| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clotrimazole_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.105853 |
| NTM | neurotrimin | 0.0933183 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0868425 |
| DST | dystonin | 0.0852116 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0825612 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0790155 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0708393 |
| RPS12 | ribosomal protein S12 | 0.0619504 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0591314 |
| USP25 | ubiquitin specific peptidase 25 | 0.0519259 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0504189 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.049661 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0485944 |
| JMJD1C | jumonji domain containing 1C | 0.0479553 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0472585 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0467474 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0467064 |
| TJP1 | tight junction protein 1 | 0.0443347 |
| FOXP2 | forkhead box P2 | 0.0438172 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0436736 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0433062 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0430809 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0427478 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0417282 |
| ANK2 | ankyrin 2, neuronal | 0.0411874 |
| MEF2A | myocyte enhancer factor 2A | 0.0406847 |
| NFIA | nuclear factor I/A | 0.0399548 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.038382 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.037078 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0368533 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0359923 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0355987 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0355817 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.034648 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0343973 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0335672 |
| EFNA5 | ephrin-A5 | 0.0331715 |
| GOLGA4 | golgin A4 | 0.0330417 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0325739 |
| ZNF608 | zinc finger protein 608 | 0.03224 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0321838 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0320421 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0317761 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0314585 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0306834 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0306206 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0300828 |
| COL5A2 | collagen, type V, alpha 2 | 0.0296615 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0293085 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.029029 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0289048 |
| FIGN | fidgetin | 0.0285888 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0284867 |
| RBM25 | RNA binding motif protein 25 | 0.0280946 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0279426 |
| NFIB | nuclear factor I/B | 0.0279028 |
| YAP1 | Yes-associated protein 1 | 0.0278706 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0278057 |
| UTRN | utrophin | 0.027548 |
| RTTN | rotatin | 0.0273983 |
| CDH19 | cadherin 19, type 2 | 0.0273972 |
| BRD2 | bromodomain containing 2 | 0.0272495 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0272191 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0268407 |
| PCDH18 | protocadherin 18 | 0.026795 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0266971 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0266966 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0266957 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0265025 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0264797 |
| MT2A | metallothionein 2A | 0.0262374 |
| RREB1 | ras responsive element binding protein 1 | 0.0259958 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.025969 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0258033 |
| ASPH | aspartate beta-hydroxylase | 0.0254834 |
| RYBP | RING1 and YY1 binding protein | 0.0253627 |
| SRPK2 | SRSF protein kinase 2 | 0.0253452 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0252525 |
| BNC2 | basonuclin 2 | 0.0249534 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0246214 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0246145 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0245498 |
| SET | SET nuclear proto-oncogene | 0.024521 |
| WAC | WW domain containing adaptor with coiled-coil | 0.024455 |
| TPM3 | tropomyosin 3 | 0.0241648 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0241616 |
| RPL36 | ribosomal protein L36 | 0.024026 |
| NCKAP1 | NCK-associated protein 1 | 0.0237304 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0236402 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0235446 |
| RPS2 | ribosomal protein S2 | 0.0234734 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0234653 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0233302 |
| ZNF638 | zinc finger protein 638 | 0.023297 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0232412 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0232291 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.022912 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0228731 |
| NUMB | numb homolog (Drosophila) | 0.0228136 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0226853 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.193889 |
| GPC3 | glypican 3 | -0.150047 |
| COL3A1 | collagen, type III, alpha 1 | -0.141336 |
| VIM | vimentin | -0.13887 |
| COL1A2 | collagen, type I, alpha 2 | -0.123366 |
| COL11A1 | collagen, type XI, alpha 1 | -0.113638 |
| PTMA | prothymosin, alpha | -0.109791 |
| GNAS | GNAS complex locus | -0.0874125 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0710853 |
| PGK1 | phosphoglycerate kinase 1 | -0.0699915 |
| PEG10 | paternally expressed 10 | -0.0685572 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0629273 |
| RPS16 | ribosomal protein S16 | -0.0625186 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0558607 |
| H1-0 | H1.0 linker histone | -0.0529299 |
| RPL35A | ribosomal protein L35a | -0.0525291 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0520914 |
| ACTG1 | actin gamma 1 | -0.0504989 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.049707 |
| PCDH9 | protocadherin 9 | -0.0489575 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0487273 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0458137 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0458113 |
| SNX6 | sorting nexin 6 | -0.0457066 |
| CAVIN1 | caveolae associated protein 1 | -0.0456091 |
| TENM3 | teneurin transmembrane protein 3 | -0.0425 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0422221 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0414786 |
| CALU | calumenin | -0.0407004 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0403519 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0401532 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0397706 |
| RPLP0 | ribosomal protein, large, P0 | -0.0391131 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0390979 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0388951 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0385705 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0385085 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0379682 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0372748 |
| EMP1 | epithelial membrane protein 1 | -0.0371443 |
| CADM2 | cell adhesion molecule 2 | -0.0358866 |
| ZNF385D | zinc finger protein 385D | -0.0352169 |
| SAMD11 | sterile alpha motif domain containing 11 | -0.0348511 |
| RAI1 | retinoic acid induced 1 | -0.0345695 |
| GSE1 | Gse1 coiled-coil protein | -0.0341925 |
| SFTPA2 | surfactant protein A2 | -0.0341377 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0334174 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0333014 |
| MED12L | mediator complex subunit 12-like | -0.0332515 |
| RPS8 | ribosomal protein S8 | -0.0330858 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0327077 |
| ITGAV | integrin, alpha V | -0.0327025 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0325158 |
| UPP1 | uridine phosphorylase 1 | -0.0325031 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0321719 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0315527 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0315348 |
| HMCN1 | hemicentin 1 | -0.0312932 |
| PCDH7 | protocadherin 7 | -0.0308833 |
| KLHL5 | kelch-like family member 5 | -0.0305997 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305448 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0304775 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0291916 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0291798 |
| KIF4A | kinesin family member 4A | -0.0283302 |
| FST | follistatin | -0.0281727 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0280777 |
| PRPF6 | pre-mRNA processing factor 6 | -0.0279312 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0277533 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0270006 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0267879 |
| MKI67 | marker of proliferation Ki-67 | -0.0265971 |
| RPN2 | ribophorin II | -0.0265931 |
| ENO1 | enolase 1, (alpha) | -0.0264132 |
| S100A10 | S100 calcium binding protein A10 | -0.0264069 |
| SQSTM1 | sequestosome 1 | -0.0258414 |
| MAP4 | microtubule-associated protein 4 | -0.0255177 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0255142 |
| CENPF | centromere protein F, 350/400kDa | -0.0254771 |
| AHNAK | AHNAK nucleoprotein | -0.0253103 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0252996 |
| GABARAP | GABA(A) receptor-associated protein | -0.0251982 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0250223 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0250194 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0249326 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | -0.0246815 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0246106 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0245908 |
| SMYD3 | SET and MYND domain containing 3 | -0.0242716 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0242658 |
| SPAG9 | sperm associated antigen 9 | -0.0242453 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0240931 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0239482 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0239104 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0238882 |
| APOE | apolipoprotein E | -0.0236772 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0236715 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0235565 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0235492 |
| ARF1 | ADP-ribosylation factor 1 | -0.0234808 |
