| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Clotrimazole perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Clotrimazole_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.114268 |
| VIM | vimentin | 0.095175 |
| CDH13 | cadherin 13 | 0.0915864 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0839241 |
| EGFR | epidermal growth factor receptor | 0.0827958 |
| NRXN3 | neurexin 3 | 0.0819436 |
| ASPH | aspartate beta-hydroxylase | 0.0782297 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0781854 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0770777 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.070909 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.065291 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0600559 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0598794 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0562818 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0562418 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0546461 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.051942 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0518134 |
| STC1 | stanniocalcin 1 | 0.0515324 |
| HMGA2 | high mobility group AT-hook 2 | 0.0512236 |
| TMSB10 | thymosin beta 10 | 0.0507965 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0493924 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0489046 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0474077 |
| SDC4 | syndecan 4 | 0.0458717 |
| GLIS3 | GLIS family zinc finger 3 | 0.0455146 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.044135 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.043715 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0430427 |
| RAI14 | retinoic acid induced 14 | 0.0414383 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0414194 |
| INTS6 | integrator complex subunit 6 | 0.0409175 |
| VMP1 | vacuole membrane protein 1 | 0.0406429 |
| RND3 | Rho family GTPase 3 | 0.039486 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0394267 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0390724 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0386452 |
| EHBP1 | EH domain binding protein 1 | 0.0384245 |
| ANXA2 | annexin A2 | 0.0383569 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0382796 |
| USP34 | ubiquitin specific peptidase 34 | 0.0374369 |
| GOLGB1 | golgin B1 | 0.0370059 |
| FAM13A | family with sequence similarity 13, member A | 0.036926 |
| EXOC4 | exocyst complex component 4 | 0.0363024 |
| RPS19 | ribosomal protein S19 | 0.0359964 |
| ERBIN | erbb2 interacting protein | 0.0357948 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0357295 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0356692 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0356163 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0355419 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.034937 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0344728 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0344036 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0342358 |
| MYO10 | myosin X | 0.0341666 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0339743 |
| FRMD4A | FERM domain containing 4A | 0.0331537 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0331032 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0330473 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0325627 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0323102 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0317019 |
| OSMR | oncostatin M receptor | 0.0316958 |
| UBE3C | ubiquitin protein ligase E3C | 0.0312999 |
| CUL3 | cullin 3 | 0.0312091 |
| ZNF207 | zinc finger protein 207 | 0.0310718 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.030892 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0307249 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0307128 |
| SON | SON DNA binding protein | 0.0303649 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0302079 |
| SQSTM1 | sequestosome 1 | 0.0294334 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0292455 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0291717 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0288507 |
| ANTXR2 | anthrax toxin receptor 2 | 0.028833 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0287395 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.0284345 |
| ATXN1 | ataxin 1 | 0.0283898 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0282789 |
| PCM1 | pericentriolar material 1 | 0.0282666 |
| SPAG9 | sperm associated antigen 9 | 0.0281547 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0280333 |
| VEGFC | vascular endothelial growth factor C | 0.0278524 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0278081 |
| MYO9A | myosin IXA | 0.0277861 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0276518 |
| IGF2 | insulin-like growth factor 2 | 0.0276421 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0275899 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0274805 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0273278 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0273067 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0272858 |
| VCL | vinculin | 0.0271915 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0271629 |
| RPS17 | ribosomal protein S17 | 0.0271361 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0270654 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0267631 |
| PTK2 | protein tyrosine kinase 2 | 0.0267042 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0266281 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.140293 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0971188 |
| FN1 | fibronectin 1 | -0.0933023 |
| COL1A1 | collagen, type I, alpha 1 | -0.0897325 |
| MT2A | metallothionein 2A | -0.0808266 |
| MAP1B | microtubule-associated protein 1B | -0.0644514 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0634222 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0611066 |
| POTEF | POTE ankyrin domain family, member F | -0.0553658 |
| COL1A2 | collagen, type I, alpha 2 | -0.0526937 |
| PTMA | prothymosin, alpha | -0.0514551 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0512021 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0511631 |
| ACTG1 | actin gamma 1 | -0.0503637 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0489448 |
| PKM | pyruvate kinase, muscle | -0.0475406 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0439584 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0438252 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.043505 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0424726 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0421158 |
| PTN | pleiotrophin | -0.0416273 |
| H3-3B | H3.3 histone B | -0.0410245 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0405695 |
| EGR1 | early growth response 1 | -0.0404568 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0399458 |
| CALR | calreticulin | -0.0398202 |
| LDHA | lactate dehydrogenase A | -0.0382174 |
| MKI67 | marker of proliferation Ki-67 | -0.0377767 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0376507 |
| HMGB1 | high mobility group box 1 | -0.0352588 |
| ZNF395 | zinc finger protein 395 | -0.0349378 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0346852 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0344436 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0337223 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | -0.0334871 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0328958 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.03274 |
| BSG | basigin (Ok blood group) | -0.0325556 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.031899 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0313542 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0308367 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0301862 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0300728 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.030055 |
| FAM13B | family with sequence similarity 13, member B | -0.0297808 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0295085 |
| CCNI | cyclin I | -0.0294362 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0291458 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.0290608 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0289644 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0289548 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0286486 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0280619 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0279988 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.027907 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.027736 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0276159 |
| FNBP1 | formin binding protein 1 | -0.0272808 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0270546 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0268575 |
| PHF21A | PHD finger protein 21A | -0.026838 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0267245 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0267203 |
| VGLL4 | vestigial-like family member 4 | -0.0263898 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0263004 |
| TFG | TRK-fused gene | -0.0262923 |
| CALU | calumenin | -0.026266 |
| SEPTIN7 | septin 7 | -0.0259177 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0257108 |
| HMGB2 | high mobility group box 2 | -0.0251778 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0249195 |
| RPL9 | ribosomal protein L9 | -0.0248442 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0244863 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0243725 |
| TANK | TRAF family member-associated NFKB activator | -0.0243 |
| USP33 | ubiquitin specific peptidase 33 | -0.0242678 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0242287 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0241225 |
| XPO1 | exportin 1 | -0.0240014 |
| RPL28 | ribosomal protein L28 | -0.0239381 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0238149 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0237584 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0236884 |
| NRBP1 | nuclear receptor binding protein 1 | -0.0236161 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0235543 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0235154 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0230687 |
| PTMS | parathymosin | -0.0230225 |
| ANLN | anillin, actin binding protein | -0.0228829 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0228285 |
| KIF5B | kinesin family member 5B | -0.0227352 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0227019 |
| TPX2 | TPX2, microtubule-associated | -0.0225492 |
| GGNBP2 | gametogenetin binding protein 2 | -0.022421 |
| TMEM123 | transmembrane protein 123 | -0.0222845 |
| WDR45B | WD repeat domain 45B | -0.0222656 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0222411 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0220942 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.0220381 |
