| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clotrimazole_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.146773 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.100652 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0965722 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0964112 |
| SMAD3 | SMAD family member 3 | 0.0854469 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0828366 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0819943 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0722392 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0689188 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0664761 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0648707 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.063166 |
| STC1 | stanniocalcin 1 | 0.0629132 |
| VCL | vinculin | 0.0618875 |
| PRKCA | protein kinase C, alpha | 0.0615221 |
| ZNF638 | zinc finger protein 638 | 0.0608113 |
| VIM | vimentin | 0.0597794 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0595663 |
| RBM39 | RNA binding motif protein 39 | 0.0592051 |
| MYOF | myoferlin | 0.0591346 |
| KIF16B | kinesin family member 16B | 0.0576262 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0563684 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0556645 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0555143 |
| PDE10A | phosphodiesterase 10A | 0.0552782 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0548814 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0541292 |
| HMGA2 | high mobility group AT-hook 2 | 0.0536256 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0533783 |
| ASPH | aspartate beta-hydroxylase | 0.0533522 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0527091 |
| MED13L | mediator complex subunit 13-like | 0.0518964 |
| FAM107B | family with sequence similarity 107, member B | 0.051866 |
| DST | dystonin | 0.0511401 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0508501 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0507312 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0504434 |
| RUNX1 | runt-related transcription factor 1 | 0.0502439 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.049587 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0493746 |
| B2M | beta-2-microglobulin | 0.049306 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0492322 |
| RPS19 | ribosomal protein S19 | 0.0485699 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0480971 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0477257 |
| SHTN1 | shootin 1 | 0.0468185 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0463924 |
| GLG1 | golgi glycoprotein 1 | 0.0462212 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0462031 |
| GPC6 | glypican 6 | 0.0444908 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0440721 |
| MSN | moesin | 0.0437756 |
| RIGI | RNA sensor RIG-I | 0.043345 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0432829 |
| ZNF207 | zinc finger protein 207 | 0.043229 |
| EHBP1 | EH domain binding protein 1 | 0.0423239 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0417959 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0416649 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0413023 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0412559 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0411349 |
| NAV2 | neuron navigator 2 | 0.0410706 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.039926 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0394981 |
| AFDN | afadin, adherens junction formation factor | 0.0388618 |
| MCL1 | myeloid cell leukemia 1 | 0.038512 |
| CUX1 | cut-like homeobox 1 | 0.0375743 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.037284 |
| ATXN1 | ataxin 1 | 0.036119 |
| NF1 | neurofibromin 1 | 0.0358576 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0355277 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0355232 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0350973 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0348004 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0347385 |
| NPAS2 | neuronal PAS domain protein 2 | 0.034712 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0340791 |
| JMJD1C | jumonji domain containing 1C | 0.0337419 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.033121 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0329253 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0326338 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0325765 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0322059 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0321604 |
| TPM1 | tropomyosin 1 (alpha) | 0.0317107 |
| SETD2 | SET domain containing 2 | 0.0306558 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0306083 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0304998 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0301575 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0299431 |
| MYO1E | myosin IE | 0.0297449 |
| RNF213 | ring finger protein 213 | 0.0297037 |
| CRY1 | cryptochrome circadian clock 1 | 0.0296078 |
| PCBP2 | poly(rC) binding protein 2 | 0.0295898 |
| NPTN | neuroplastin | 0.0294449 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0292076 |
| DENND5B | DENN/MADD domain containing 5B | 0.0291428 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0289854 |
| GOLGB1 | golgin B1 | 0.0289197 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0286245 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102354 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0899045 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0596098 |
| CANX | calnexin | -0.0594409 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0557842 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0555382 |
| DSTN | destrin (actin depolymerizing factor) | -0.0555234 |
| CD2AP | CD2-associated protein | -0.0553272 |
| MATR3 | matrin 3 | -0.0536971 |
| RPL7 | ribosomal protein L7 | -0.0515622 |
| FAM20C | family with sequence similarity 20, member C | -0.0492111 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0491325 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0490824 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0485478 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0485463 |
| CDK13 | cyclin-dependent kinase 13 | -0.048244 |
| CDCP1 | CUB domain containing protein 1 | -0.0481856 |
| FTL | ferritin, light polypeptide | -0.0476751 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0456969 |
| NEBL | nebulette | -0.0453268 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0451186 |
| POTEF | POTE ankyrin domain family, member F | -0.045068 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0450303 |
| VMP1 | vacuole membrane protein 1 | -0.0449614 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0444366 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0444037 |
| YBX1 | Y box binding protein 1 | -0.0441868 |
| ARRDC3 | arrestin domain containing 3 | -0.0439337 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0432785 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0426783 |
| FAT1 | FAT atypical cadherin 1 | -0.0424913 |
| TPR | translocated promoter region, nuclear basket protein | -0.042311 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0422554 |
| PFN1 | profilin 1 | -0.0418095 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0416207 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0414981 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0413811 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0412292 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0412091 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0409005 |
| TENM3 | teneurin transmembrane protein 3 | -0.0407596 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0407413 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0398583 |
| MYO6 | myosin VI | -0.0393918 |
| RHOA | ras homolog family member A | -0.0389518 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0388816 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0388101 |
| COG5 | component of oligomeric golgi complex 5 | -0.03858 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0384728 |
| YBX3 | Y box binding protein 3 | -0.0383032 |
| RPL12 | ribosomal protein L12 | -0.0375238 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0374321 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0374097 |
| RBMX | RNA binding motif protein, X-linked | -0.03727 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0372623 |
| ENO1 | enolase 1, (alpha) | -0.0371017 |
| RPL32 | ribosomal protein L32 | -0.0368508 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0365665 |
| HLA-A | major histocompatibility complex, class I, A | -0.0365078 |
| RPL19 | ribosomal protein L19 | -0.0364772 |
| WDR70 | WD repeat domain 70 | -0.0362884 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0360223 |
| KRT18 | keratin 18, type I | -0.0359289 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0359094 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0358229 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0357008 |
| RORA | RAR-related orphan receptor A | -0.0355612 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0355582 |
| COL5A2 | collagen, type V, alpha 2 | -0.035549 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0353568 |
| RPLP0 | ribosomal protein, large, P0 | -0.0352065 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0348607 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0347213 |
| IPO7 | importin 7 | -0.0344048 |
| HELZ | helicase with zinc finger | -0.034118 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0340521 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0337736 |
| CNKSR3 | CNKSR family member 3 | -0.0331785 |
| PDE8A | phosphodiesterase 8A | -0.0328715 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.032636 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0324337 |
| TLK1 | tousled-like kinase 1 | -0.0322916 |
| MAP4 | microtubule-associated protein 4 | -0.0321523 |
| FOXO3 | forkhead box O3 | -0.0319957 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0319817 |
| MYO1D | myosin ID | -0.0319212 |
| RNF149 | ring finger protein 149 | -0.031706 |
| FAM13A | family with sequence similarity 13, member A | -0.0312849 |
| YEATS2 | YEATS domain containing 2 | -0.0312739 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0310301 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0309066 |
| IER3 | immediate early response 3 | -0.0307537 |
| LSAMP | limbic system-associated membrane protein | -0.0307411 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0305624 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0304814 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0300594 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0299758 |
| QKI | QKI, KH domain containing, RNA binding | -0.0294741 |
| EGFR | epidermal growth factor receptor | -0.029198 |
| COL1A2 | collagen, type I, alpha 2 | -0.0290903 |
