| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.190968 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.176993 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.166386 |
| AHNAK | AHNAK nucleoprotein | 0.137893 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.120164 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.118492 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.109055 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.105468 |
| CANX | calnexin | 0.102636 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0979264 |
| DST | dystonin | 0.08238 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0816202 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0696471 |
| TPM4 | tropomyosin 4 | 0.068314 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0651098 |
| LOXL2 | lysyl oxidase-like 2 | 0.0646124 |
| FNIP1 | folliculin interacting protein 1 | 0.0626324 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0622604 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0607659 |
| PODXL | podocalyxin-like | 0.0606773 |
| NAV2 | neuron navigator 2 | 0.0605598 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0582101 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.057359 |
| GOLGA4 | golgin A4 | 0.0547445 |
| CDH13 | cadherin 13 | 0.054138 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0533576 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0530301 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0528899 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0512078 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0504806 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0503609 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.050348 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0484926 |
| COL5A2 | collagen, type V, alpha 2 | 0.0483753 |
| INSIG1 | insulin induced gene 1 | 0.0480787 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0476471 |
| SEPTIN9 | septin 9 | 0.0475057 |
| SQSTM1 | sequestosome 1 | 0.046008 |
| MMP12 | matrix metallopeptidase 12 | 0.0457763 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0451566 |
| MYADM | myeloid-associated differentiation marker | 0.0448546 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0444818 |
| EGFR | epidermal growth factor receptor | 0.0442197 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0438289 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0434559 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0434475 |
| APP | amyloid beta (A4) precursor protein | 0.0432148 |
| TPM3 | tropomyosin 3 | 0.0431402 |
| NBEAL1 | neurobeachin-like 1 | 0.0431242 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0425023 |
| RND3 | Rho family GTPase 3 | 0.0421964 |
| COL5A1 | collagen, type V, alpha 1 | 0.0417101 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0414891 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0403294 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0401402 |
| COPA | coatomer protein complex, subunit alpha | 0.0401127 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0390642 |
| USP34 | ubiquitin specific peptidase 34 | 0.0388302 |
| MYOF | myoferlin | 0.0388188 |
| FLNB | filamin B, beta | 0.038796 |
| FAM219A | family with sequence similarity 219, member A | 0.0378767 |
| HDLBP | high density lipoprotein binding protein | 0.0377529 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0377478 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0376995 |
| LOX | lysyl oxidase | 0.0374129 |
| TAOK1 | TAO kinase 1 | 0.0367231 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0363524 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0360826 |
| OGA | O-GlcNAcase | 0.0358993 |
| UBC | ubiquitin C | 0.0357593 |
| MSN | moesin | 0.0354121 |
| FBN1 | fibrillin 1 | 0.035348 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0351575 |
| GOLGB1 | golgin B1 | 0.0345543 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0345267 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0343021 |
| CALR | calreticulin | 0.034137 |
| AFF4 | AF4/FMR2 family, member 4 | 0.033808 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0333624 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0332166 |
| DSPP | dentin sialophosphoprotein | 0.0331943 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0331528 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0329166 |
| OPTN | optineurin | 0.0327357 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0325839 |
| LDHA | lactate dehydrogenase A | 0.0325473 |
| VEGFA | vascular endothelial growth factor A | 0.0322833 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0322481 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.031816 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0315285 |
| MAP1B | microtubule-associated protein 1B | 0.0305972 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0302831 |
| SPAG9 | sperm associated antigen 9 | 0.0300821 |
| NCOR2 | nuclear receptor corepressor 2 | 0.030003 |
| HDAC9 | histone deacetylase 9 | 0.0299843 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0298917 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0297944 |
| SBF2 | SET binding factor 2 | 0.0296893 |
| MAP4 | microtubule-associated protein 4 | 0.0294632 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0293202 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.210206 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16956 |
| TMSB10 | thymosin beta 10 | -0.135935 |
| S100A10 | S100 calcium binding protein A10 | -0.115316 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.102731 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0841855 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0627483 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0575805 |
| HLA-B | major histocompatibility complex, class I, B | -0.0519675 |
| CD44 | CD44 molecule (Indian blood group) | -0.0516189 |
| PLAT | plasminogen activator, tissue | -0.0508475 |
| MT1X | metallothionein 1X | -0.0434218 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0411506 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0410863 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0409402 |
| ANXA2 | annexin A2 | -0.0386952 |
| RPL35A | ribosomal protein L35a | -0.0364002 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0359119 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0358647 |
| RPL23 | ribosomal protein L23 | -0.0350999 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0349855 |
| HLA-C | major histocompatibility complex, class I, C | -0.033682 |
| RPLP2 | ribosomal protein, large, P2 | -0.0323661 |
| PRSS23 | protease, serine, 23 | -0.0313984 |
| B2M | beta-2-microglobulin | -0.0313326 |
| RPL12 | ribosomal protein L12 | -0.0299005 |
| RPL35 | ribosomal protein L35 | -0.0293322 |
| RPS24 | ribosomal protein S24 | -0.0290002 |
| RPL28 | ribosomal protein L28 | -0.028648 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0285632 |
| RIGI | RNA sensor RIG-I | -0.0283375 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.027865 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0271047 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0264268 |
| RPS8 | ribosomal protein S8 | -0.0263505 |
| RPLP1 | ribosomal protein, large, P1 | -0.0262387 |
| RPS19 | ribosomal protein S19 | -0.0261195 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0255852 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0247412 |
| FAM162A | family with sequence similarity 162, member A | -0.0245231 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.024469 |
| RPL36 | ribosomal protein L36 | -0.0240672 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.0238959 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.023351 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0231947 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0228332 |
| MX2 | MX dynamin-like GTPase 2 | -0.0228043 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0227868 |
| RRM2 | ribonucleotide reductase M2 | -0.0225599 |
| GLIS3 | GLIS family zinc finger 3 | -0.0224692 |
| S100A11 | S100 calcium binding protein A11 | -0.0224145 |
| RPL9 | ribosomal protein L9 | -0.0220379 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0215826 |
| SEPTIN7 | septin 7 | -0.0213559 |
| H3-3B | H3.3 histone B | -0.0208899 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0207574 |
| RPS21 | ribosomal protein S21 | -0.0207011 |
| RPS15 | ribosomal protein S15 | -0.02041 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0201181 |
| HMGB1 | high mobility group box 1 | -0.0198254 |
| RPL34 | ribosomal protein L34 | -0.0198164 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0195959 |
| RPS14 | ribosomal protein S14 | -0.0193896 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0193836 |
| IER3 | immediate early response 3 | -0.0191914 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0191731 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0189953 |
| DIAPH3 | diaphanous-related formin 3 | -0.0187605 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0187125 |
| THBS2 | thrombospondin 2 | -0.0184306 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0184217 |
| RPS5 | ribosomal protein S5 | -0.0182768 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0179807 |
| NPR2 | natriuretic peptide receptor 2 | -0.0176657 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.017405 |
| RPL19 | ribosomal protein L19 | -0.0172683 |
| RPL37 | ribosomal protein L37 | -0.017153 |
| RPS11 | ribosomal protein S11 | -0.0171401 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0170739 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0170502 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0170253 |
| RPL31 | ribosomal protein L31 | -0.016976 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0169449 |
| OSMR | oncostatin M receptor | -0.0169179 |
| RPS20 | ribosomal protein S20 | -0.0168863 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0167915 |
| PMP22 | peripheral myelin protein 22 | -0.0165076 |
| RPL30 | ribosomal protein L30 | -0.0164134 |
| RPS12 | ribosomal protein S12 | -0.0163663 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0162194 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0161703 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0161433 |
| RPS13 | ribosomal protein S13 | -0.0161199 |
| S100A6 | S100 calcium binding protein A6 | -0.0160877 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0160596 |
| S100A9 | S100 calcium binding protein A9 | -0.0160435 |
| H2AC6 | H2A clustered histone 6 | -0.0160241 |
| RPL27 | ribosomal protein L27 | -0.0159856 |
| RPS27 | ribosomal protein S27 | -0.0159099 |
| RPL11 | ribosomal protein L11 | -0.0156576 |
