| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0853988 |
| MSN | moesin | 0.0741051 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.067927 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0566161 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0565444 |
| SMAD3 | SMAD family member 3 | 0.0558918 |
| AXL | AXL receptor tyrosine kinase | 0.0548157 |
| PCBP2 | poly(rC) binding protein 2 | 0.0482987 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0475835 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0474973 |
| WDR43 | WD repeat domain 43 | 0.0450637 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0431417 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0427101 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0421197 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0412161 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0402513 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.038654 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0352576 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0351601 |
| RNF145 | ring finger protein 145 | 0.0350575 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0345546 |
| ZFP36 | ZFP36 ring finger protein | 0.0336249 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0332065 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0331162 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.032927 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0316745 |
| CCNL1 | cyclin L1 | 0.0312851 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.031089 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0298865 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0298569 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0290245 |
| BRD2 | bromodomain containing 2 | 0.0290192 |
| RND3 | Rho family GTPase 3 | 0.0283333 |
| POTEF | POTE ankyrin domain family, member F | 0.0282202 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0281455 |
| TPM3 | tropomyosin 3 | 0.0271237 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0270993 |
| RUNX1 | runt-related transcription factor 1 | 0.0269589 |
| RPL3 | ribosomal protein L3 | 0.0267631 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0267295 |
| RASA2 | RAS p21 protein activator 2 | 0.0267133 |
| FAM107B | family with sequence similarity 107, member B | 0.0263358 |
| PCM1 | pericentriolar material 1 | 0.0259918 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0255362 |
| VMP1 | vacuole membrane protein 1 | 0.0252615 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0251233 |
| TNS1 | tensin 1 | 0.0250501 |
| ZNF638 | zinc finger protein 638 | 0.024883 |
| TGM2 | transglutaminase 2 | 0.0245205 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0244861 |
| NUP58 | nucleoporin 58 | 0.0244776 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.02443 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0241313 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0240558 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0240411 |
| MED13 | mediator complex subunit 13 | 0.0240223 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.023683 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0236167 |
| RBM25 | RNA binding motif protein 25 | 0.0235689 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0233771 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0233377 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0233049 |
| CORO1C | coronin, actin binding protein, 1C | 0.0228997 |
| FAT1 | FAT atypical cadherin 1 | 0.0220932 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0219843 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0218212 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0217825 |
| ECT2 | epithelial cell transforming 2 | 0.0216659 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0215542 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0214403 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0214338 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0213154 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0211793 |
| TOP1 | topoisomerase (DNA) I | 0.0208783 |
| COPA | coatomer protein complex, subunit alpha | 0.020725 |
| FMNL2 | formin-like 2 | 0.0206216 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.020612 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0205766 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0205626 |
| USP47 | ubiquitin specific peptidase 47 | 0.0204118 |
| CUL3 | cullin 3 | 0.0203666 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0203035 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0202903 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0202001 |
| ACTN1 | actinin, alpha 1 | 0.0200599 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0200292 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0200045 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0200035 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0199944 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0197882 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0197582 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0197267 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0196741 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0194668 |
| BRD4 | bromodomain containing 4 | 0.0194091 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0194043 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0193389 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0193009 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0192035 |
| SEPTIN9 | septin 9 | 0.0191394 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.270303 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164449 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.156441 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.144361 |
| VIM | vimentin | -0.140953 |
| ACTG1 | actin gamma 1 | -0.127684 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.1157 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0959008 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.091174 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0831978 |
| ANXA2 | annexin A2 | -0.0828232 |
| RPS24 | ribosomal protein S24 | -0.0801161 |
| NDRG1 | N-myc downstream regulated 1 | -0.0788972 |
| S100A6 | S100 calcium binding protein A6 | -0.077992 |
| KRT81 | keratin 81, type II | -0.0735604 |
| FTL | ferritin, light polypeptide | -0.0732821 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.072381 |
| RPS16 | ribosomal protein S16 | -0.069748 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0676437 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.066296 |
| MT2A | metallothionein 2A | -0.0656158 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0654915 |
| S100A10 | S100 calcium binding protein A10 | -0.0616263 |
| RPLP1 | ribosomal protein, large, P1 | -0.059761 |
| RNF213 | ring finger protein 213 | -0.0587161 |
| RPL35A | ribosomal protein L35a | -0.0586551 |
| RPL23 | ribosomal protein L23 | -0.0565505 |
| CA12 | carbonic anhydrase XII | -0.0564328 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0554315 |
| AHNAK | AHNAK nucleoprotein | -0.0548706 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0548211 |
| PTMA | prothymosin, alpha | -0.05471 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.054355 |
| RPS19 | ribosomal protein S19 | -0.0536995 |
| OSMR | oncostatin M receptor | -0.0534428 |
| AUTS2 | autism susceptibility candidate 2 | -0.0525403 |
| LDHA | lactate dehydrogenase A | -0.052477 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0519384 |
| RPS27A | ribosomal protein S27a | -0.0487647 |
| RPL12 | ribosomal protein L12 | -0.0483825 |
| RPL26 | ribosomal protein L26 | -0.0465554 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0461498 |
| RPS13 | ribosomal protein S13 | -0.0459193 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0456934 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0443564 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0441738 |
| KLF6 | Kruppel-like factor 6 | -0.0440147 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0439008 |
| ANXA4 | annexin A4 | -0.0430773 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0423315 |
| VCL | vinculin | -0.0422819 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0422475 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0418437 |
| RPLP0 | ribosomal protein, large, P0 | -0.0417673 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0416397 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.041404 |
| PGK1 | phosphoglycerate kinase 1 | -0.0412992 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0412706 |
| TMSB4X | thymosin beta 4, X-linked | -0.0411389 |
| RPS8 | ribosomal protein S8 | -0.0409142 |
| RPL19 | ribosomal protein L19 | -0.0406147 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0403408 |
| RPL38 | ribosomal protein L38 | -0.040292 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0402543 |
| EGFR | epidermal growth factor receptor | -0.0401753 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0379955 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0379013 |
| RPL7A | ribosomal protein L7a | -0.0372537 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0370171 |
| RPL31 | ribosomal protein L31 | -0.0361344 |
| RRBP1 | ribosome binding protein 1 | -0.0360099 |
| RIGI | RNA sensor RIG-I | -0.0358392 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0357338 |
| TPM4 | tropomyosin 4 | -0.0355128 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0354101 |
| RPL34 | ribosomal protein L34 | -0.035301 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0350879 |
| ATG7 | autophagy related 7 | -0.0350492 |
| SP100 | SP100 nuclear antigen | -0.0344986 |
| HLA-B | major histocompatibility complex, class I, B | -0.0335251 |
| RPL36A | ribosomal protein L36a | -0.033414 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0327084 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0326874 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0321947 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0317266 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0314581 |
| RPL37A | ribosomal protein L37a | -0.0314458 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0312123 |
| DIAPH2 | diaphanous-related formin 2 | -0.0309973 |
| IER3 | immediate early response 3 | -0.0309155 |
| RPL9 | ribosomal protein L9 | -0.0307849 |
| RPS11 | ribosomal protein S11 | -0.0307718 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0307683 |
| HLA-E | major histocompatibility complex, class I, E | -0.0307553 |
| HDLBP | high density lipoprotein binding protein | -0.0299965 |
| MT1X | metallothionein 1X | -0.029803 |
| RPS25 | ribosomal protein S25 | -0.0295494 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0295435 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0294199 |
| RPS6 | ribosomal protein S6 | -0.029197 |
