| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.148148 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.101118 |
| ASPH | aspartate beta-hydroxylase | 0.0845956 |
| TMSB10 | thymosin beta 10 | 0.0789708 |
| USP34 | ubiquitin specific peptidase 34 | 0.0695442 |
| JMJD1C | jumonji domain containing 1C | 0.0672172 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.066144 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0637821 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0632474 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0628337 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0562749 |
| FTL | ferritin, light polypeptide | 0.0553346 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0543863 |
| YAP1 | Yes-associated protein 1 | 0.0533287 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0530719 |
| RPLP1 | ribosomal protein, large, P1 | 0.0529422 |
| ZNF638 | zinc finger protein 638 | 0.050677 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0494887 |
| NLGN1 | neuroligin 1 | 0.0493441 |
| CPOX | coproporphyrinogen oxidase | 0.0488945 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0467582 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0448775 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0448039 |
| H1-0 | H1.0 linker histone | 0.044288 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0441762 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0436342 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0433888 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0428935 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0428279 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0426204 |
| CANX | calnexin | 0.0409884 |
| PRELID2 | PRELI domain containing 2 | 0.0404228 |
| ZNF292 | zinc finger protein 292 | 0.039957 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0387859 |
| PCM1 | pericentriolar material 1 | 0.0386744 |
| EPHA6 | EPH receptor A6 | 0.0386612 |
| WWOX | WW domain containing oxidoreductase | 0.038658 |
| ENO1 | enolase 1, (alpha) | 0.038045 |
| AHNAK | AHNAK nucleoprotein | 0.0374086 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.037161 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0363715 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0359628 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0357651 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0356696 |
| YEATS2 | YEATS domain containing 2 | 0.0347709 |
| PCDH9 | protocadherin 9 | 0.034675 |
| MKI67 | marker of proliferation Ki-67 | 0.0343533 |
| RRM2 | ribonucleotide reductase M2 | 0.0340697 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.033988 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0339764 |
| HELZ | helicase with zinc finger | 0.0336456 |
| CEP192 | centrosomal protein 192kDa | 0.0332981 |
| EZR | ezrin | 0.0330782 |
| MGAT4C | MGAT4 family, member C | 0.0324904 |
| RPL35A | ribosomal protein L35a | 0.0317036 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0316532 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0315914 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0312605 |
| XPO1 | exportin 1 | 0.031068 |
| NHSL1 | NHS-like 1 | 0.0309761 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0309559 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0308065 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0307052 |
| PTMA | prothymosin, alpha | 0.0304632 |
| MED13L | mediator complex subunit 13-like | 0.0299818 |
| MORF4L2 | mortality factor 4 like 2 | 0.0299652 |
| ANK2 | ankyrin 2, neuronal | 0.0294816 |
| PHF21A | PHD finger protein 21A | 0.0292861 |
| AUTS2 | autism susceptibility candidate 2 | 0.0292641 |
| ANXA1 | annexin A1 | 0.0291114 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0290868 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0289083 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0288109 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0286792 |
| BBX | bobby sox homolog (Drosophila) | 0.0286024 |
| FAM168A | family with sequence similarity 168, member A | 0.0284118 |
| PCBP2 | poly(rC) binding protein 2 | 0.0283088 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0281969 |
| BRD2 | bromodomain containing 2 | 0.0281606 |
| RPLP2 | ribosomal protein, large, P2 | 0.0280153 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0279561 |
| IPO7 | importin 7 | 0.0278206 |
| RSF1 | remodeling and spacing factor 1 | 0.0276797 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0276219 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.027557 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.027239 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0272175 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0271917 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0271612 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0271289 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0268654 |
| VMP1 | vacuole membrane protein 1 | 0.0268022 |
| SMYD3 | SET and MYND domain containing 3 | 0.0267902 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0266656 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0264883 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0263722 |
| EHBP1 | EH domain binding protein 1 | 0.0261501 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0259132 |
| USP47 | ubiquitin specific peptidase 47 | 0.0258527 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0257984 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.138876 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0979548 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0796079 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0764681 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0729527 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0708108 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0689431 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0676325 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0631034 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0552275 |
| ZNF804A | zinc finger protein 804A | -0.0459133 |
| PCDH7 | protocadherin 7 | -0.0450421 |
| CMIP | c-Maf inducing protein | -0.0437696 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0429973 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0400064 |
| RASAL2 | RAS protein activator like 2 | -0.0393177 |
| CLDN1 | claudin 1 | -0.0380192 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0367761 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0362095 |
| RPS2 | ribosomal protein S2 | -0.0359491 |
| CDK17 | cyclin-dependent kinase 17 | -0.0351015 |
| MYPN | myopalladin | -0.0344489 |
| KLF6 | Kruppel-like factor 6 | -0.0335542 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0334938 |
| AREG | amphiregulin | -0.0331076 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0329512 |
| PLK2 | polo-like kinase 2 | -0.031262 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0307167 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0302882 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0288625 |
| TUBA1B | tubulin, alpha 1b | -0.0278565 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0275886 |
| WDR43 | WD repeat domain 43 | -0.027584 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0273135 |
| CDK6 | cyclin-dependent kinase 6 | -0.0258773 |
| RPL26 | ribosomal protein L26 | -0.0255229 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.024879 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0247852 |
| LMO7 | LIM domain 7 | -0.0239722 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0232687 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0232571 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0231272 |
| AK1 | adenylate kinase 1 | -0.022977 |
| ZFP91 | ZFP91 zinc finger protein | -0.0227997 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.022741 |
| ZNF217 | zinc finger protein 217 | -0.0213839 |
| OXR1 | oxidation resistance 1 | -0.0208605 |
| TEAD4 | TEA domain family member 4 | -0.0208557 |
| PDGFC | platelet derived growth factor C | -0.0207553 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.020505 |
| RPLP0 | ribosomal protein, large, P0 | -0.0202356 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0199197 |
| MPG | N-methylpurine-DNA glycosylase | -0.0198194 |
| RPS7 | ribosomal protein S7 | -0.0197709 |
| EDARADD | EDAR-associated death domain | -0.0197042 |
| ASTN2 | astrotactin 2 | -0.0195921 |
| TPI1 | triosephosphate isomerase 1 | -0.0195637 |
| RNF13 | ring finger protein 13 | -0.0192956 |
| NABP1 | nucleic acid binding protein 1 | -0.0190076 |
| BCHE | butyrylcholinesterase | -0.018639 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0180534 |
| LDHB | lactate dehydrogenase B | -0.0180337 |
| VCL | vinculin | -0.017922 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0178779 |
| TMEM123 | transmembrane protein 123 | -0.0176971 |
| SYT1 | synaptotagmin I | -0.0176356 |
| RAB10 | RAB10, member RAS oncogene family | -0.0175974 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0175524 |
| NUP98 | nucleoporin 98kDa | -0.0175086 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0174315 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | -0.0173954 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0169998 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.0166144 |
| GASK1B | golgi associated kinase 1B | -0.016583 |
| PDCD5 | programmed cell death 5 | -0.0164002 |
| PKP4 | plakophilin 4 | -0.01627 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0162682 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.016221 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0160548 |
| YBX1 | Y box binding protein 1 | -0.0158893 |
| EGR1 | early growth response 1 | -0.0158694 |
| GPR15 | G protein-coupled receptor 15 | -0.0157391 |
| EDN1 | endothelin 1 | -0.0157153 |
| YBX3 | Y box binding protein 3 | -0.0156917 |
| TMEM131 | transmembrane protein 131 | -0.0156553 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0156488 |
| KLF10 | Kruppel-like factor 10 | -0.01559 |
| WWC2 | WW and C2 domain containing 2 | -0.0155248 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.015417 |
| CALD1 | caldesmon 1 | -0.0153227 |
| CCND1 | cyclin D1 | -0.0151924 |
| CCNG1 | cyclin G1 | -0.0149872 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0149011 |
| MTAP | methylthioadenosine phosphorylase | -0.0148773 |
| TMEM41B | transmembrane protein 41B | -0.0148398 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0148199 |
| GTF2E2 | general transcription factor IIE, polypeptide 2, beta 34kDa | -0.014784 |
| MED14 | mediator complex subunit 14 | -0.0146697 |
| PFN1 | profilin 1 | -0.0146062 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0145969 |
