| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Clotrimazole_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.0933917 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0889067 |
| GPC6 | glypican 6 | 0.0799163 |
| B2M | beta-2-microglobulin | 0.0710669 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.068141 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0606491 |
| RPS12 | ribosomal protein S12 | 0.0597343 |
| RPL14 | ribosomal protein L14 | 0.0523946 |
| HDAC9 | histone deacetylase 9 | 0.0523869 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0510149 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0502059 |
| EHBP1 | EH domain binding protein 1 | 0.0495917 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0493967 |
| ATXN1 | ataxin 1 | 0.0468884 |
| AHNAK | AHNAK nucleoprotein | 0.0437045 |
| OGA | O-GlcNAcase | 0.0421314 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0413565 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0388463 |
| VCAN | versican | 0.0387508 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0386015 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0375523 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0374149 |
| GLIS3 | GLIS family zinc finger 3 | 0.0360558 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0352134 |
| VCL | vinculin | 0.0349849 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0338291 |
| WFDC10B | WAP four-disulfide core domain 10B | 0.0329319 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0328853 |
| GOLGB1 | golgin B1 | 0.0314229 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0310271 |
| BICC1 | BicC family RNA binding protein 1 | 0.030706 |
| RPS17 | ribosomal protein S17 | 0.0305303 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0305292 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0301817 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0297471 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0297128 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0294631 |
| SMAD3 | SMAD family member 3 | 0.0288305 |
| ASPH | aspartate beta-hydroxylase | 0.0285295 |
| CD2AP | CD2-associated protein | 0.027888 |
| CEP250 | centrosomal protein 250kDa | 0.0276419 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0272544 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0261721 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0251806 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0246093 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0242717 |
| PCBP3 | poly(rC) binding protein 3 | 0.0232899 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0232652 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0232467 |
| MT1X | metallothionein 1X | 0.0231211 |
| SDC4 | syndecan 4 | 0.0230213 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.022962 |
| FHIT | fragile histidine triad | 0.0228217 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0222461 |
| EXT1 | exostosin glycosyltransferase 1 | 0.022144 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0219665 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0219015 |
| THBS2 | thrombospondin 2 | 0.0218678 |
| ANGPTL4 | angiopoietin-like 4 | 0.0216547 |
| HDAC8 | histone deacetylase 8 | 0.0214779 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.021367 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0213368 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0207588 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0207272 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.020713 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0206966 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0205077 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0203993 |
| EZR | ezrin | 0.0200488 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0197662 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0197595 |
| TMEM132D | transmembrane protein 132D | 0.0196856 |
| ATM | ATM serine/threonine kinase | 0.0195838 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0195543 |
| PHF3 | PHD finger protein 3 | 0.0194053 |
| EGFR | epidermal growth factor receptor | 0.0193733 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0192947 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0191878 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0189764 |
| ERBIN | erbb2 interacting protein | 0.0187155 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0187041 |
| RPL12 | ribosomal protein L12 | 0.0186463 |
| FMNL2 | formin-like 2 | 0.0185497 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0185345 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0184978 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0184785 |
| ADORA2B | adenosine A2b receptor | 0.0183938 |
| ZNF644 | zinc finger protein 644 | 0.018285 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0182603 |
| SETX | senataxin | 0.0182467 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0179983 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0178758 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0177545 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.017427 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0173452 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0173245 |
| RPS3 | ribosomal protein S3 | 0.0172913 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0172421 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0170178 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0169503 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.180195 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.170492 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.14063 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.12831 |
| PTMA | prothymosin, alpha | -0.0960602 |
| FN1 | fibronectin 1 | -0.0951986 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0919382 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0867602 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0853708 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0853315 |
| FRMD4A | FERM domain containing 4A | -0.0790988 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0755404 |
| CD44 | CD44 molecule (Indian blood group) | -0.0709697 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0682818 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0678886 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0672662 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0638054 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0610859 |
| FNDC3B | fibronectin type III domain containing 3B | -0.061084 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.060428 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.057633 |
| RPS6 | ribosomal protein S6 | -0.0572916 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0544177 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0535866 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0527777 |
| PDE10A | phosphodiesterase 10A | -0.0511049 |
| KYNU | kynureninase | -0.0509408 |
| STC1 | stanniocalcin 1 | -0.0508537 |
| TPM4 | tropomyosin 4 | -0.0505959 |
| C3 | complement component 3 | -0.0490919 |
| CDH13 | cadherin 13 | -0.0490635 |
| HLA-B | major histocompatibility complex, class I, B | -0.0481304 |
| SLC38A1 | solute carrier family 38, member 1 | -0.047587 |
| NDRG1 | N-myc downstream regulated 1 | -0.047155 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0465863 |
| POTEF | POTE ankyrin domain family, member F | -0.0462603 |
| PKM | pyruvate kinase, muscle | -0.0457256 |
| SFTPA2 | surfactant protein A2 | -0.0455282 |
| TPM1 | tropomyosin 1 (alpha) | -0.045444 |
| HLA-E | major histocompatibility complex, class I, E | -0.0453681 |
| PCBP2 | poly(rC) binding protein 2 | -0.0447437 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0446637 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0441926 |
| RPLP1 | ribosomal protein, large, P1 | -0.0422334 |
| ADM | adrenomedullin | -0.0421894 |
| RPL35A | ribosomal protein L35a | -0.0419202 |
| PLIN2 | perilipin 2 | -0.0416404 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0411757 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.040737 |
| HMGA1 | high mobility group AT-hook 1 | -0.0405787 |
| FTL | ferritin, light polypeptide | -0.0404513 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0397918 |
| SPAG9 | sperm associated antigen 9 | -0.0397164 |
| CENPF | centromere protein F, 350/400kDa | -0.0388416 |
| CALR | calreticulin | -0.0388407 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0387398 |
| GNAS | GNAS complex locus | -0.0387281 |
| COL1A2 | collagen, type I, alpha 2 | -0.0380409 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0372902 |
| ANLN | anillin, actin binding protein | -0.0372627 |
| RPL7 | ribosomal protein L7 | -0.0364937 |
| VEGFA | vascular endothelial growth factor A | -0.0362732 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0362708 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0356621 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0356351 |
| MSN | moesin | -0.0352713 |
| TXNIP | thioredoxin interacting protein | -0.0352591 |
| TPX2 | TPX2, microtubule-associated | -0.0347367 |
| MKI67 | marker of proliferation Ki-67 | -0.0346776 |
| CCNL1 | cyclin L1 | -0.0343675 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0342912 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0340471 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0337887 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0336939 |
| CADM1 | cell adhesion molecule 1 | -0.0331017 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0328578 |
| TAGLN2 | transgelin 2 | -0.0322259 |
| TKT | transketolase | -0.0321799 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0320085 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0318773 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.031794 |
| RPS23 | ribosomal protein S23 | -0.0317655 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0316357 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0315287 |
| CTSB | cathepsin B | -0.0311475 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0311167 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0307945 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0307808 |
| MATR3 | matrin 3 | -0.0307415 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0306778 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0305965 |
| CTSD | cathepsin D | -0.0302645 |
| CLMP | CXADR-like membrane protein | -0.0302141 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0301666 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0300496 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.029849 |
| COL1A1 | collagen, type I, alpha 1 | -0.0298385 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.029834 |
| MAP4 | microtubule-associated protein 4 | -0.0298287 |
| RPL39 | ribosomal protein L39 | -0.0297692 |