| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cloxacillin (sodium) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cloxacillin (sodium)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.105925 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.104645 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0792863 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0738022 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0736832 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.073631 |
| VEGFA | vascular endothelial growth factor A | 0.0681802 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0666055 |
| ENO1 | enolase 1, (alpha) | 0.0636367 |
| SET | SET nuclear proto-oncogene | 0.0620927 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0615818 |
| ZNF292 | zinc finger protein 292 | 0.0575189 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0571012 |
| DSPP | dentin sialophosphoprotein | 0.0561396 |
| TPD52 | tumor protein D52 | 0.0549394 |
| CEP250 | centrosomal protein 250kDa | 0.0536484 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0517312 |
| FAM13A | family with sequence similarity 13, member A | 0.0506075 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.050171 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0494502 |
| GRB10 | growth factor receptor-bound protein 10 | 0.049409 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0492204 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0490271 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0485448 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0483617 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0478439 |
| CCNY | cyclin Y | 0.0476607 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0475512 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0452576 |
| YEATS2 | YEATS domain containing 2 | 0.044814 |
| EZR | ezrin | 0.0440729 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.043601 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0419936 |
| OGA | O-GlcNAcase | 0.0416916 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0415174 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0415022 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0407682 |
| MT2A | metallothionein 2A | 0.0400461 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0398247 |
| YAP1 | Yes-associated protein 1 | 0.0397404 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0396719 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0395015 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0394382 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0392212 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0384102 |
| ANLN | anillin, actin binding protein | 0.0381597 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0378355 |
| CANX | calnexin | 0.0375339 |
| GOLGB1 | golgin B1 | 0.0371879 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0370157 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0366198 |
| PRELID2 | PRELI domain containing 2 | 0.0363936 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0354707 |
| BRD2 | bromodomain containing 2 | 0.0353761 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0353624 |
| FAM219A | family with sequence similarity 219, member A | 0.0352185 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0349899 |
| BBX | bobby sox homolog (Drosophila) | 0.0349456 |
| DTNA | dystrobrevin, alpha | 0.0341672 |
| LDHA | lactate dehydrogenase A | 0.0335933 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0334326 |
| EGFR | epidermal growth factor receptor | 0.033125 |
| RBM25 | RNA binding motif protein 25 | 0.0319911 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0314746 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0310931 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.030931 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0307851 |
| PNN | pinin, desmosome associated protein | 0.0306861 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0302938 |
| VMP1 | vacuole membrane protein 1 | 0.0301483 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0300175 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0299262 |
| FOXO3 | forkhead box O3 | 0.0298404 |
| SPAG9 | sperm associated antigen 9 | 0.0296099 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0292688 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0289536 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0289517 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0285496 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0280484 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0278471 |
| AHNAK | AHNAK nucleoprotein | 0.0278274 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0275747 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0274221 |
| HDLBP | high density lipoprotein binding protein | 0.0271588 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0270408 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0268694 |
| CENPF | centromere protein F, 350/400kDa | 0.0267976 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0263432 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0263321 |
| CEP192 | centrosomal protein 192kDa | 0.0261645 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0259766 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0257967 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0257939 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0257234 |
| FAM168A | family with sequence similarity 168, member A | 0.0255029 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.025436 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0253924 |
| TMEM165 | transmembrane protein 165 | 0.0252618 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0252378 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0252251 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CATSPERB | catsper channel auxiliary subunit beta | -0.170422 |
| RPL23 | ribosomal protein L23 | -0.127144 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.123424 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.102903 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0891113 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0831302 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.066013 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0655919 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0625408 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0617651 |
| NTN4 | netrin 4 | -0.0571355 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0563644 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.051042 |
| OSMR | oncostatin M receptor | -0.0505654 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.05052 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0488188 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0486004 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0481934 |
| KAZN | kazrin, periplakin interacting protein | -0.0455625 |
| INSR | insulin receptor | -0.045315 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0429116 |
| CDK12 | cyclin-dependent kinase 12 | -0.0403355 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0399799 |
| TMSB10 | thymosin beta 10 | -0.0367533 |
| CCND1 | cyclin D1 | -0.0364007 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.0359773 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0352132 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0330342 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0322214 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0320755 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0318395 |
| RPL12 | ribosomal protein L12 | -0.0317504 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0317044 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0303516 |
| TENM2 | teneurin transmembrane protein 2 | -0.0297459 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0294136 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0289573 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0288881 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.0286784 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0285009 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0281718 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0281199 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0280177 |
| SMIM14 | small integral membrane protein 14 | -0.0279254 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0273796 |
| SPTSSB | serine palmitoyltransferase, small subunit B | -0.027018 |
| FASN | fatty acid synthase | -0.026984 |
| ENAH | enabled homolog (Drosophila) | -0.0268844 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -0.026092 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.026087 |
| RPL34 | ribosomal protein L34 | -0.0256887 |
| CFB | complement factor B | -0.0254232 |
| KLF6 | Kruppel-like factor 6 | -0.0253116 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0253 |
| RPS24 | ribosomal protein S24 | -0.0247102 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0243913 |
| TC2N | tandem C2 domains, nuclear | -0.0243565 |
| TMC5 | transmembrane channel-like 5 | -0.0240003 |
| ANKRD30A | ankyrin repeat domain 30A | -0.0239693 |
| NRCAM | neuronal cell adhesion molecule | -0.023706 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0236787 |
| GLCCI1 | glucocorticoid induced 1 | -0.0233245 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0233039 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.022941 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0227872 |
| RPL35A | ribosomal protein L35a | -0.0227572 |
| GPC5 | glypican 5 | -0.0220409 |
| FOXP1 | forkhead box P1 | -0.0217468 |
| SEPTIN9 | septin 9 | -0.0217233 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0217022 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0215332 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0212705 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0211903 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0209288 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0208404 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0208117 |
| XBP1 | X-box binding protein 1 | -0.0207896 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0206075 |
| WWOX | WW domain containing oxidoreductase | -0.0203547 |
| GATA3 | GATA binding protein 3 | -0.0201851 |
| HLA-C | major histocompatibility complex, class I, C | -0.020136 |
| NEBL | nebulette | -0.0201114 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0200949 |
| FDPS | farnesyl diphosphate synthase | -0.0199943 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0195544 |
| NF1 | neurofibromin 1 | -0.0194022 |
| RPL35 | ribosomal protein L35 | -0.0193812 |
| FNBP1 | formin binding protein 1 | -0.0189336 |
| MACROD2 | MACRO domain containing 2 | -0.0188085 |
| KIF13B | kinesin family member 13B | -0.0185817 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0185435 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.0184637 |
| SHLD1 | shieldin complex subunit 1 | -0.018414 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0183054 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0182903 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0182406 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.0182122 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0182084 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0180671 |
| FADS2 | fatty acid desaturase 2 | -0.0180245 |
