.077958 |
| MT2A | metallothionein 2A | 0.0770704 |
| LAMB3 | laminin, beta 3 | 0.075366 |
| DTNA | dystrobrevin, alpha | 0.064404 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.062355 |
| EZR | ezrin | 0.0614304 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0610384 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0588854 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0577619 |
| ERBIN | erbb2 interacting protein | 0.0550692 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0539267 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0539248 |
| RBM25 | RNA binding motif protein 25 | 0.0513877 |
| LAMC2 | laminin, gamma 2 | 0.0513038 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.050414 |
| RASA2 | RAS p21 protein activator 2 | 0.0491551 |
| SDC4 | syndecan 4 | 0.0480926 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0474145 |
| MSN | moesin | 0.0473838 |
| RNF145 | ring finger protein 145 | 0.0458401 |
| UPP1 | uridine phosphorylase 1 | 0.0457531 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.045606 |
| MYO6 | myosin VI | 0.0445834 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0440361 |
| SLMAP | sarcolemma associated protein | 0.0439807 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0432625 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0416475 |
| RPS12 | ribosomal protein S12 | 0.0413053 |
| RPL14 | ribosomal protein L14 | 0.0412873 |
| RPS3 | ribosomal protein S3 | 0.0411349 |
| MYO5B | myosin VB | 0.0406552 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0401942 |
| FNBP1L | formin binding protein 1-like | 0.0400477 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0400316 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0397615 |
| TOP1 | topoisomerase (DNA) I | 0.0394869 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0388925 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0387561 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0380588 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.036704 |
| MEF2A | myocyte enhancer factor 2A | 0.0361144 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0360227 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0356215 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0354442 |
| FHIT | fragile histidine triad | 0.0344994 |
| MYO10 | myosin X | 0.0330307 |
| FLNB | filamin B, beta | 0.0326523 |
| TJP2 | tight junction protein 2 | 0.0326024 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0324504 |
| MAP1B | microtubule-associated protein 1B | 0.0323291 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0323105 |
| DST | dystonin | 0.0320581 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0312933 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0312641 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0310537 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0307765 |
| ZNF292 | zinc finger protein 292 | 0.0305802 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0305663 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0304033 |
| GPX4 | glutathione peroxidase 4 | 0.0303583 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0303397 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.029991 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0295252 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0293441 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0292741 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0291843 |
| PCBP2 | poly(rC) binding protein 2 | 0.0286621 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.028409 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.028344 |
| B2M | beta-2-microglobulin | 0.0283068 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0282031 |
| PLEC | plectin | 0.0280577 |
| HMGA1 | high mobility group AT-hook 1 | 0.0279001 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0275456 |
| FAM13A | family with sequence similarity 13, member A | 0.0272342 |
| RYBP | RING1 and YY1 binding protein | 0.0268904 |
| FOSL1 | FOS-like antigen 1 | 0.0267 |
| ANXA5 | annexin A5 | 0.0266831 |
| OPTN | optineurin | 0.0264672 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0263212 |
| QKI | QKI, KH domain containing, RNA binding | 0.0260089 |
| FMNL2 | formin-like 2 | 0.0260033 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0258208 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0254978 |
| CD46 | CD46 molecule, complement regulatory protein | 0.025374 |
| JUP | junction plakoglobin | 0.0251188 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0249599 |
| RBM39 | RNA binding motif protein 39 | 0.0246755 |
| DUSP10 | dual specificity phosphatase 10 | 0.0245946 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0241649 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0240336 |
| YBX3 | Y box binding protein 3 | 0.023864 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.268411 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.136274 |
| PTMA | prothymosin, alpha | -0.120311 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0979645 |
| TMSB10 | thymosin beta 10 | -0.0885844 |
| POTEF | POTE ankyrin domain family, member F | -0.0863043 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0800812 |
| S100A6 | S100 calcium binding protein A6 | -0.0798297 |
| RPL35A | ribosomal protein L35a | -0.0705965 |
| ACTG1 | actin gamma 1 | -0.0702163 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0684043 |
| EFNA5 | ephrin-A5 | -0.067221 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0667774 |
| GNAS | GNAS complex locus | -0.0654667 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0602632 |
| LDHA | lactate dehydrogenase A | -0.0573565 |
| VCL | vinculin | -0.0564855 |
| TPM4 | tropomyosin 4 | -0.0552326 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0509365 |
| FBXO32 | F-box protein 32 | -0.0504711 |
| CCND1 | cyclin D1 | -0.0494271 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0490977 |
| ARF1 | ADP-ribosylation factor 1 | -0.0484846 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0480332 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0477995 |
| UBC | ubiquitin C | -0.0468082 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0461226 |
| GOLGA4 | golgin A4 | -0.0453456 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0450665 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0439846 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0436322 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.043403 |
| EPCAM | epithelial cell adhesion molecule | -0.0408319 |
| RPLP0 | ribosomal protein, large, P0 | -0.0401394 |
| KRT7 | keratin 7, type II | -0.0400617 |
| TPI1 | triosephosphate isomerase 1 | -0.0400295 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0395505 |
| RPS24 | ribosomal protein S24 | -0.038733 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0383912 |
| CTSB | cathepsin B | -0.0374415 |
| FNIP1 | folliculin interacting protein 1 | -0.03673 |
| FBXO34 | F-box protein 34 | -0.0362624 |
| CALU | calumenin | -0.0354273 |
| PALLD | palladin, cytoskeletal associated protein | -0.0349539 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0341539 |
| TMEM263 | transmembrane protein 263 | -0.0339221 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0337406 |
| TKT | transketolase | -0.0334248 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0329772 |
| UBAP1 | ubiquitin associated protein 1 | -0.0329402 |
| HDLBP | high density lipoprotein binding protein | -0.0328567 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0327631 |
| HLA-E | major histocompatibility complex, class I, E | -0.0325056 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0321042 |
| KRT18 | keratin 18, type I | -0.0320775 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0319636 |
| RPS25 | ribosomal protein S25 | -0.0311173 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.031009 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0306251 |
| MYO1E | myosin IE | -0.0306075 |
| RPLP1 | ribosomal protein, large, P1 | -0.0302159 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0298035 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0298032 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.029678 |
| CANX | calnexin | -0.0296568 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0295069 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.029263 |
| NF1 | neurofibromin 1 | -0.0291236 |
| MCU | mitochondrial calcium uniporter | -0.0287714 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.028345 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0280733 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0279087 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0279059 |
| RNF213 | ring finger protein 213 | -0.0278887 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0274551 |
| CTSD | cathepsin D | -0.0272658 |
| ASPH | aspartate beta-hydroxylase | -0.0272556 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0271555 |
| MX2 | MX dynamin-like GTPase 2 | -0.027031 |
| ZNF217 | zinc finger protein 217 | -0.027008 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0269073 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0268768 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0268574 |
| ARF4 | ADP-ribosylation factor 4 | -0.0268526 |
| YY1 | YY1 transcription factor | -0.0264375 |
| CD109 | CD109 molecule | -0.0262209 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0261113 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.025658 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0253506 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0251923 |
| CEP350 | centrosomal protein 350kDa | -0.0250478 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.024958 |
| RPL11 | ribosomal protein L11 | -0.0248058 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0247618 |
| OCLN | occludin | -0.0244678 |
| CLTC | clathrin, heavy chain (Hc) | -0.0243619 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0243318 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0242002 |
| ANXA2 | annexin A2 | -0.0240667 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0240163 |
